Results 131 to 140 of about 192,449 (275)

Large‐Scale Chemoenzymatic Synthesis of a Glycophorin A Tetrasaccharide Motif and Its Analogues

Asian Journal of Organic Chemistry, Volume 14, Issue 8, August 2025.
A large‐scale chemoenzymatic method was developed to synthesize natural and modified analogues of the Glycophorin A tetrasaccharide with either C9 or C5 terminal α‐2,3‐sialic acid variants. Selective α‐2,6‐sialylation of galactosamine was achieved by maintaining acetylation of the galactose during the course of enzymatic reactions. The products can aid
Ivan A. Gagarinov, Kam Lau, Robin J. Thomson, Thomas Haselhorst, Ross L. Coppel, Mark von Itzstein   +5 more
wiley   +1 more source

Improved synchronous production of Plasmodium falciparum gametocytes in vitro.

, 2007
The sexual stages of the Plasmodium falciparum life cycle are attractive targets for vaccines and transmission blocking drugs. Difficulties in culturing and obtaining large amounts of sexual stage P.
Baker, David A, Fivelman, Quinton L, McRobert, Louisa, Saeed, Maha, Sharp, Sarah, Sutherland, Colin J, Swales, Claire A, Taylor, Cathy J   +7 more
core   +1 more source

The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs

Advanced NanoBiomed Research, Volume 5, Issue 8, August 2025.
Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He, George Junior, Rajashree Konar, Yuanding Huang, Ke Zhang, Lijing Ke, Meng Niu, Boon Tong Goh, Amine El Moutaouakil, Gilbert Daniel Nessim, Mohamed Belmoubarik, Weng Kung Peng   +11 more
wiley   +1 more source

Exploration of Fluorinated Peptoid‐Based Histone Deacetylase Inhibitors as Dual‐Stage Antiplasmodial Agents

Archiv der Pharmazie, Volume 358, Issue 8, August 2025.
The antiplasmodial properties of a series of fluorinated peptoid‐based histone deacetylase (HDAC) inhibitors were evaluated by screening them for their activity against asexual blood and liver stage malaria parasites and assessing their mammalian cell toxicity, to elucidate structure–activity and structure‐toxicity relationships. Compound 1h emerged as
Nina Reßing, Daniel Stopper, Thomas Martin Schäfer, Lais Pessanha de Carvalho, Elizabeth A. Winzeler, Jana Held, Finn K. Hansen   +6 more
wiley   +1 more source

Probabilistic single‐particle cryo‐EM ab initio 3D reconstruction in SIMPLE

Acta Crystallographica Section D, Volume 81, Issue 8, Page 396-409, August 2025.
We introduce a new approach to probabilistic multi‐volume single‐particle cryo‐EM ab initio 3D reconstruction for simultaneous estimation of the relative particle 3D orientations and partitioning of the particles into groups with distinct structural states.Three‐dimensional (3D) structure determination by single‐particle analysis of cryo‐electron ...
Cong T. S. Van, Cyril F. Reboul, Joseph J. E. Caesar, Rubén Meana-Pañeda, George T. Lountos, Justin C. Deme, Owain J. Bryant, Steven Johnson, Claire T. Piczak, Eugene Valkov, Susan M. Lea, Hans Elmlund   +11 more
wiley   +1 more source

Mild Depression of Platelet Count and Altered Platelet Function in Acute Plasmodium Falciparum Infection [PDF]

, 1977
E.M. Essien, M.I. Ebhota
openalex   +1 more source

A Short‐Read Amplicon Sequencing Protocol and Bioinformatic Pipeline for Ecological Surveillance of Dipteran Disease Vectors

Molecular Ecology Resources, Volume 25, Issue 6, August 2025.
ABSTRACT Vector control remains an important strategy worldwide to prevent human infection with pathogens transmitted by arthropods. Vector control strategies rely on accurate identification of vector taxa along with vector‐specific biological indicators such as feeding ecology, infection prevalence and insecticide resistance.
Raquel Lima‐Cordón, Jason Travis Mohabir, Mohini Sooklall, Aina Martinez Zurita, Meg Shieh, Cheyenne Knox, Sabrina Gobran, Zachary Johnson, Margaret Laws, Ruchit Panchal, Reza Niles‐Robin, Horace Cox, Maria Eugenia Grillet, Jorge E. Moreno, Socrates Herrera, Martha Quinones, Angela M. Early, Jacob A. Tennessen, Daniel E. Neafsey   +18 more
wiley   +1 more source

Intra-individual variability in ancient plasmodium DNA recovery highlights need for enhanced sampling

Scientific Reports
Malaria has been a leading cause of death in human populations for centuries and remains a major public health challenge in African countries, especially affecting children. Among the five Plasmodium species infecting humans, Plasmodium falciparum is the
Alejandro Llanos-Lizcano, Michelle Hämmerle, Alessandra Sperduti, Susanna Sawyer, Brina Zagorc, Kadir Toykan Özdoğan, Meriam Guellil, Olivia Cheronet, Martin Kuhlwilm, Ron Pinhasi, Pere Gelabert   +10 more
doaj   +1 more source

Protective antibodies to plasmodium falciparum and immunity to malaria in an endemic area of Brazil [PDF]

, 1986
Carlos Eduardo Tosta, Rômulo C. Sabóia Moura   +1 more
openalex   +1 more source

Fluctuating Warm and Humid Conditions Differentially Impact Immunity and Development in the Malaria Vector Anopheles stephensi

Global Change Biology, Volume 31, Issue 8, August 2025.
This study shows that fluctuating warm and humid conditions impact immune defenses, accelerate development, enhance post‐infection survival, and alter gene expression in mosquitoes, with potentially significant implications for their ability to vector malaria.
Thais Lemos‐Silva, Emma De Neef, Yarno Valgaerts, Maria L. Simões   +3 more
wiley   +1 more source