Results 101 to 110 of about 170,206 (238)

Therapeutic Efficacy of Sulfadoxine-Pyrimethamine and Prevalence of Resistance Markers in Tanzania Prior to Revision of Malaria Treatment Policy: Plasmodium Falciparum Dihydrofolate Reductase and Dihydropteroate Synthase Mutations in Monitoring in Vivo Resistance. [PDF]

, 2004
Prior to the 2001 malarial treatment policy change in Tanzania, we conducted trials to assess the efficacy of sulfadoxine-pyrimethamine (SP) and the usefulness of molecular markers in monitoring resistance.
Abdulla, Salim, Beck, Hans-Peter, Kataraihya, Johannes, Lemnge, Martha, Malisa, Allen, Mshinda, Hassan, Mugittu, Kefas, Mwita, Alex, Ndejembi, Modesta, Nkya, Watoky, Premji, Zulfikar   +10 more
core   +1 more source

Transfusion‐transmitted malaria in India: A national survey of epidemiology and testing practices

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Malaria still poses a public health burden in India despite ongoing elimination efforts. Blood donor screening for malaria is mandated in India, yet data on transfusion‐transmitted malaria (TTM) are lacking. We sought to evaluate testing practices for malaria, associated rates of positivity in donors and reported ...
Jeremy W. Jacobs, Nabajyoti Choudhury, Satyam Arora, Aikaj Jindal, Nidhi Bhatnagar, Abhishekh Basavarajegowda, Shamee Shastry, Tulika Chandra, David Daniel, Steven J. Drews, Evan M. Bloch   +10 more
wiley   +1 more source

Epidemiological data of falciparum malaria in Ado-Odo/Ota, Southwest Ogun State, Nigeria

Data in Brief, 2018
In this data article, Blood and corresponding saliva samples from subjects presenting with fever and parasetaemia ≥2000 were obtained from selected hospitals in Ado-Odo/Ota, Ogun State over a period of two years and analyzed using Polymerase chain ...
I.Ruth Diji-geske, I.Grace Olasehinde, Irawo Fadinad, Damola Arogundade, Precious Darby   +4 more
doaj   +1 more source

A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern [PDF]

, 2003
The var multicopy gene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variant antigens, which, through their ability to adhere to a variety of host receptors, are thought to be important virulence factors.
Sue A. Kyes, Zoe Christodoulou, Ahmed Raza, Paul Horrocks, Robert Pinches, J. Alexandra Rowe, Chris I. Newbold, Aguiar, Baruch, Beeson, Berendt, Bonnefoy, Brabin, Buffet, Bull, Chen, Chen, Church, Duffy, Fidock, Fowler, Freitas-Junior, Fried, Fried, Fried, Gardner, Gardner, Goda, Kyes, Kyes, Lambros, Lekana Douki, Marsh, Newbold, Pouvelle, Reeder, Ricke, Roberts, Robson, Rowe, Rowe, Rubio, Salanti, Scherf, Smith, Smith, Smith, Su, Taylor, Trager, Vazquez-Macias, Voss   +51 more
core   +1 more source

Plasmodium falciparum virulence determinants unveiled.

Genome biology, 2002
The human malaria parasite Plasmodium falciparum, one of the world's most devastating pathogens, has an astonishing array of sequences and genes that play key roles in pathogenesis and immune evasion. We must understand the functions of these elements if the chronicity and unpredictable virulence of Plasmodium is to be explained.
Crabb, BS, Cowman, AF
openaire   +3 more sources

Genetic association between the Pfk13 gene mutation and artemisinin resistance phenotype in Plasmodium falciparum isolates from Yunnan Province, China

Malaria Journal, 2018
Background The problem of anti-malarial drug resistance is a long-term challenge faced by malaria control in Yunnan Province. Recently, the detection rates of chloroquine-resistant molecular markers (Plasmodium falciparum chloroquine resistant ...
Ying Dong, Jian Wang, Aiming Sun, Yan Deng, Mengni Chen, Yanchun Xu, Jingpo Xue   +6 more
doaj   +1 more source

Stabilizing Plasmodium falciparum proteins for small molecule drug discovery

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Early‐stage drug discovery relies on the availability of stable protein for reliable biophysical characterization of ligand binding. However, many Plasmodium falciparum proteins are challenging to produce in heterologous systems, which limits their experimental utility.
Marius Amann, Tim Sträßer, Oliver Einsle, Stefan Günther   +3 more
wiley   +1 more source

Investigation on possible transmission of monkeys' Plasmodium to human in a populations living in the equatorial rainforest of the Democratic republic of Congo

International Journal for Parasitology: Parasites and Wildlife, 2016
Plasmodiums are protozoa that may infect various hosts. Only five species are now recognized as naturally parasitizing humans: Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale and Plasmodium knowlesi.
Dieudonné Makaba Mvumbi, Thierry Lengu Bobanga, Solange Efundu Umesumbu, Billy Shako Kunyu, Jean-Marie Ntumba Kayembe, Nani-Tuma H. Situakibanza, Georges Lelo Mvumbi, Pierrette Melin, Patrick De Mol, Marie-Pierre Hayette   +9 more
doaj   +1 more source

Toxoplasma and Plasmodium protein kinases: roles in invasion and host cell remodelling [PDF]

, 2011
Some apicomplexan parasites have evolved distinct protein kinase families to modulate host cell structure and function. Toxoplasma gondii rhoptry protein kinases and pseudokinases are involved in virulence and modulation of host cell signalling.
Abdi, Agarwal, Allen, Anamika, Behnke, Billker, Billker, Bishop, Blethrow, Bracchi-Ricard, Bradley, Brian M. Cooke, Butcher, Carruthers, Carvalho, Christian Doerig, Cooke, Cooke, Coppi, Dalpke, Daniel C. Lim, Dar, Doerig, Doerig, Doerig, Dorin, Dorin, Dorin, Droucheau, El Hajj, Fennell, Fentress, Gilbert, Green, Gueirard, Halbert, Hanks, Huse, Hutti, Ishino, Jensen, Jeroen P.J. Saeij, Kafsack, Kannan, Kato, Khaminets, Khan, Khan, Khan, Kieschnick, Kun, Kuo, Labesse, Ling, Lodoen, Lourido, Luder, Manning, Martens, Melzer, Nagamune, Nunes, Nunes, Ojo, Ong, Parsons, Peixoto, Pernas, Qiu, Reese, Reese, Reese, Reininger, Reininger, Reininger, Rosenberg, Rosowski, Saeij, Saeij, Scheibel, Schneider, Shiels, Sicard, Singh, Singh, Solyakov, Sopko, Steinfeldt, Sugi, Suss-Toby, Taylor, Taylor, Tewari, Vaid, van de Sand, Ward, Ward, Wernimont, Wernimont, Xu, Yamamoto, Yasukawa, Zeqiraj, Zeqiraj, Zhao, Zhao   +105 more
core   +2 more sources

A New Conditional Transcription Factor for Use in Toxoplasma Gondii

Biotechnology Journal, Volume 21, Issue 5, May 2026.
Graphical Abstract and Lay Summary A new conditional transcription factor (CTF) for Toxoplasma gondii reversibly regulates a reporter gene, achieving an outstanding signal‐to‐noise ratio. Gene expression is robust in the absence and nearly abolished in the presence of rapamycin, and the tool's modular design will facilitate application to varied genes ...
Mohammad Farouq Sharifpour, Shadi Khadiv, Alessandro D. Uboldi, Amalie A. Jayawickrama, Sarah Manning, Jonathan Whittall, Cynthia D. K. Bottema, John T. Ellis, Daniel K. Howe, Danny W. Wilson, Farhid Hemmatzadeh, Christopher J. Tonkin, Milton M. McAllister   +12 more
wiley   +1 more source