Results 111 to 120 of about 192,449 (275)

Genetic association between the Pfk13 gene mutation and artemisinin resistance phenotype in Plasmodium falciparum isolates from Yunnan Province, China

open access: yesMalaria Journal, 2018
Background The problem of anti-malarial drug resistance is a long-term challenge faced by malaria control in Yunnan Province. Recently, the detection rates of chloroquine-resistant molecular markers (Plasmodium falciparum chloroquine resistant ...
Ying Dong   +6 more
doaj   +1 more source

In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up. [PDF]

open access: yes, 2004
To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with follow-up of 28 days or longer that were conducted between 1990 and 2003
Adjuik, M   +16 more
core   +3 more sources

Imaging malaria parasites across scales and time

open access: yesJournal of Microscopy, EarlyView.
Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley   +1 more source

RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts. [PDF]

open access: yes, 2011
Over 50% of genes in Plasmodium falciparum, the deadliest human malaria parasite, contain predicted introns, yet experimental characterization of splicing in this organism remains incomplete.
DeRisi, Joseph L   +2 more
core   +3 more sources

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

open access: yesJournal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz   +4 more
wiley   +1 more source

Identification of Plasmodium falciparum var1CSA and var2CSA domains that bind IgM natural antibodies [PDF]

open access: yes, 2006
Malaria in pregnancy is responsible for maternal anaemia, low-birth-weight babies and infant deaths. Plasmodium falciparum infected erythrocytes are thought to cause placental pathology by adhering to host receptors such as chondroitin sulphate A (CSA ...
Ahmed Raza   +37 more
core   +1 more source

Optimisation of freeze substitution protocols for the examination of malaria parasite structure by volumetric electron microscopy

open access: yesJournal of Microscopy, EarlyView.
Abstract Malaria is one of the deadliest infectious diseases in the world, annually responsible for over 400,000 deaths. It is caused by parasites of the genus Plasmodium, which undergo remarkable structural changes during their development within different cells across various hosts.
Rachel Rachid   +3 more
wiley   +1 more source

Comparative attraction of Anopheles quadriannulatus and Anopheles arabiensis to humans estimated by comparing their relative abundance in samples of mosquito larvae and adults collected across an ecologically heterogeneous landscape in southern Tanzania Utafiti wa kulinganisha mvuto wa mbu aina ya Anopheles arabiensis na Anopheles quadriannulatus kwa binadamu katika mandhari yenye mazingira mbalimbali kusini mwa Tanzania

open access: yesMedical and Veterinary Entomology, EarlyView.
Light and barrier traps near human activity selectively captured more Anopheles arabiensis, indicating a strong attraction to humans and explicit bias in adult sampling methods. Traps placed in open glades away from humans captured species proportions similar to larval samples, suggesting reduced sampling bias in those settings. Visits by entomological
Deogratius R. Kavishe   +8 more
wiley   +1 more source

Assessing the burden of submicroscopic Plasmodium infections in a pre-elimination malaria setting in sub-Saharan Africa, Guinea-Bissau

open access: yesMalaria Journal
Background Submicroscopic Plasmodium infections can be a source of persistent malaria transmission. The aim of this study was to assess their frequency, distribution, morbidity and associated factors in a pre-elimination malaria setting in sub-Saharan ...
Ronise Silva   +4 more
doaj   +1 more source

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