Results 71 to 80 of about 302,576 (367)

Polymorphic antigens in Plasmodium falciparum [PDF]

Blood, 1989
5 years, a large number of these antigens have been cloned so that they may be investigated for their potential as components of a malaria vaccine. As a result of the sequencing studies on these cloned genes or gene fragments, a large amount of information has been obtained concerning the primary structural characteristics of Plasmodium fa/ciparum’ For
R F, Anders, J A, Smythe
openaire   +3 more sources

Persistent transmission of Plasmodium malariae and Plasmodium ovale species in an area of declining Plasmodium falciparum transmission in eastern Tanzania

PLoS Neglected Tropical Diseases, 2019
A reduction in the global burden of malaria over the past two decades has encouraged efforts for regional malaria elimination. Despite the need to target all Plasmodium species, current focus is mainly directed towards Plasmodium falciparum, and to a ...
Victor Yman, Grace M Wandell, Doreen D Mutemi, Aurelie Miglar, M. Asghar, U. Hammar, Mattias Karlsson, Ingrid Lind, Cleis Nordfjell, I. Rooth, B. Ngasala, M. V. Homann, A. Färnert   +12 more
semanticscholar   +1 more source

Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it

Immunological Reviews, 2019
Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites have the unique capacity to infect and replicate within host erythrocytes.
Anja T. R. Jensen, Yvonne Adams, L. Hviid   +2 more
semanticscholar   +1 more source

Thrombocytopenia and its Comparison with Plasmodium Vivax and Plasmodium Falciparum in Malaria Patients

Pakistan Journal of Medical Research, 2023
Background: Malaria in Pakistan is a serious public health problem and thrombocytopenia can serve as diagnostic predictive marker. Objective: The objective of present study was to find out the frequency of plasmodium vivax and falciparum in malaria ...
Maliha Ajmal, Muhammad Hassaan, Nauman Ismat Butt, Sabeen Aftab, Fahmina Ashfaq, Arsalan Iqbal Bhatti   +5 more
doaj  

The usefulness of rapid diagnostic tests in the new context of low malaria transmission in zanzibar. [PDF]

, 2013
BACKGROUND\ud \ud We assessed if histidine-rich-protein-2 (HRP2) based rapid diagnostic test (RDT) remains an efficient tool for Plasmodium falciparum case detection among fever patients in Zanzibar and if primary health care workers continue to adhere ...
A Bhattarai, A Manjurano, A Martensson, Abdullah S. Ali, Anders Björkman, Andreas Mårtensson, Berit Aydin-Schmidt, Bryan Greenhouse, Delér Shakely, E Nicastri, G Holmgren, H Reyburn, J Baker, J Baker, J Chinkhumba, K Baltzell, KB Beshir, Kimberly A. Baltzell, Kristina Elfving, LC Okell, Lorenz von Seidlein, Max Petzold, MI Msellem, MI Veiga, ML McMorrow, ML McMorrow, MS Hsiang, Mwinyi I. Msellem, OA Koita, P Gillet, P Gillet, Rahila Omar, S Dahlstrom, S Thiam, SE Shokoples, TA Abeku, Ulrika Morris, Xu Weiping, Z Bisoffi   +38 more
core   +4 more sources

Using the Plasmodium mitochondrial genome for classifying mixed-species infections and inferring the geographical origin of P. falciparum parasites imported to the U.S.

PLoS ONE, 2019
The ability to identify mixed-species infections and track the origin of Plasmodium parasites can further enhance the development of treatment and prevention recommendations as well as outbreak investigations.
Sarah E Schmedes, Dhruviben Patel, Julia Kelley, Venkatachalam Udhayakumar, Eldin Talundzic   +4 more
doaj   +1 more source

Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development [PDF]

, 2011
<p>Background: Plasmodium falciparum contains three genes encoding potential glutamate dehydrogenases. The protein encoded by gdha has previously been biochemically and structurally characterized.
Aparicio, I., Engel, P.C., Llinas, M., Muller, S., Olszewski, K., Patzewitz, E.-M., Perner, J., Storm, J.   +7 more
core   +4 more sources

Plasmodium Vivax Infection Impersonating Plasmodium Falciparum Malaria

The Eurasian Journal of Medicine, 2014
A 73-year-old woman came to the casualty ward with symptoms of syncopal attacks, weakness, fever with chills and rigors. A provisional diagnosis of Plasmodium vivax malaria was made after the blood investigations. She had deranged renal function tests, altered sensorium and low platelet count. Repeated tests for P. falciparum (Card test) were negative.
Sweta, Kakaraparthi, Raghunath, Prabhu
openaire   +2 more sources

Artemisinin resistance in Plasmodium falciparum [PDF]

The Lancet Infectious Diseases, 2014
Benoit Witkowski and colleagues reported a simple and rapid in vitro method to detect artemisinin resistance of P falciparum. They show that the slow clearance of parasites by artemisinin combination therapies is a result of a drop in susceptibility among young ring form parasites whereas susceptibility is maintained in mature stages.
Lun, Zhao-Rong, Ferreira, Pedro E, Fu, Lin-Chun   +2 more
openaire   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source