Results 311 to 320 of about 3,326,153 (390)

Anti-stroke biologics: from recombinant proteins to stem cells and organoids. [PDF]

Stroke Vasc Neurol
Miao ZW, Wang Z, Zheng SL, Wang SN, Miao CY.   +4 more
europepmc   +1 more source

Rationale and design of ProUrokinase in Mild IsChemic strokE (PUMICE): a multicentre, prospective, randomised, open-label, blinded-endpoint controlled trial. [PDF]

Stroke Vasc Neurol
Xiong Y, Hao M, Pan Y, Duan C, Feng X, Li H, Wu N, Wang L, Meng X, Zhao X, Wang Y, PUMICE investigators*.   +11 more
europepmc   +1 more source

Anti-Inflammatory Thrombolytic JX10 (TMS-007) in Late Presentation of Acute Ischemic Stroke. [PDF]

Stroke
Niizuma K, Nishimura N, Hasegawa K, Moritoyo T, Kudo K, Bell J, Wald M, Umeda Y, Kuribayashi K, Toda Y, Tominaga T, Hasumi K.   +11 more
europepmc   +1 more source

Plasminogen as a Marker for Assessing Thrombotic Risk During Hepatitis in Cameroon: Case-Control Study. [PDF]

Health Sci Rep
Tuono RM, Tchoumke MM, Tepe WAD, Jeuta WK, Fewou SN.   +4 more
europepmc   +1 more source

Interaction of heparin with plasminogen activators and plasminogen: effects on the activation of plasminogen [PDF]

Biochemistry, 1986
The amidolytic plasmin activity of a mixture of tissue plasminogen activator (tPA) and plasminogen is enhanced by heparin at therapeutic concentrations. Heparin also increases the activity in mixtures of urokinase-type plasminogen activator (uPA) and plasminogen but has no effect on streptokinase or plasmin. Direct analyses of plasminogen activation by
Patricia Andrade-Gordon, Sidney Strickland   +1 more
openaire   +2 more sources

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Mechanisms of Plasminogen Activation by Mammalian Plasminogen Activators

Enzyme, 1988
Plasminogen activators convert the proenzyme plasminogen to the active serine protease plasmin by hydrolysis of the Arg560-Val561 peptide bond. Physiological plasminogen activation is however regulated by several additional molecular interactions resulting in fibrin-specific clot lysis.
H R Lijnen, D Collen
openaire   +2 more sources

Plasminogen/plasminogen activator and growth factor activation.

Ciba Foundation symposium, 1997
The plasminogen/plasminogen activator system is widely used in extracellular proteolysis. In this review the involvement of this system in tumour invasion, cell migration, growth factor presentation and inhibition of angiogenesis are discussed.
Rifkin, DB, Gleizes, PE, Harpel, J, Nunes, I, Munger, J, Mazzieri, R, Noguera, I   +6 more
openaire   +3 more sources

Plasminogen Activator and Plasminogen Activator Inhibitor Activities in a Reference Population

American Journal of Clinical Pathology, 1988
The influence of age, gender, and aspirin ingestion on plasma levels of tissue plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) activities was studied in a reference population of 35 men and 35 women between the ages of 20 and 65 years.
Barbara M. Alving, Douglas B. Tang, Charles F. Barr, Chitra Krishnamurti   +3 more
openaire   +3 more sources

Plasminogen activation by tissue plasminogen activator in the presence of platelets

Thrombosis Research, 1988
Platelets were found to provide a surface for activation of plasminogen by the tissue-type plasminogen activator (t-PA) at an optimum concentration and to potentiate the generation of plasmin by the amidolytic method, fibrin lysis time and fibrin plate method.
Katsumi Deguchi, Shigeru Shirakawa
openaire   +3 more sources