Results 101 to 110 of about 302,576 (367)

Plasmodium vivax-like genome sequences shed new insights into Plasmodium vivax biology and evolution [PDF]

, 2018
Although Plasmodium vivax is responsible for the majority of malaria infections outside Africa, little is known about its evolution and pathway to humans. Its closest genetic relative, P.
Arnathau, Céline, Boundenga, Larson, Durand, Patrick, Franzon, Blaise, Gilabert, Aude, Makanga, Boris, Moukodoum, Nancy D., Ngoubangoye, Barthélémy, Okouga, Alain-Prince, Ollomo, Benjamin, Otto, Thomas D., Paupy, Christophe, Prugnolle, Franck, Renaud, François, Rougeron, Virginie, Rutledge, Gavin G.   +15 more
core   +5 more sources

Evidence of Artemisinin-Resistant Plasmodium falciparum Malaria in Eastern India.

New England Journal of Medicine, 2018
Artemisinin Resistance in India In this study, possible resistance mutations and parasite survival among Plasmodium falciparum isolates obtained from patients in West Bengal, India, were investigat...
Sabyasachi Das, B. Saha, A. K. Hati, Somenath Roy   +3 more
semanticscholar   +1 more source

Genomic Content in Avian Haemosporidian Parasites Suggests Co‐Regulation of Apicoplast and Mitochondrial Nucleoids

Integrative Zoology, EarlyView.
Apicoplast genomic content and mitochondrial genomic content were found to be strongly correlated (rho = 0.93) for infections going from low to high. Apicoplast and mitochondrial genomic content were deemed as more predictive factors of parasitemia for different infection intensities.
Gaia Porporato, Peter Pibaque, Alanis Cruz Flores, Simone Cescutti, Nayden Chakarov   +4 more
wiley   +1 more source

Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria [PDF]

, 2008
Besides existing artemisinin-based combination therapies, alternative safe, effective and affordable drug combinations against falciparum malaria are needed. Methylene blue (MB) was the first synthetic antimalarial drug ever used, and recent studies have
Coulibaly, Boubacar, Klose, Christina, Kouyaté, Bocar, Mansmann, Ulrich, Meissner, Peter E., Mockenhaupt, Frank P., Müller, Olaf, Schirmer, R. Heiner, Sié, Ali, Walter-Sack, Ingeborg, Zoungrana, Augustin   +10 more
core   +1 more source

False-negative malaria rapid diagnostic tests in Rwanda: impact of Plasmodium falciparum isolates lacking hrp2 and declining malaria transmission

Malaria Journal, 2017
Rapid diagnostic tests (RDTs) for histidine rich protein 2 (HRP2) are often used to determine whether persons with fever should be treated with anti-malarials. However, Plasmodium falciparum parasites with a deletion of the hrp2 gene yield false-negative
Christina Kozycki, Noella Umulisa, S. Rulisa, E. I. Mwikarago, J. Musabyimana, J. Habimana, C. Karema, D. Krogstad   +7 more
semanticscholar   +1 more source

Population pharmacokinetics of lumefantrine in pregnant and non‐pregnant women with uncomplicated Plasmodium falciparum malaria in Western Kenya

British Journal of Clinical Pharmacology, EarlyView.
Aim This study intends to assess the pharmacokinetic properties and treatment response of lumefantrine in pregnant and non‐pregnant women with uncomplicated Plasmodium falciparum malaria infection in Western Kenya. Methods Seventy‐five women with uncomplicated P.
Elizabeth Juma, Junjie Ding, Martin Ongas, Nelly Koskei, Kevin Onyango, Florence Oloo, Rashid Aman, Gilbert Kokwaro, Joel Tarning, Bernhards Ogutu   +9 more
wiley   +1 more source

Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

Nature, 2017
Malaria is among the most serious infectious diseases affecting humans, accounting for approximately half a million deaths each year. Plasmodium falciparum causes most life-threatening cases of malaria.
Fumiji Saito, Kouyuki Hirayasu, T. Satoh, Christian W. Wang, J. Lusingu, T. Arimori, K. Shida, N. Palacpac, Sawako Itagaki, S. Iwanaga, E. Takashima, T. Tsuboi, M. Kohyama, T. Suenaga, M. Colonna, J. Takagi, T. Lavstsen, T. Horii, H. Arase   +18 more
semanticscholar   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

KLASIFIKASI PERKEMBANGBIAKAN PLASMODIUM PENYEBAB PENYAKIT MALARIA DALAM SEL DARAH MERAH MANUSIA DENGAN MENGGUNAKAN SUPPORT VECTOR MACHINE (SVM) DI KOTA JAYAPURA-PAPUA

Ilkom Jurnal Ilmiah, 2018
Malaria adalah penyakit yang ditularkan oleh nyamuk dari manusia dan hewan lain yang disebabkan oleh protozoa parasite (sekelompok mikroorganisme bersel tunggal) dalam tipe Plasmodium.
Abd. Rachman Dayat, Nur Ain Banyal
doaj   +1 more source

A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

Nature Communications, 2018
Malaria liver stages represent an ideal therapeutic target with a bottleneck in parasite load and reduced clinical symptoms; however, current in vitro pre-erythrocytic (PE) models for Plasmodium vivax and P.
Alison Roth, S. Maher, A. Conway, R. Ubalee, Victor Chaumeau, Chiara Andolina, S. A. Kaba, A. Vantaux, M. Bakowski, R. Thomson-Luque, S. Adapa, N. Singh, Samantha J Barnes, C. Cooper, M. Rouillier, C. McNamara, S. Mikolajczak, N. Sather, B. Witkowski, B. Campo, S. Kappe, D. Lanar, F. Nosten, S. Davidson, R. Jiang, D. Kyle, J. Adams   +26 more
semanticscholar   +1 more source