Results 41 to 50 of about 515,233 (262)

Arsinothricin Inhibits Plasmodium falciparum Proliferation in Blood and Blocks Parasite Transmission to Mosquitoes

open access: yesMicroorganisms, 2023
Malaria, caused by Plasmodium protozoal parasites, remains a leading cause of morbidity and mortality. The Plasmodium parasite has a complex life cycle, with asexual and sexual forms in humans and Anopheles mosquitoes.
Masafumi Yoshinaga   +6 more
doaj   +1 more source

Conserved RNA Binding Activity of Phosphatidyl Inositol 5-Phosphate 4-Kinase (PIP4K2A)

open access: yesFrontiers in Molecular Biosciences, 2021
Plasmodium falciparum is a causative agent for malaria and has a complex life cycle in human and mosquito hosts. During its life cycle, the malarial parasite Plasmodium goes through different asexual and sexual stages, in humans and mosquitoes ...
Jatin Behari   +12 more
doaj   +1 more source

An epithelial serine protease, AgESP, is required for Plasmodium invasion in the mosquito Anopheles gambiae. [PDF]

open access: yesPLoS ONE, 2012
Plasmodium parasites need to cross the midgut and salivary gland epithelia to complete their life cycle in the mosquito. However, our understanding of the molecular mechanism and the mosquito genes that participate in this process is still very limited ...
Janneth Rodrigues   +6 more
doaj   +1 more source

Protein Prenylation and Hsp40 in Thermotolerance of Plasmodium falciparum Malaria Parasites

open access: yesmBio, 2021
During its complex life cycle, the malaria parasite survives dramatic environmental stresses, including large temperature shifts.
Emily S. Mathews   +2 more
doaj   +1 more source

Activation of the hypnozoite: a part of Plasmodium vivax life cycle and survival [PDF]

open access: yesMalaria Journal, 2011
Plasmodium vivax is the most widespread malaria parasite. It has a dormant stage in the human liver, which makes it difficult to eradicate. It is proposed that a relapse of vivax malaria, besides being genetically determined by the specific strain, is induced by the bites of uninfected vectors.The dormant stage maximizes the possibility for the ...
Lena Hulden, Larry Huldén
openaire   +3 more sources

Plasmodium Reproduction, Cell Size, and Transcription: How to Cope With Increasing DNA Content?

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Plasmodium, the unicellular parasite that causes malaria, evolved a highly unusual mode of reproduction. During its complex life cycle, invasive or transmissive stages alternate with proliferating stages, where a single parasite can produce tens of ...
Marta Machado   +3 more
doaj   +1 more source

A divergent cyclin/cyclin-dependent kinase complex controls the atypical replication of a malaria parasite during gametogony and transmission

open access: yeseLife, 2020
Cell cycle transitions are generally triggered by variation in the activity of cyclin-dependent kinases (CDKs) bound to cyclins. Malaria-causing parasites have a life cycle with unique cell-division cycles, and a repertoire of divergent CDKs and cyclins ...
Aurélia C Balestra   +17 more
doaj   +1 more source

Checks and balances? DNA replication and the cell cycle in Plasmodium

open access: yesParasites & Vectors, 2018
It is over 100 years since the life-cycle of the malaria parasite Plasmodium was discovered, yet its intricacies remain incompletely understood - a knowledge gap that may prove crucial for our efforts to control the disease.
Holly Matthews   +2 more
doaj   +1 more source

Probing Plasmodium falciparum sexual commitment at the single-cell level [PDF]

open access: yes, 2018
Background: Malaria parasites go through major transitions during their complex life cycle, yet the underlying differentiation pathways remain obscure.
Birren, Bruce W.   +8 more
core   +4 more sources

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