Plasmodium vivax and Plasmodium falciparum are becoming resistant to drugs including antifolates, sulphonamides and chloroquine. This study was focused at sequence analysis of resistant genes of these parasites against sulphadoxine–pyrimethamine and ...
Lubna Khatoon+3 more
doaj
Malaria has been a leading cause of death in human populations for centuries and remains a major public health challenge in African countries, especially affecting children. Among the five Plasmodium species infecting humans, Plasmodium falciparum is the
Alejandro Llanos-Lizcano+10 more
doaj +1 more source
A Geostatistical Framework for Combining Spatially Referenced Disease Prevalence Data from Multiple Diagnostics [PDF]
Multiple diagnostic tests are often used due to limited resources or because they provide complementary information on the epidemiology of a disease under investigation. Existing statistical methods to combine prevalence data from multiple diagnostics ignore the potential over-dispersion induced by the spatial correlations in the data.
arxiv
Characterization of antibodies to sporozoites in Plasmodium falciparum malaria and correlation with protection [PDF]
H. Kyle Webster+4 more
openalex +1 more source
The Identification and Analysis of Indicators for Predicting Malarial Incidence in Zimbabwe [PDF]
With over 50% of the country's population at risk of contracting malaria despite the introduction of several measures to combat the disease, Zimbabwe is one of the eight countries in the Malaria Elimination 8 platform of the Southern African Development Community.
arxiv
Interactions of CD4+ and CD8+ human T lymphocytes from malaria-unprimed donors with Plasmodium falciparum schizont stage [PDF]
Christian Roussilhon+4 more
openalex +1 more source
Antimalarials increase vesicle pH in Plasmodium falciparum. [PDF]
Donald J. Krogstad+2 more
openalex +1 more source
Short report: molecular markers associated with Plasmodium falciparum resistance to sulfadoxine-pyrimethamine in the Democratic Republic of Congo. [PDF]
Sulfadoxine-pyrimethamine (SP) is the first line antimalarial treatment in the Democratic Republic of Congo. Using polymerase chain reaction, we assessed the prevalence of mutations in the dihydrofolate reductase (dhfr) (codons 108, 51, 59) and ...
Bonnet, M+5 more
core +2 more sources
Recognition of a Mr 56K glycoprotein on the surface of Plasmodium falciparum merozoites by mouse monoclonal antibodies. [PDF]
Harold A. Stanley+2 more
openalex +1 more source