Results 1 to 10 of about 1,191,103 (227)

Top-down inputs enhance orientation selectivity in neurons of the primary visual cortex during perceptual learning. [PDF]

, 2014
Perceptual learning has been used to probe the mechanisms of cortical plasticity in the adult brain. Feedback projections are ubiquitous in the cortex, but little is known about their role in cortical plasticity.
Bazhenov, Maxim, Moldakarimov, Samat, Sejnowski, Terrence J   +2 more
core   +20 more sources

Sustained postsynaptic kainate receptor activation downregulates AMPA receptor surface expression and induces hippocampal LTD

iScience, 2021
Summary: It is well established that long-term depression (LTD) can be initiated by either NMDA or mGluR activation. Here we report that sustained activation of GluK2 subunit-containing kainate receptors (KARs) leads to α-amino-3-hydroxy-5-methyl-4 ...
Jithin D. Nair, Ellen Braksator, Busra P. Yucel, Alexandra Fletcher-Jones, Richard Seager, Jack R. Mellor, Zafar I. Bashir, Kevin A. Wilkinson, Jeremy M. Henley   +8 more
doaj   +1 more source

Plasticity, plasticity, plasticity…and the rigid problem of sex [PDF]

Trends in Cognitive Sciences, 2013
Why is popular understanding of female–male differences still based on rigid models of development, even though contemporary developmental sciences emphasize plasticity? Is it because the science of sex differences still works from the same rigid models?
Fine, Cordelia, Jordan-Young, Rebecca, Kaiser, Anelis C., Rippon, Gina   +3 more
openaire   +4 more sources

The Bergen 4-day treatment for panic disorder: adapting to COVID-19 restrictions with a hybrid approach of face-to-face and videoconference modalities

BMC Psychiatry, 2023
Background The Bergen 4-day treatment (B4DT) is a concentrated exposure-based therapy that has been shown to be effective in the treatment of anxiety disorders.
Kay Morten Hjelle, Thorstein Olsen Eide, Anders Lillevik Thorsen, Gerd Kvale, Kristen Hagen, Ivar Snorrason, Thröstur Björgvinsson, Bjarne Hansen   +7 more
doaj   +1 more source

Online conversion of reconstructed neural morphologies into standardized SWC format

Nature Communications, 2023
Digital reconstructions provide an accurate and reliable way to store, share, model, quantify, and analyze neural morphology. Continuous advances in cellular labeling, tissue processing, microscopic imaging, and automated tracing catalyzed a ...
Ketan Mehta, Bengt Ljungquist, James Ogden, Sumit Nanda, Ruben G. Ascoli, Lydia Ng, Giorgio A. Ascoli   +6 more
doaj   +1 more source

Plasticity and dystonia: a hypothesis shrouded in variability. [PDF]

, 2020
Studying plasticity mechanisms with Professor John Rothwell was a shared highlight of our careers. In this article, we discuss non-invasive brain stimulation techniques which aim to induce and quantify plasticity, the mechanisms and nature of their ...
A Albanese, A Berardelli, A Conte, A Guerra, A Guerra, A Karabanov, A Karabanov, A Latorre, A Quartarone, A Quartarone, A Quartarone, A Quartarone, A Quartarone, A Quartarone, A Sadnicka, A Sadnicka, A Sadnicka, Anna Sadnicka, B Balint, B Cheeran, B Hordacre, C Ganos, C Terranova, D Belvisi, D Weise, F Fratello, F Pierelli, G Abbruzzese, H Eggink, HA Jinnah, HR Siebner, JF Muller-Dahlhaus, JS Kang, K Stefan, KM Fedak, KP Bhatia, L Ozelius, M Hamada, M Hamada, M Kojovic, M Pellegrini, Masashi Hamada, MC Ridding, N Patel, NH Jung, RG Carson, S Meunier, S Wiethoff, SA Schneider, V Lopez-Alonso, V Lopez-Alonso, YZ Huang, YZ Huang   +52 more
core   +1 more source

The Plastic Pancreas [PDF]

Developmental Cell, 2013
Pancreas homeostasis is based on replication of differentiated cells in order to maintain proper organ size and function under changing physiological demand. Recent studies suggest that acinar cells, the most abundant cell type in the pancreas, are facultative progenitors capable of reverting to embryonic-like multipotent progenitor cells under injury ...
Oren Ziv, Benjamin Glaser, Yuval Dor
openaire   +3 more sources

Changes in pallidal neural activity following long-term symptom improvement from botulinum toxin treatment in DYT6 dystonia: a case report

Journal of Medical Case Reports, 2022
Background The globus pallidus internus is the main target for the treatment of dystonia by deep brain stimulation. Unfortunately, for some genetic etiologies, the therapeutic outcome of dystonia is less predictable.
Andrea Giorni, Terry Coyne, Peter A. Silburn, George D. Mellick, Pankaj Sah, François Windels   +5 more
doaj   +1 more source

Tool use induces complex and flexible plasticity of human body representations [PDF]

, 2012
Plasticity of body representation fundamentally underpins human tool use. Recent studies have demonstrated remarkably complex plasticity of body representation in humans, showing that such plasticity: (1) occurs flexibly across multiple time-scales, and (
Longo, Matthew R., Serino, A.
core   +1 more source

Reduction in the activity of VTA/SNc dopaminergic neurons underlies aging-related decline in novelty seeking

Communications Biology, 2023
Curiosity, or novelty seeking, is a fundamental mechanism motivating animals to explore and exploit environments to improve survival, and is also positively associated with cognitive, intrapersonal and interpersonal well-being in humans.
Qiang Shan, Ye Tian, Hang Chen, Xiaoli Lin, Yao Tian   +4 more
doaj   +1 more source