Results 91 to 100 of about 100,185 (210)
ABSTRACT Objective Malaria and anaemia are significant public health challenges among young children in Burkina Faso, with complex interactions between climate variability, food security, and nutrient deficiencies. This study aimed to identify the malariometric profile and nutrient patterns among young children and to determine the associations of ...
Adi Lukas Kurniawan +8 more
wiley +1 more source
Comparative structure-function features of Hsp70s of Plasmodium falciparum and human origins [PDF]
Graham Chakafana +2 more
openalex +1 more source
Ein neuer Malariawirkstoff hemmt die Proteinsynthese von Plasmodium falciparum
Die Verbindung 31 stellt einen vielversprechenden Ansatz für die Entwicklung eines Malariawirkstoffs mit einem starken Wirkungsprofil dar (PfNF54 IC50 ± s.d. = 3,9 ± 0,4 nM). Sie hat einen neuartigen Wirkmechanismus, indem sie an zytosolische Ribosomen‐Untereinheiten bindet und dadurch die Proteinsynthese im Parasiten hemmt.
Patricia Bravo +16 more
wiley +1 more source
A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum
Compound 31 represents a promising avenue for the development as an antimalarial agent with a potent activity profile (PfNF54 IC50 ± s.d. = 3.9 ± 0.4 nM). It has a novel mode of action by binding to cytosolic ribosomal subunits, thereby inhibiting protein synthesis in the parasite.
Patricia Bravo +16 more
wiley +1 more source
Abstract Anemia affects 32 million pregnant women globally, contributing annually to more than 115 000 maternal deaths and 591 000 perinatal deaths worldwide. Low‐ and middle‐income countries (LMICs) bear the highest burden of anemia in pregnancy, with nearly 50% of affected pregnant women. It is now 2025, which is WHO's target year for a 50% reduction
Akaninyene E. Ubom +9 more
wiley +1 more source
Modular nanosensing platforms utilize nanomaterials and functionalized interfaces to amplify trace different pathogens (like tuberculosis) antigen capture, suppress matrix interference, and enable multiplex detection. Their portability and cost‐effectiveness support rapid screening in resource‐limited settings and real‐time monitoring, advancing high ...
Mei Li +6 more
wiley +1 more source
Glutathione synthetase from Plasmodium falciparum [PDF]
Svenja Meierjohann +2 more
openalex +1 more source
Malaria vaccine awareness in Ghana is driven by education, digital access, age, religion, and region. Closing digital and regional gaps is essential to reach underserved women and support Ghana's malaria elimination goals. ABSTRACT Background In Ghana, pregnant women are disproportionately affected by malaria, yet awareness of malaria vaccination ...
Michael Sarfo +4 more
wiley +1 more source
4-(1 H )-Quinolones and 1,2,3,4-Tetrahydroacridin-9(10 H )-Ones Prevent the Transmission of Plasmodium falciparum to Anopheles freeborni [PDF]
Fabián E. Saénz +6 more
openalex +1 more source
Community and healthcare worker perspectives reveal strong acceptance of malaria control programmes in the rural settings of South Africa, though challenges persist with cross‐border movement, local protests and negative spraying experiences. Strengthening community engagement remains critical for sustaining malaria elimination efforts.
May Thulisa Thembakazi +2 more
wiley +1 more source

