Results 111 to 120 of about 113,438 (254)

Anaemia of Plasmodium falciparum malaria

open access: yesBaillière's Clinical Haematology, 1992
The pathophysiology of the anaemia of falciparum malaria is both complex and multifactorial, and results in a condition which is a major cause of mortality and morbidity in patients, especially children and pregnant women, living in malarial endemic areas.
Phillips, R, Pasvol, G
openaire   +2 more sources

Age‐Related and Seasonal Variation in Malaria and Other Causes of Fever and Their Association With Clinical Outcomes in Southern Angola: A Hospital‐Based Study

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Background Acute febrile illnesses in sub‐Saharan Africa are often attributed to malaria, yet many patients test negative for malaria parasites. The aetiology of nonmalarial fevers remains understudied. Here, we examine likely causes of febrile illnesses and their association with poor clinical outcomes in Angola.
Helga E. M. Gonçalves   +3 more
wiley   +1 more source

Sequence diversity and evolutionary dynamics of the dimorphic antigen merozoite surface protein-6 and other Msp genes of Plasmodium falciparum.

open access: yes, 2009
Immune evasion by Plasmodium falciparum is favored by extensive allelic diversity of surface antigens. Some of them, most notably the vaccine-candidate merozoite surface protein (MSP)-1, exhibit a poorly understood pattern of allelic dimorphism, in which
Roy, Scott W   +9 more
core   +1 more source

Uncomplicated Malaria in Infancy and Neurodevelopment at 1 and 6 Years: Evidence From the MiPPAD Birth Cohort Study of Benin

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT In malaria‐endemic regions, repeated episodes of uncomplicated malaria during infancy are common; however, their associations with neurodevelopment remain unclear. We examined relationships between malaria frequency in infancy and neurodevelopmental outcomes in early and middle childhood, using data from the APEC birth cohort nested within the
Juthathip Khongpetch   +7 more
wiley   +1 more source

Boosting antibody responses to Plasmodium falciparum merozoite antigens in children with highly seasonal exposure to infection. [PDF]

open access: yes, 2010
Longitudinal cohort studies are important to describe the dynamics of naturally acquired antibody response profiles to defined Plasmodium falciparum malaria antigens relative to clinical malaria episodes.
M. PINDER   +7 more
core   +1 more source

Submicroscopic placental infection by non-falciparum Plasmodium spp.

open access: yesPLoS Neglected Tropical Diseases, 2018
BackgroundAmong the Plasmodium species that infect humans, adverse effects of P. falciparum and P. vivax have been extensively studied and reported with respect to poor outcomes particularly in first time mothers and in pregnant women living in areas ...
Justin Y A Doritchamou   +6 more
doaj   +1 more source

Transfusion‐transmitted malaria in India: A national survey of epidemiology and testing practices

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Malaria still poses a public health burden in India despite ongoing elimination efforts. Blood donor screening for malaria is mandated in India, yet data on transfusion‐transmitted malaria (TTM) are lacking. We sought to evaluate testing practices for malaria, associated rates of positivity in donors and reported ...
Jeremy W. Jacobs   +10 more
wiley   +1 more source

Parasite infectivity and immunity to Plasmodium falciparum gametocytes in Gambian children.

open access: yes, 2004
Immunity to the sexual stages of Plasmodium falciparum can be induced during natural infections. Characterization of this immunity may facilitate the design of a transmission-blocking vaccine (TBV).
Bousema, T.   +13 more
core   +1 more source

Plasmodium falciparum picks (on) EPCR

open access: yesBlood, 2014
AbstractOf all the outcomes of Plasmodium falciparum infection, the coma of cerebral malaria (CM) is particularly deadly. Malariologists have long wondered how some patients develop this organ-specific syndrome. Data from two recent publications support a novel mechanism of CM pathogenesis in which infected erythrocytes (IEs) express specific virulence
William C, Aird   +2 more
openaire   +3 more sources

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