Results 131 to 140 of about 185,323 (267)

Intra-individual variability in ancient plasmodium DNA recovery highlights need for enhanced sampling

open access: yesScientific Reports
Malaria has been a leading cause of death in human populations for centuries and remains a major public health challenge in African countries, especially affecting children. Among the five Plasmodium species infecting humans, Plasmodium falciparum is the
Alejandro Llanos-Lizcano   +10 more
doaj   +1 more source

Generating Focussed Molecule Libraries for Drug Discovery with Recurrent Neural Networks [PDF]

open access: yesarXiv, 2017
In de novo drug design, computational strategies are used to generate novel molecules with good affinity to the desired biological target. In this work, we show that recurrent neural networks can be trained as generative models for molecular structures, similar to statistical language models in natural language processing.
arxiv  

Sequence analysis of genes associated with resistance to chloroquine and sulphadoxine pyrimethamine in P. falciparum and P. vivax isolates from the Bannu district of Pakistan

open access: yesBrazilian Journal of Infectious Diseases, 2013
Plasmodium vivax and Plasmodium falciparum are becoming resistant to drugs including antifolates, sulphonamides and chloroquine. This study was focused at sequence analysis of resistant genes of these parasites against sulphadoxine–pyrimethamine and ...
Lubna Khatoon   +3 more
doaj  

A Geostatistical Framework for Combining Spatially Referenced Disease Prevalence Data from Multiple Diagnostics [PDF]

open access: yesarXiv, 2018
Multiple diagnostic tests are often used due to limited resources or because they provide complementary information on the epidemiology of a disease under investigation. Existing statistical methods to combine prevalence data from multiple diagnostics ignore the potential over-dispersion induced by the spatial correlations in the data.
arxiv  

The Identification and Analysis of Indicators for Predicting Malarial Incidence in Zimbabwe [PDF]

open access: yesarXiv, 2019
With over 50% of the country's population at risk of contracting malaria despite the introduction of several measures to combat the disease, Zimbabwe is one of the eight countries in the Malaria Elimination 8 platform of the Southern African Development Community.
arxiv  

Subarachnoid haemorrhage in Plasmodium falciparum malaria [PDF]

open access: bronze, 1989
K Murugavel   +3 more
openalex   +1 more source

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