Results 1 to 10 of about 1,157,325 (345)

Online conversion of reconstructed neural morphologies into standardized SWC format

open access: yesNature Communications, 2023
Digital reconstructions provide an accurate and reliable way to store, share, model, quantify, and analyze neural morphology. Continuous advances in cellular labeling, tissue processing, microscopic imaging, and automated tracing catalyzed a ...
Ketan Mehta   +6 more
doaj   +1 more source

The Bergen 4-day treatment for panic disorder: adapting to COVID-19 restrictions with a hybrid approach of face-to-face and videoconference modalities

open access: yesBMC Psychiatry, 2023
Background The Bergen 4-day treatment (B4DT) is a concentrated exposure-based therapy that has been shown to be effective in the treatment of anxiety disorders.
Kay Morten Hjelle   +7 more
doaj   +1 more source

Reduction in the activity of VTA/SNc dopaminergic neurons underlies aging-related decline in novelty seeking

open access: yesCommunications Biology, 2023
Curiosity, or novelty seeking, is a fundamental mechanism motivating animals to explore and exploit environments to improve survival, and is also positively associated with cognitive, intrapersonal and interpersonal well-being in humans.
Qiang Shan   +4 more
doaj   +1 more source

Changes in pallidal neural activity following long-term symptom improvement from botulinum toxin treatment in DYT6 dystonia: a case report

open access: yesJournal of Medical Case Reports, 2022
Background The globus pallidus internus is the main target for the treatment of dystonia by deep brain stimulation. Unfortunately, for some genetic etiologies, the therapeutic outcome of dystonia is less predictable.
Andrea Giorni   +5 more
doaj   +1 more source

Physical but not virtual presence of others potentiates implicit and explicit learning

open access: yesScientific Reports, 2022
E-learning activities are becoming more and more common. Whilst it is well known that the physical presence of others motivates individuals to engage in perceptual and learning tasks, systematic investigations comparing the effects of physical and ...
Pietro Sarasso   +8 more
doaj   +1 more source

Neuromodulation of the feedforward dentate gyrus-CA3 microcircuit

open access: yesFrontiers in Synaptic Neuroscience, 2016
The feedforward dentate gyrus-CA3 microcircuit in the hippocampus is thought to activate ensembles of CA3 pyramidal cells and interneurons to encode and retrieve episodic memories.
Luke Yuri Prince   +3 more
doaj   +1 more source

Regenerative neurogenic response from glia requires insulin-driven neuron-glia communication

open access: yeseLife, 2021
Understanding how injury to the central nervous system induces de novo neurogenesis in animals would help promote regeneration in humans. Regenerative neurogenesis could originate from glia and glial neuron-glia antigen-2 (NG2) may sense injury-induced ...
Neale J Harrison   +8 more
doaj   +1 more source

Whole-brain tracking of cocaine and sugar rewards processing

open access: yesTranslational Psychiatry, 2023
Natural rewards, such as food, and sex are appetitive stimuli available for animals in their natural environment. Similarly, addictive rewards such as drugs of abuse possess strong, positive valence, but their action relies on their pharmacological ...
Łukasz Bijoch   +7 more
doaj   +1 more source

Exploratory drive, fear, and anxiety are dissociable and independent components in foraging mice

open access: yesTranslational Psychiatry, 2021
Anxiety-like behavior of rodents is frequently accompanied by reduced exploration. Here, we identify dissociable components of anxiety, fear, and exploratory drive of sated and foraging mice.
Daniel E. Heinz   +6 more
doaj   +1 more source

Characterization of astrocytes throughout life in wildtype and APP/PS1 mice after early-life stress exposure

open access: yesJournal of Neuroinflammation, 2020
Background Early-life stress (ES) is an emerging risk factor for later life development of Alzheimer’s disease (AD). We have previously shown that ES modulates amyloid-beta pathology and the microglial response to it in the APPswe/PS1dE9 mouse model ...
Maralinde R. Abbink   +7 more
doaj   +1 more source

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