The Pigment of the Malaria Parasite Plasmodium berghei [PDF]
Journal of General Microbiology, 1953 SUMMARY: The pigment of Plasmodium berghei, a recently discovered parasite of a wild rodent, Thamnomys surdaster, in the Belgian Congo, has been isolated from the infected red cells of young rats in which the strain is maintained in the laboratory. It has been shown by chemical and spectroscopical evidence to be haematin.
J. D. Fulton, C. Rimington
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Behaviour of Plasmodium berghei in some Rodents [PDF]
Nature, 1950 Plasmodium berghei Vincke and Lips 1948 is the first plasmodium found infective for rats and mice1. Vincke and Lips isolated this parasite from a wild tree-rat Thamnonys and found that it produced a fatal infection in mice and rats.
S. Adler, Meir Yoeli, A. Zuckerman
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Transcriptome analysis reveals a de novo DNA element that may interact with chromatin-associated proteins in Plasmodium berghei during erythrocytic development [PDF]
Scientific ReportsThe life cycle of Plasmodium parasites involves intricate, multistage processes that are tightly regulated by stage-specific transcription factors. These factors bind to regulatory regions within gene promoters, enabling the precise expression of genes ...
Adaobi Okafor +3 more
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CSP ubiquitylation favours Plasmodium berghei survival during early liver stage infection [PDF]
Scientific ReportsThe circumsporozoite protein (CSP), an essential protein that covers the surface of the Plasmodium sporozoite, is a key player in multiple stages of the parasite development within the mosquito and during interactions between sporozoites and mammalian ...
Sara J. S. Baptista +7 more
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Extracellular ATP triggers proteolysis and cytosolic Ca2+ rise in
Malaria Journal, 2012 Background Plasmodium has a complex cell biology and it is essential to dissect the cell-signalling pathways underlying its survival within the host. Methods Using the fluorescence resonance energy transfer (FRET) peptide substrate Abz-AIKFFARQ-EDDnp and
Cruz Laura +6 more
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Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei [PDF]
Scientific ReportsMalaria is caused by protozoan parasites of the genus Plasmodium and remains a global health concern. The parasite has a highly adaptable life cycle comprising successive rounds of asexual replication in a vertebrate host and sexual maturation in the ...
Samhita Das +10 more
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The phosphatase inhibitor BVT-948 can be used to efficiently screen functional sexual development proteins in the malaria parasite Plasmodium berghei [PDF]
International Journal for Parasitology: Drugs and Drug ResistanceBackground: Studying and discovering the molecular mechanism of Plasmodium sexual development is crucial for the development of transmission blocking drugs and malaria eradication.
Xitong Jia +9 more
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P. berghei telomerase subunit TERT is essential for parasite survival [PDF]
, 2014 Telomeres define the ends of chromosomes protecting eukaryotic cells from chromosome instability and eventual cell death. The complex regulation of telomeres involves various proteins including telomerase, which is a specialized ribonucleoprotein ...
Janse, Chris J. +4 more
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Exit of Plasmodium Sporozoites from Oocysts Is an Active Process That Involves the Circumsporozoite Protein [PDF]
, 2005 Plasmodium sporozoites develop within oocysts residing in the mosquito midgut. Mature sporozoites exit the oocysts, enter the hemolymph, and invade the salivary glands.
Fujioka, Hisashi +2 more
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Journal of Agromedicine and Medical Sciences (AMS), 2021 Malaria is a health problem for the world's population and is predominantly located in tropical and subtropical areas. The three countries with the most malaria cases are India (58%), followed by Indonesia (20%), then Myanmar (16%).
Zainabur Rahmah
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