Results 1 to 10 of about 1,076,997 (372)
To hydrolyze or not to hydrolyze: the dilemma of platelet-activating factor acetylhydrolase
Journal of Lipid Research, 2014 Mounting ambiguity persists around the functional role of the plasma form of platelet-activating factor acetylhydrolase (PAF-AH). Because PAF-AH hydrolyzes PAF and related oxidized phospholipids, it is widely accepted as an anti-inflammatory enzyme.
Gopal Kedihitlu Marathe +5 more
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Macrophage Derived Platelet Activating Factor Implicated in the Resolution Phase of Gouty Inflammation [PDF]
International Journal of Inflammation, 2014 Human blood derived in vitro differentiated monocytes or macrophages are a population of cells which have been investigated over the years to determine the role these cells play in the resolution phase of gout.
Darshna Yagnik
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Impact of targeting the platelet-activating factor and its receptor in cancer treatment [PDF]
Military Medical ResearchThe lipid mediator platelet-activating factor (PAF) and its receptor (PAFR) signaling play critical roles in a wide range of physiological and pathophysiological conditions, including cancer growth and metastasis.
Kimya Qaderi +3 more
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Platelet activating factor in allergies
International Journal of Immunopathology and Pharmacology, 2015 The platelet-activating factor (PAF) produced and released by mast cells, basophils, neutrophils, eosinophils, fibroblasts, platelets, endothelial cells, and even cardiac muscle cells plays an important role in inflammatory and thrombotic diseases. PAF has been shown to be an important mediator in anaphylaxis. Serum level of the factor correlates with
Krzysztof, Pałgan, Zbigniew, Bartuzi
openaire +3 more sources
Platelet activating factor revisited [PDF]
Thorax, 1997 8A2 and acetyltransferase on membrane alkylacyl phospholipids. PAF was found to possess many properties that made it well suited as a proinflammatory mediator of inflammation in many inflammatory diseases. 1 Interest in Degradation of PAF its potential role as a mediator of asthma was fuelled Being a potent bioactive mediator, it makes sense that PAF ...
Kian Fan Chung
openalex +4 more sources
Advance in the pathogenesis of otitis media with effusion induced by platelet-activating factor. [PDF]
Sci ProgLiu W, Shi L, Feng Y.
europepmc +2 more sources
Platelet-Activating Factor Promotes the Development of Non-Alcoholic Fatty Liver Disease. [PDF]
Diabetes Metab Syndr Obes, 2022 Yin H, Shi A, Wu J.
europepmc +3 more sources
Hearts, 2021 The purpose of this literature review is to gain an overview of the role of platelet-activating factor (PAF) within each of the body systems and how it contributes to normal and pathophysiological states.
Nilank Shah, Karan Kumar, Nikeith Shah
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Cells, 2021 The platelet-activating factor receptor (PAFR) and its ligand (PAF) are important inflammatory mediators that are overexpressed in ovarian cancer. The receptor is an important player in ovarian cancer development.
Eileen Deuster +14 more
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UVB-Induced Microvesicle Particle Release and Its Effects on the Cutaneous Microenvironment
Frontiers in Immunology, 2022 Ultraviolet B radiation (UVB) has profound effects on human skin that results in a broad spectrum of immunological local and systemic responses and is the major cause of skin carcinogenesis.
Timothy C. Frommeyer +10 more
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