Results 101 to 110 of about 172,513 (208)

Assessing the effects of global warming and local social and economic conditions on the malaria transmission

Revista de Saúde Pública
OBJECTIVE: To show how a mathematical model can be used to describe and to understand the malaria transmission. METHODS: The effects on malaria transmission due to the impact of the global temperature changes and prevailing social and economic conditions
Hyun M Yang, Marcelo U Ferreira
doaj  

Challenges Associated with Scaling up Artemisinin Combination Therapy in Sub-Saharan Africa ; A Review Article

Libyan Journal of Medicine, 2008
Malaria is the leading cause of morbidity and mortality in Sub-Saharan Africa. One key strategic intervention is provision of early diagnosis and prompt effective treatment.
Qader SS, Njuguna J
doaj  

Population pharmacokinetics of lumefantrine in pregnant and non‐pregnant women with uncomplicated Plasmodium falciparum malaria in Western Kenya

British Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 911-921, March 2026.
Aim This study intends to assess the pharmacokinetic properties and treatment response of lumefantrine in pregnant and non‐pregnant women with uncomplicated Plasmodium falciparum malaria infection in Western Kenya. Methods Seventy‐five women with uncomplicated P.
Elizabeth Juma, Junjie Ding, Martin Ongas, Nelly Koskei, Kevin Onyango, Florence Oloo, Rashid Aman, Gilbert Kokwaro, Joel Tarning, Bernhards Ogutu   +9 more
wiley   +1 more source

Gonadulin and Insulin‐Like Growth Factor Involved in Rhipicephalus microplus Reproduction

Entomologia Experimentalis et Applicata, Volume 174, Issue 3, Page 285-295, March 2026.
Insulin‐like growth factor (IGF2) in ovaries of Rhipicephalus microplus partially engorged females. Ovaries from females at different feeding stages were used to detect IGF2. ABSTRACT Gonadulin and insulin‐like growth factor (IGF) are neuropeptides synthesized by the central nervous system (CNS) of arthropods.
Jéssica Waldman, Lucas Teixeira de Castro, Vinícius Andrade‐Silva, Jéssica Andrade Paes, Luís Fernando Parizi, Maria Aparecida Juliano, Saulo Petinatti Pavarini, David Driemeier, Itabajara da Silva Vaz Jr.   +8 more
wiley   +1 more source

Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe, Tamara Zoran, Marylyn Martina Addo   +2 more
wiley   +1 more source

Gaining extensive resistance against clubroot disease through the disruption of a susceptibility gene

Journal of Integrative Plant Biology, Volume 68, Issue 3, Page 559-561, March 2026.
This Commentary examines research by Wu et al. showing that β‐1,3‐glucan synthase‐like 5 (GSL5) functions as a key gene for susceptibility to clubroot in Brassica family members by suppressing immunity regulated by jasmonic acid. Inaction of GSL5 through genome editing provides broad‐spectrum resistance to clubroot.
Qibin Wu, Zhen Zeng, Daowen Wang, Zheng Qing Fu, Youxiong Que   +4 more
wiley   +1 more source

Integrating the Microbiome Into Infection Ecology and Evolution in Wild Animals

Molecular Ecology, Volume 35, Issue 5, March 2026.
ABSTRACT Parasites are a ubiquitous force in nature threatening wildlife populations and ecosystems. Interactions between hosts and their parasites are impacted by host‐associated microbiomes, which are essential for host development, physiology and immunity.
Jingdi Li, Ian Will, Luís M. Silva, Tommy J. Travers‐Cook, Paradyse E. Blackwood, Kayla C. King   +5 more
wiley   +1 more source

Genetic Surveillance Reveals Differential Evolutionary Dynamic of Anopheles gambiae Under Contrasting Insecticidal Tools Used in Malaria Control

Molecular Ecology, Volume 35, Issue 5, March 2026.
ABSTRACT Malaria, a febrile disease caused by the Plasmodium parasites and transmitted by mosquitoes, is a leading cause of mortality in children under 5 in endemic countries. The widespread deployment of insecticide‐treated bed nets (ITNs) has significantly reduced malaria transmission, but rising levels of insecticide resistance threaten to halt the ...
Harun N. Njoroge, Lilian Namuli, Sanjay C. Nagi, Anastasia Hernandez‐Koutoucheva, Daniel P. McDermott, Erin Knight, Samuel Gonahasa, Amy Lynd, Ambrose Oruni, Catherine Maiteki‐Sebuguzi, Jimmy Opigo, Adoke Yeka, Agaba Katureebe, Mary Kyohere, Moses R. Kamya, Grant Dorsey, Janet Hemingway, Sarah G. Staedke, Chris Clarkson, Alistair Miles, Eric R. Lucas, Martin J. Donnelly   +21 more
wiley   +1 more source

Erythrocyte Membrane Protein 3 (EMAP3) Is Exposed on the Surface of the Plasmodium berghei Infected Red Blood Cell

Molecular Microbiology, Volume 125, Issue 3, Page 233-249, March 2026.
Erythrocyte membrane protein 3 (EMAP3) is a novel Plasmodium berghei protein that is trafficked to the outer membrane surface of the infected red blood cell (iRBC). EMAP3 is not critical for parasite growth or sequestration but offers a new scaffold for displaying Plasmodium falciparum proteins on iRBCs.
Sophia Raine C. Hernandez, Ravish Rashpa, Thorey K. Jonsdottir, Martina S. Paoletta, Josy ter Beek, María Rayón Díaz, Jelte M. M. Krol, Severine Chevalley‐Maurel, Takahiro Ishizaki, Ronnie P.‐A. Berntsson, Chris J. Janse, Blandine Franke‐Fayard, Mathieu Brochet, Ellen S. C. Bushell   +13 more
wiley   +1 more source

Artemisinin‐Based Combination Therapies in East Africa: A Systematic Review of Quality, Clinical Efficacy, and Regulatory Progress Towards Sustainable Malaria Control

Tropical Medicine &International Health, Volume 31, Issue 3, Page 254-273, March 2026.
ABSTRACT Background Malaria is a major public health issue in East Africa, leading to widespread illness and fatalities, especially among vulnerable populations such as children under 5 years of age and pregnant women. Artemisinin‐based combination therapies (ACTs) are the primary treatment modality; however, their efficacy is undermined by the ...
Yesuneh Tefera Mekasha, Addisu Afrassa Tegegne, Tapfumanei Mashe, Million Girma, Gemmechu Hasen, Sileshi Belew   +5 more
wiley   +1 more source