Mild Depression of Platelet Count and Altered Platelet Function in Acute Plasmodium Falciparum Infection [PDF]
E.M. Essien, M.I. Ebhota
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Malaria has been a leading cause of death in human populations for centuries and remains a major public health challenge in African countries, especially affecting children. Among the five Plasmodium species infecting humans, Plasmodium falciparum is the
Alejandro Llanos-Lizcano+10 more
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Protective antibodies to plasmodium falciparum and immunity to malaria in an endemic area of Brazil [PDF]
Carlos Eduardo Tosta+1 more
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Generating Focussed Molecule Libraries for Drug Discovery with Recurrent Neural Networks [PDF]
In de novo drug design, computational strategies are used to generate novel molecules with good affinity to the desired biological target. In this work, we show that recurrent neural networks can be trained as generative models for molecular structures, similar to statistical language models in natural language processing.
arxiv
Surface alterations of erythrocytes in Plasmodium falciparum malaria. Antigenic variation, antigenic diversity, and the role of the spleen. [PDF]
M. Hommel, P. David, L D Oligino
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Plasmodium vivax and Plasmodium falciparum are becoming resistant to drugs including antifolates, sulphonamides and chloroquine. This study was focused at sequence analysis of resistant genes of these parasites against sulphadoxine–pyrimethamine and ...
Lubna Khatoon+3 more
doaj
A Geostatistical Framework for Combining Spatially Referenced Disease Prevalence Data from Multiple Diagnostics [PDF]
Multiple diagnostic tests are often used due to limited resources or because they provide complementary information on the epidemiology of a disease under investigation. Existing statistical methods to combine prevalence data from multiple diagnostics ignore the potential over-dispersion induced by the spatial correlations in the data.
arxiv
Characterisation of cDNA clones for hypoxanthine–guanine phosphoribosyltransferase from the human malarial parasite,Plasmodium falciparum: comparisons to the mammalian gene and protein [PDF]
Angus King, David W. Melton
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The Identification and Analysis of Indicators for Predicting Malarial Incidence in Zimbabwe [PDF]
With over 50% of the country's population at risk of contracting malaria despite the introduction of several measures to combat the disease, Zimbabwe is one of the eight countries in the Malaria Elimination 8 platform of the Southern African Development Community.
arxiv
Subarachnoid haemorrhage in Plasmodium falciparum malaria [PDF]
K Murugavel+3 more
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