Results 91 to 100 of about 287,184 (330)

Benzochalcogenodiazoles, Synthesis, and Applications in Medicinal Chemistry and Photomedicine

European Journal of Organic Chemistry, EarlyView.
Benzochalcogenodiazoles (BXD) including benzoxadiazoles, benzothiadiazoles, and benzoselenadiazoles are initially mainly designed for optoelectronic materials as electron‐deficient cores. Nevertheless, they are now extending their application to biology.
Jean‐Elie Zheng, Xavier Franck, Thibault Gallavardin   +2 more
wiley   +1 more source

Performance of Microscopy for the Diagnosis of Malaria and Human African Trypanosomiasis by Diagnostic Laboratories in the Democratic Republic of the Congo: Results of a Nation-Wide External Quality Assessment. [PDF]

PLoS ONE, 2016
The present External Quality Assessment (EQA) assessed microscopy of blood parasites among diagnostic laboratories in the Democratic Republic of the Congo. The EQA addressed 445 participants in 10/11 provinces (October 2013-April 2014). Participants were
Pierre Mukadi, Veerle Lejon, Barbara Barbé, Philippe Gillet, Christophe Nyembo, Albert Lukuka, Joris Likwela, Crispin Lumbala, Justin Mbaruku, Wim Vander Veken, Dieudonné Mumba, Pascal Lutumba, Jean-Jacques Muyembe, Jan Jacobs   +13 more
doaj   +1 more source

Protection against Plasmodium falciparum malaria by PfSPZ Vaccine.

JCI Insight, 2017
BACKGROUND: A radiation-attenuated Plasmodium falciparum (Pf) sporozoite (SPZ) malaria vaccine, PfSPZ Vaccine, protected 6 of 6 subjects (100%) against homologous Pf (same strain as in the vaccine) controlled human malaria infection (CHMI) 3 weeks after ...
J. Epstein, K. Paolino, T. Richie, M. Sedegah, Alexandra Singer, A. Ruben, S. Chakravarty, April Stafford, Richard C. Ruck, A. Eappen, Tao Li, P. Billingsley, Anita Manoj, Joana C. Silva, K. Moser, R. Nielsen, Donna M Tosh, S. Cicatelli, Harini Ganeshan, Jessica Case, Debbie Padilla, S. Davidson, L. Garver, Elizabeth Saverino, Tooba Murshedkar, A. Gunasekera, P. Twomey, S. Reyes, J. Moon, Eric R. James, Natasha Kc, Minglin Li, E. Abot, A. Belmonte, Kevin Hauns, M. Belmonte, Jun Huang, C. Vásquez, Shon A. Remich, Mary Carrington, Y. Abebe, Amy Tillman, Bradley W. Hickey, J. Regules, Eileen D. Villasante, B. Sim, Stephen L. Hoffman   +46 more
semanticscholar   +1 more source

Recent Advancements in Microfluidic Biosensors for Clinical Applications

iLABMED, EarlyView.
The combination of low‐consumption microfluidic chips and high‐sensitivity biosensors enables rapid and accurate detection of complex target analytes. This integrated system holds significant potential for applications in disease diagnosis, health monitoring, and treatment management.
Haiyan Wang, Wenjuan Wu
wiley   +1 more source

The prevalence of Plasmodium falciparum in sub Saharan Africa since 1900

Nature, 2017
Malaria transmission is influenced by climate, land use and deliberate interventions. Recent declines have been observed in malaria transmission. Here we show that the African continent has witnessed a long-term decline in the prevalence of Plasmodium ...
R. Snow, B. Sartorius, D. Kyalo, Joseph Maina, P. Amratia, Clara W. Mundia, P. Bejon, A. Noor   +7 more
semanticscholar   +1 more source

Microvascular sequestration of Plasmodium falciparum

Blood, 2011
A 2-year-old boy presented to a clinic in rural Mali with fever and malaise. Thick and thin blood films stained with Giemsa (left and right, respectively) revealed that 25.7% of circulating erythrocytes were parasitized with Plasmodium falciparum (273 450 ring-stage parasites per microliter of whole blood). The child had an axillary temperature of 36.9°
Jeannette T Beaudry, Rick M. Fairhurst
openaire   +4 more sources

Activation of human NK cells by Plasmodium-infected red blood cells.

, 2012
This chapter describes a protocol to assess activation of human NK cells following in vitro stimulation with malaria-infected red blood cells. Activation is assessed by flow cytometry, staining for cell surface expression of CD69 and accumulation of ...
Horowitz, Amir, Riley, Eleanor M
core   +1 more source

Indels, structural variation, and recombination drive genomic diversity inPlasmodium falciparum [PDF]

, 2016
The malaria parasite Plasmodium falciparum has a great capacity for evolutionary adaptation to evade host immunity and develop drug resistance. Current understanding of parasite evolution is impeded by the fact that a large fraction of the genome is ...
Campino, Susana, Drury, Eleanor, Ferdig, Michael, Gould, Kelda, Hayton, Karen, Iqbal, Zamin, Kwiatkowski, Dominic, MacInnis, Bronwyn, McVean, Gil, Mead, Daniel, Miles, Alistair, Mwangi, Jonathan, O'Brien, John, Pearson, Richard, Ranford-Cartwright, Lisa, Rayner, Julian, Ruano Rubio, Valentin, Samarakoon, Upeka, Su, Xin-zhuan, Theron, Michel, Vauterin, Paul, Wellems, Thomas   +21 more
core   +3 more sources

Development of an Enzymatic Recombinase Amplification Assay for the Rapid Detection of Plasmodium Nucleic Acids

iLABMED, EarlyView.
The detection rate of enzymatic recombinase amplification (ERA) was better than that of the rapid diagnostic test. The ERA assay was more convenient than fluorescence quantitative PCR. The ERA assay can be used as a complementary tool for malaria screening and clinical diagnosis.
Xinxin Yang, Xiaoxue Lu, Junlian Yang, Wen Xu, Qian Li, Weiwei Chen   +5 more
wiley   +1 more source

Incidence of malarial infection and response to antimalarial drugs at Districts Lower Dir and Swat of Khyber Pakhtunkhwa, Pakistan

Dialogues in Health, 2022
Malaria is the leading cause of mortality and morbidity all over the world. Several antimalarial drugs are available for the treatment of malaria. The main objective of this study was to investigate the incidence of malarial infection and the use of ...
Nasib Zaman, Faiz Ul Haq, Zafran Khan, Wajahat Uallah, Daniya Ualiyeva, Yasir Waheed, Muhammad Rizwan, Raja Tahir Mahmood, Majid Mahmood   +8 more
doaj