Results 1 to 10 of about 529,998 (150)
iScience, 2021 Summary: It is well established that long-term depression (LTD) can be initiated by either NMDA or mGluR activation. Here we report that sustained activation of GluK2 subunit-containing kainate receptors (KARs) leads to α-amino-3-hydroxy-5-methyl-4 ...
Jithin D. Nair +8 more
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Online conversion of reconstructed neural morphologies into standardized SWC format
Nature Communications, 2023 Digital reconstructions provide an accurate and reliable way to store, share, model, quantify, and analyze neural morphology. Continuous advances in cellular labeling, tissue processing, microscopic imaging, and automated tracing catalyzed a ...
Ketan Mehta +6 more
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BMC Psychiatry, 2023 Background The Bergen 4-day treatment (B4DT) is a concentrated exposure-based therapy that has been shown to be effective in the treatment of anxiety disorders.
Kay Morten Hjelle +7 more
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Journal of Medical Case Reports, 2022 Background The globus pallidus internus is the main target for the treatment of dystonia by deep brain stimulation. Unfortunately, for some genetic etiologies, the therapeutic outcome of dystonia is less predictable.
Andrea Giorni +5 more
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Communications Biology, 2023 Curiosity, or novelty seeking, is a fundamental mechanism motivating animals to explore and exploit environments to improve survival, and is also positively associated with cognitive, intrapersonal and interpersonal well-being in humans.
Qiang Shan +4 more
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Physical but not virtual presence of others potentiates implicit and explicit learning
Scientific Reports, 2022 E-learning activities are becoming more and more common. Whilst it is well known that the physical presence of others motivates individuals to engage in perceptual and learning tasks, systematic investigations comparing the effects of physical and ...
Pietro Sarasso +8 more
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Neuromodulation of the feedforward dentate gyrus-CA3 microcircuit
Frontiers in Synaptic Neuroscience, 2016 The feedforward dentate gyrus-CA3 microcircuit in the hippocampus is thought to activate ensembles of CA3 pyramidal cells and interneurons to encode and retrieve episodic memories.
Luke Yuri Prince +3 more
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Regenerative neurogenic response from glia requires insulin-driven neuron-glia communication
eLife, 2021 Understanding how injury to the central nervous system induces de novo neurogenesis in animals would help promote regeneration in humans. Regenerative neurogenesis could originate from glia and glial neuron-glia antigen-2 (NG2) may sense injury-induced ...
Neale J Harrison +8 more
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Exploratory drive, fear, and anxiety are dissociable and independent components in foraging mice
Translational Psychiatry, 2021 Anxiety-like behavior of rodents is frequently accompanied by reduced exploration. Here, we identify dissociable components of anxiety, fear, and exploratory drive of sated and foraging mice.
Daniel E. Heinz +6 more
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GluK2 Q/R editing regulates kainate receptor signaling and long-term potentiation of AMPA receptors
iScience, 2023 Summary: Q/R editing of the kainate receptor (KAR) subunit GluK2 radically alters recombinant KAR properties, but the effects on endogenous KARs in vivo remain largely unexplored.
Jithin D. Nair +6 more
doaj +1 more source