Results 31 to 40 of about 493,519 (313)

LRP4 is required for the olfactory association task in the piriform cortex

open access: yesCell & Bioscience, 2022
Background Low-density lipoprotein receptor-related protein 4 (LRP4) plays a critical role in the central nervous system (CNS), including hippocampal synaptic plasticity, maintenance of excitatory synaptic transmission, fear regulation, as well as long ...
Min Yan   +12 more
doaj   +1 more source

Plasticity

open access: yes, 2020
Although the expression πλαστική τέχνη [plastic art] has Greek origins, the derivative term “plasticity” enters the European languages only in the Modern Age. The term has a double meaning: it indicates, at the same time, the art of manipulating a ductile substance and the ability to transform oneself to recreate formal qualities in response to ...
openaire   +3 more sources

Plasticity and Anxiety [PDF]

open access: yesNeural Plasticity, 2007
Anxiety is a very broad behavioural trait, helping animals to cope with dangerous environmental situations. As anxiety is linked to other emotional processes and to cognitive functions such as learning and memory, it involves a number of cerebral structures and brain transmitter systems, thereby giving rise to a high degree of plasticity.
Georges Chapouthier, Patrice Venault
openaire   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Long-term follow-up of the Bergen 4-day treatment for panic disorder during the COVID-19 pandemic

open access: yesCogent Psychology
The COVID-19 pandemic has necessitated essential modifications to the administration of psychotherapy for patients with panic disorder (PD) through the increased use of videoconferencing.
Kay Morten Hjelle   +7 more
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Neurochemical changes in basal ganglia affect time perception in parkinsonians

open access: yesJournal of Biomedical Science, 2018
Background Parkinson’s disease is described as resulting from dopaminergic cells progressive degeneration, specifically in the substantia nigra pars compacta that influence the voluntary movements control, decision making and time perception.
Francisco Magalhães   +13 more
doaj   +1 more source

Beyond the Microbiota: Understanding the Role of the Enteric Nervous System in Parkinson’s Disease from Mice to Human

open access: yesBiomedicines, 2023
The enteric nervous system (ENS) is a nerve network composed of neurons and glial cells that regulates the motor and secretory functions of the gastrointestinal (GI) tract.
Martina Montanari   +4 more
doaj   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

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