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Anaemia of Plasmodium falciparum malaria
The pathophysiology of the anaemia of falciparum malaria is both complex and multifactorial, and results in a condition which is a major cause of mortality and morbidity in patients, especially children and pregnant women, living in malarial endemic areas.
Phillips, R, Pasvol, G
openaire +3 more sources
Antibody and B cell responses to Plasmodium sporozoites [PDF]
Antibodies are capable of blocking infection of the liver by Plasmodium sporozoites. Accordingly the induction of anti-sporozoite antibodies is a major aim of various vaccine approaches to malaria.
Cockburn, Ian A.+2 more
core +2 more sources
Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway. [PDF]
A promising new compound class for treating human malaria is the imidazolopiperazines (IZP) class. IZP compounds KAF156 (Ganaplacide) and GNF179 are effective against Plasmodium symptomatic asexual blood-stage infections, and are able to prevent ...
Cheung, Andrea L+25 more
core +4 more sources
The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs
Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He+11 more
wiley +1 more source
Significance Sickle cell trait has repeatedly been identified as a major human malaria resistance factor. Despite this, the exact mechanism of resistance is unclear.
N. Archer+5 more
semanticscholar +1 more source
Adaptation of translational machinery in malaria parasites to accommodate translation of poly-adenosine stretches throughout its life cycle [PDF]
Malaria is caused by unicellular apicomplexan parasites of the ...
Djuranovic, Sergej+2 more
core +1 more source
Analysis of slow (theta) oscillations as a potential temporal reference frame for information coding in sensory cortices [PDF]
While sensory neurons carry behaviorally relevant information in responses that often extend over hundreds of milliseconds, the key units of neural information likely consist of much shorter and temporally precise spike patterns.
Christoph Kayser+3 more
core +3 more sources
A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.
BACKGROUND Recent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P.
D. Ménard+88 more
semanticscholar +1 more source
THE CULTIVATION OF THE PLASMODIUM FALCIPARUM IN VITRO [PDF]
In 1911, C. C. Bass 1 of New Orleans reported the successful cultivation of the plasmodium of malaria in vitro . He stated that he had been able to accomplish this by maintaining anaerobic conditions and a temperature of 40 C. (104 F.). Following these suggestions, Sinton 2 of London as reported in August, 1912, attempted the growth of the organisms ...
openaire +3 more sources
Background: Malaria in Pakistan is a serious public health problem and thrombocytopenia can serve as diagnostic predictive marker. Objective: The objective of present study was to find out the frequency of plasmodium vivax and falciparum in malaria ...
Maliha Ajmal+5 more
doaj