Results 161 to 170 of about 515,233 (262)

Large‐Scale Chemoenzymatic Synthesis of a Glycophorin A Tetrasaccharide Motif and Its Analogues

open access: yesAsian Journal of Organic Chemistry, Volume 14, Issue 8, August 2025.
A large‐scale chemoenzymatic method was developed to synthesize natural and modified analogues of the Glycophorin A tetrasaccharide with either C9 or C5 terminal α‐2,3‐sialic acid variants. Selective α‐2,6‐sialylation of galactosamine was achieved by maintaining acetylation of the galactose during the course of enzymatic reactions. The products can aid
Ivan A. Gagarinov   +5 more
wiley   +1 more source

Computing Substrates and Life

open access: yes, 2006
Alive matter distinguishes itself from inanimate matter by actively maintaining a high degree of inhomogenous organisation. Information processing is quintessential to this capability.
Gunji, Yukio-Pegio   +2 more
core  

Robert Koch, Creation, and the Specificity of Germs [PDF]

open access: yes, 2010
Microbiology is dominated by evolution today. Just look at any text, journal article, or the topics presented at professional scientific meetings. Darwin is dominant. Microbiology is dominated by evolution today.
Gillen, Alan L.   +2 more
core   +1 more source

The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 8, August 2025.
Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He   +11 more
wiley   +1 more source

Exploration of Fluorinated Peptoid‐Based Histone Deacetylase Inhibitors as Dual‐Stage Antiplasmodial Agents

open access: yesArchiv der Pharmazie, Volume 358, Issue 8, August 2025.
The antiplasmodial properties of a series of fluorinated peptoid‐based histone deacetylase (HDAC) inhibitors were evaluated by screening them for their activity against asexual blood and liver stage malaria parasites and assessing their mammalian cell toxicity, to elucidate structure–activity and structure‐toxicity relationships. Compound 1h emerged as
Nina Reßing   +6 more
wiley   +1 more source

Sustainable control of Anopheles mosquito population [PDF]

open access: yes, 2014
Despite the widespread use of insecticides, community engagement programmes and preventive measures mosquito borne diseases are growing and new tools to prevent the spread of disease are urgently needed. An alternative control measure for the eradication
Birch, Philip   +5 more
core   +1 more source

Probabilistic single‐particle cryo‐EM ab initio 3D reconstruction in SIMPLE

open access: yesActa Crystallographica Section D, Volume 81, Issue 8, Page 396-409, August 2025.
We introduce a new approach to probabilistic multi‐volume single‐particle cryo‐EM ab initio 3D reconstruction for simultaneous estimation of the relative particle 3D orientations and partitioning of the particles into groups with distinct structural states.Three‐dimensional (3D) structure determination by single‐particle analysis of cryo‐electron ...
Cong T. S. Van   +11 more
wiley   +1 more source

Slime mould computes planar shapes [PDF]

open access: yes, 2011
Computing a polygon defining a set of planar points is a classical problem of modern computational geometry. In laboratory experiments we demonstrate that a concave hull, a connected alpha-shape without holes, of a finite planar set is approximated by ...
Adamatzky, Andrew
core  

A Short‐Read Amplicon Sequencing Protocol and Bioinformatic Pipeline for Ecological Surveillance of Dipteran Disease Vectors

open access: yesMolecular Ecology Resources, Volume 25, Issue 6, August 2025.
ABSTRACT Vector control remains an important strategy worldwide to prevent human infection with pathogens transmitted by arthropods. Vector control strategies rely on accurate identification of vector taxa along with vector‐specific biological indicators such as feeding ecology, infection prevalence and insecticide resistance.
Raquel Lima‐Cordón   +18 more
wiley   +1 more source

An Essential Fringe‐Like Protein in the Plasmodium falciparum Asexual Life Cycle

open access: bronze, 2020
Alejandra Villegas   +2 more
openalex   +1 more source

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