Results 121 to 130 of about 296,027 (331)

Rapid diagnostic tests for molecular surveillance of Plasmodium falciparum malaria -assessment of DNA extraction methods and field applicability [PDF]

, 2013
Background: The need for new malaria surveillance tools and strategies is critical, given improved global malaria control and regional elimination efforts.
Abdullah S Ali, Anders Björkman, Andreas Mårtensson, Berit Aydin-Schmidt, Delér Shakely, DS Ishengoma, E Kamau, G Froberg, G Holmgren, G Snounou, J Hwang, José P Gil, L Cnops, LC Okell, Louise Jörnhagen, Max Petzold, MI Veiga, Mwinyi I Msellem, N Steenkeste, Pedro E Ferreira, RN Price, S Bereczky, S Dahlstrom, SA Greenspoon, SE Shokoples, Ulrika Morris, V Veron   +26 more
core   +2 more sources

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Nature, 2015
Artemisinins are the cornerstone of anti-malarial drugs. Emergence and spread of resistance to them raises risk of wiping out recent gains achieved in reducing worldwide malaria burden and threatens future malaria control and elimination on a global ...
A. Mbengue, S. Bhattacharjee, T. Pandharkar, Haining Liu, G. Estiu, R. Stahelin, Shahir S. Rizk, D. L. Njimoh, Yana Ryan, K. Chotivanich, C. Nguon, M. Ghorbal, Jose-Juan Lopez-Rubio, M. Pfrender, S. Emrich, N. Mohandas, A. Dondorp, O. Wiest, K. Haldar   +18 more
semanticscholar   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

DNA-encoded nucleosome occupancy is associated with transcription levels in the human malaria parasite Plasmodium falciparum. [PDF]

, 2014
BackgroundIn eukaryotic organisms, packaging of DNA into nucleosomes controls gene expression by regulating access of the promoter to transcription factors.
Bunnik, Evelien M, Gill, Sarjeet S, Le Roch, Karine G, Lonardi, Stefano, Polishko, Anton, Ponts, Nadia, Prudhomme, Jacques   +6 more
core   +3 more sources

Peroxisome Proliferator-Activator Receptor γ: A Link between Macrophage CD36 and Inflammation in Malaria Infection

PPAR Research, 2012
Severe malaria infection caused by Plasmodium falciparum is a global life-threatening disease and a leading cause of death worldwide. Intensive investigations have demonstrated that macrophages play crucial roles in control of inflammatory and immune ...
Yi Ren
doaj   +1 more source

[Plasmodium falciparum].

Ugeskrift for læger, 2022
Jacob Bodilsen, U. Hjort
semanticscholar   +1 more source

pfk13-Independent Treatment Failure in Four Imported Cases of Plasmodium falciparum Malaria Treated with Artemether-Lumefantrine in the United Kingdom

Antimicrobial Agents and Chemotherapy, 2017
We present case histories of four patients treated with artemether-lumefantrine for falciparum malaria in UK hospitals in 2015 to 2016. Each subsequently presented with recurrent symptoms and Plasmodium falciparum parasitemia within 6 weeks of treatment ...
C. Sutherland, Paul Lansdell, M. Sanders, Julian K Muwanguzi, Donelly A. van Schalkwyk, H. Kaur, D. Nolder, Julie Tucker, H. Bennett, T. Otto, M. Berriman, T. Patel, R. Lynn, E. Gkrania-Klotsas, P. Chiodini   +14 more
semanticscholar   +1 more source

Nanoparticle‐Based Tetracycline Delivery Systems: Advancing Therapeutic Effectiveness and Tackling Antibiotic Resistance

Particle &Particle Systems Characterization, EarlyView.
This review explores improved tetracycline (TCN) delivery via polymer‐based nanocarriers to enhance solubility, stability, and targeted release. It also covers stimuli‐responsive systems, triggered by pH, enzymes, or reactive oxygen species (ROS), and co‐delivery approaches that increase therapeutic efficacy in cancer and inflammatory diseases ...
Mahsa Molaei Nasr, Mehrab Pourmadadi, Fatemeh Yazdian, Hamid Rashedi, Abbas Rahdar, M. Ali Aboudzadeh   +5 more
wiley   +1 more source

Sri Lanka Malaria Maps [PDF]

, 2003
BACKGROUND: Despite a relatively good national case reporting system in Sri Lanka, detailed maps of malaria distribution have not been publicly available.
Amerasinghe, Felix P, Briët, Olivier JT, Gunawardena, Dissanayake M, van der Hoek, Wim   +3 more
core   +3 more sources

Identification of conserved cross-species B-cell linear epitopes in human malaria: a subtractive proteomics and immuno-informatics approach targeting merozoite stage proteins

Frontiers in Immunology
Human malaria, caused by five Plasmodium species (P. falciparum, P. vivax, P. malariae, P. ovale, and P. knowlesi), remains a significant global health burden. While most interventions target P.
Sebastian D. Musundi, Jesse Gitaka, Bernard N. Kanoi   +2 more
doaj   +1 more source