Characteristics of Four New Drug-Resistant Strains of Plasmodium falciparum from South-East Asia [PDF]
, 1969 D. F. Clyde +4 more
openalex +1 more source
Malaria JournalBackground Malaria elimination in Senegal requires accurate diagnosis of all Plasmodium species. Plasmodium falciparum is the most prevalent species in Senegal, although Plasmodium malariae, Plasmodium ovale, and recently Plasmodium vivax have also been ...
Aida S. Badiane +10 more
doaj +1 more source
Extracellular ATP triggers proteolysis and cytosolic Ca²⁺ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites. [PDF]
, 2012 BACKGROUND: Plasmodium has a complex cell biology and it is essential to dissect the cell-signalling pathways underlying its survival within the host. METHODS: Using the fluorescence resonance energy transfer (FRET) peptide substrate Abz-AIKFFARQ-EDDnp ...
Blackman, Michael J +6 more
core +4 more sources
Long-term sustained malaria control leads to inbreeding and fragmentation of Plasmodium vivax populations [PDF]
arXiv, 2016 Plasmodium vivax populations are more resistant to malaria control strategies than Plasmodium falciparum, maintaining high genetic diversity and gene flow even at low transmission. To quantify the impact of declining transmission on P. vivax populations, we investigated population genetic structure over time during intensified control efforts and over ...
arxiv
Observations on an apparent chloroquine-resistant strain of Plasmodium falciparum in West Africa. [PDF]
, 1965 E. E. Lasch, T. L. N'Guyen
openalex +1 more source
Molecular Detection of Malaria in South Punjab with Higher Proportion of Mixed Infections
Iranian Journal of Parasitology, 2014 Background: Malaria is well known for its fatalities worldwide, Plasmodium vivax and the Plasmodium falciparum are the two important species of malaria reported from Pakistan and creating lots of morbidities across the country.
Saba Shahzadi +5 more
doaj
Certain amplified genomic-DNA fragments (AGFs) may be involved in cell cycle progression and chloroquine is found to induce the production of cell-cycle-associated AGFs (CAGFs) in Plasmodium falciparum [PDF]
arXiv, 2015 It is well known that cyclins are a family of proteins that control cell-cycle progression by activating cyclin-dependent kinase. Based on our experimental results, we propose here a novel hypothesis that certain amplified genomic-DNA fragments (AGFs) may also be required for the cell cycle progression of eukaryotic cells and thus can be named as cell ...
arxiv
A Bayesian approach to inferring the phylogenetic structure of communities from metagenomic data [PDF]
arXiv, 2013 Metagenomics provides a powerful new tool set for investigating evolutionary interactions with the environment. However, an absence of model-based statistical methods means that researchers are often not able to make full use of this complex information.
arxiv
Mild Depression of Platelet Count and Altered Platelet Function in Acute Plasmodium Falciparum Infection [PDF]
, 1977 E.M. Essien, M.I. Ebhota
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Generating Focussed Molecule Libraries for Drug Discovery with Recurrent Neural Networks [PDF]
arXiv, 2017 In de novo drug design, computational strategies are used to generate novel molecules with good affinity to the desired biological target. In this work, we show that recurrent neural networks can be trained as generative models for molecular structures, similar to statistical language models in natural language processing.
arxiv