Results 121 to 130 of about 124,584 (310)
Cellular Microbiology, 2013 Successful gametogenesis of the malaria parasite depends on egress of the gametocytes from the erythrocytes within which they developed. Egress entails rupture of both the parasitophorous vacuole membrane and the erythrocyte plasma membrane, and precedes
E. Deligianni +9 more
semanticscholar +1 more source
Different Derivatives of Plumbagin Analogue: Bioavailability and Their Toxicity Studies
Food Science &Nutrition, Volume 13, Issue 8, August 2025.Plumbagin, discovered in Plumbago zeylanica, has potential therapeutic effects such as anticancer, antimicrobial, and anti‐inflammatory characteristics. It has traditionally been used to treat anemia and rheumatic pain, but its therapeutic application is limited because of low bioavailability and toxicity risk factors.
Souparnika Thekkumkara +6 more
wiley +1 more source
The multifunctional autophagy pathway in the human malaria parasite, Plasmodium falciparum. [PDF]
, 2013 Autophagy is a catabolic pathway typically induced by nutrient starvation to recycle amino acids, but can also function in removing damaged organelles. In addition, this pathway plays a key role in eukaryotic development. To date, not much is known about
Bunnik, Evelien M +9 more
core +4 more sources
The Curative and Prophylactic Effects of Xylopic Acid on Plasmodium berghei Infection in Mice
Journal of Parasitology Research, 2013 Efforts have been intensified to search for more effective antimalarial agents because of the observed failure of some artemisinin-based combination therapy (ACT) treatments of malaria in Ghana.
J. N. Boampong +6 more
semanticscholar +1 more source
Global Change Biology, Volume 31, Issue 8, August 2025.This study shows that fluctuating warm and humid conditions impact immune defenses, accelerate development, enhance post‐infection survival, and alter gene expression in mosquitoes, with potentially significant implications for their ability to vector malaria.
Thais Lemos‐Silva +3 more
wiley +1 more source
Lead clinical and pre-clinical antimalarial drugs can significantly reduce sporozoite transmission to vertebrate populations [PDF]
, 2014 To achieve malarial elimination we must employ interventions that reduce the exposure of human populations to infectious mosquitoes. To this end, numerous anti-malarial drugs are under assessment in a variety of transmission-blocking assays which fail to
Blagborough, A.M. +9 more
core +4 more sources
Investigating the evolution of apoptosis in malaria parasites: the importance of ecology [PDF]
, 2010 Apoptosis is a precisely regulated process of cell death which occurs widely in multicellular organisms and is essential for normal development and immune defences.
Colegrave, Nick +4 more
core +2 more sources
In Vitro and In Vivo Antimalarial Activity of LZ1, a Peptide Derived from Snake Cathelicidin
Toxins, 2019 Antimalarial drug resistance is an enormous global threat. Recently, antimicrobial peptides (AMPs) are emerging as a new source of antimalarials. In this study, an AMP LZ1 derived from snake cathelicidin was identified with antimalarial activity.
Yaqun Fang +8 more
doaj +1 more source
A conserved U-rich RNA region implicated in regulation of translation in Plasmodium female gametocytes. [PDF]
, 2008 Translational repression (TR) plays an important role in post-transcriptional regulation of gene expression and embryonic development in metazoans. TR also regulates the expression of a subset of the cytoplasmic mRNA population during development of
Braks, J.A.M. +4 more
core +2 more sources
Malaria Journal, 2019 Background The immune modulating potential of IL-35 in multiple human disorders has been reported. Consequent upon the recognition of inflammatory cytokine activation and its preponderance for mediating pathology during malaria infection, the study aimed
Ramatu Omenesa Bello +8 more
doaj +1 more source