Results 91 to 100 of about 36,588 (218)
FEBS Letters, Volume 600, Issue 2, Page 251-266, January 2026.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Plasmodium falciparum full life cycle and Plasmodium ovale liver stages in humanized mice [PDF]
, 2015 Valérie Soulard +15 more
openalex +1 more source
Cover Feature: Antimalarial Agents Derived from Metal‐Amodiaquine Complexes with Activity in Multiple Stages of the Plasmodium Life Cycle (Chem. Eur. J. 55/2023) [PDF]
, 2023 Legna Colina–Vegas +10 more
openalex +1 more source
Advanced Science, Volume 13, Issue 4, 19 January 2026.This article presents a detailed ultrastructural cell atlas of Plasmodium ookinete development using advanced volume electron microscopy (v) techniques. It defines seven distinct developmental stages, revealing complex organelle interactions and offering new insights into parasite differentiation.
Nedal Darif +12 more
wiley +1 more source
Advanced Science, Volume 13, Issue 2, 9 January 2026.The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen +5 more
wiley +1 more source
Nature CommunicationsApical membrane antigen-1 (AMA1) is a conserved malarial vaccine candidate essential for the formation of tight junctions with the rhoptry neck protein (RON) complex, enabling Plasmodium parasites to invade human erythrocytes, hepatocytes, and mosquito ...
Dimuthu Angage +16 more
doaj +1 more source
Ecologies of Risk: Malaria and Settler Landscape Transformation in 19th‐Century Ontario
American Journal of Human Biology, Volume 38, Issue 1, January 2026.ABSTRACT Objectives This study examines how settler‐driven environmental change shaped malaria transmission and mortality in 19th‐century southern Ontario. It aimed to understand the biosocial and ecological conditions that sustained endemic malaria in a temperate, colonial context.
Amanda Cooke, Megan B. Brickley
wiley +1 more source
Where, When, and How? Integrating Spatiotemporal Cues in Cell Division
BioEssays, Volume 48, Issue 1, January 2026.Accurate chromosome segregation during mitosis depends on the spatial and temporal regulation of spindle assembly, kinetochore‐microtubule attachment, and checkpoint signaling. Here, we highlight how mitotic chromosomes can serve as dynamic hubs that integrate molecular cues to coordinate spindle organization and timing, ensuring faithful genome ...
Luca Cirillo +3 more
wiley +1 more source
Scent Goes Digital: The Role of Insect Odorant Binding Proteins in Modern Technology
BioFactors, Volume 52, Issue 1, January/February 2026.This review delves into bioinspired olfactory biosensors, focusing on insect odorant binding proteins (OBPs) as core elements of hybrid bionic platforms for volatile compound detection. Highlighting the development of the biological electronic nose (BE‐NOSE), it examines current prototypes, outlines advantages over conventional methods, and explores ...
Maddalena Ventura +5 more
wiley +1 more source
Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.In vitro trypanocidal activity of a polyprenylated benzophenone‐enriched Brazilian red propolis extract (SEBz) and its major constituents, guttiferone E/xanthochymol (GUT/XAN) and oblongifolin B (OBL), exhibit in vitro trypanocidal activity against Trypanosoma cruzi, inducing ultrastructural damage with moderate cytotoxicity and no significant ...
Nicoli Dias Oliveira +9 more
wiley +1 more source