Results 61 to 70 of about 24,574 (253)

Inhibitory Effects of Phylligenin and Quebrachitol Isolated from Mitrephora vulpina on Platelet Activating Factor Receptor Binding and Platelet Aggregation

Molecules, 2010
Phylligenine, together with quebrachitol, stigmasterol and two aporphine alkaloids—oxoputerine and liriodenine—were isolated from the twigs of Mitrephora vulpina C.E.C. Fisch.
Khozirah Shaari, Bushra Abdulkarim Moharam, Juriyati Jalil, Ibrahim Jantan   +3 more
doaj   +1 more source

Cancer therapy-induced PAFR ligand expression: any role for caspase activity? [PDF]

, 2017
No abstract ...
G Ichim, Gabriel Ichim, K Lauber, Q Huang, RP Sahu, RP Sahu, Stephen W. G. Tait, X Zhao   +7 more
core   +1 more source

Possible involvement of keratinocyte‐derived microvesicle particles in human photosensitivity disorders

Photochemistry and Photobiology, EarlyView.
In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju, Madison S. Owens, Anita Thyagarajan, Danielle A. Corbin, Catherine M. T. Sherwin, Jade Bryant, Garrett W. Fisher, Winston R. Owens, Alycia Ketter, Aadil Umerani, Craig A. Rohan, Michael G. Kemp, Robyn K. Crow, Jeffrey B. Travers   +13 more
wiley   +1 more source

Platelet Activating Factor Synthesis and Metabolism in Intestinal Ischaemia-Reperfusion Injury

Mediators of Inflammation, 1994
The object of this study was to characterize the synthesis and metabolism of platelet activating factor (PAF) by intestinal mucosa subjected to ischaemia–reperfusion injury.
M. J. Mangino, M. Murphy, A. Bohrer, J. Turk   +3 more
doaj   +1 more source

Effects of Platelet-Activating Factor on Brain Microvascular Endothelial Cells. [PDF]

, 2018
Platelet-activating factor (PAF) is a potent phospholipid mediator that exerts various pathophysiological effects by interacting with a G protein-coupled receptor.
Abood, Mary E., Barlow, Christine L., Brailoiu, Eugen, Brailoiu, G. Cristina, Ramirez, Servio H.   +4 more
core   +1 more source

Atrial fibrosis in atrial fibrillation: Mechanisms, mapping techniques and clinical applications

The Journal of Physiology, EarlyView.
Abstract figure legend Summary of key aspects of atrial fibrosis in atrial fibrillation, highlighting atrial fibrosis as a hallmark of atrial fibrillation (AF). (1) Different types of fibrosis (blue), illustrating reparative and reactive fibrosis; (2) fibrosis detection techniques (green), illustrating late gadolinium enhancement cardiac magnetic ...
Caterina Vidal Horrach, Laura Bevis, Cynthia Nwanna, Alexander M Zolotarev, Mahmoud Ehnesh, Semhar Biniam Misghina, Sayed Al‐Aidarous, Shohreh Honarbakhsh, Caroline H. Roney   +8 more
wiley   +1 more source

Clinical significance of plasma PAF acetylhydrolase activity measurements as a biomarker of anaphylaxis: Cross-sectional study.

PLoS ONE, 2021
IntroductionPlatelet-activating factor (PAF) has a direct role as a mediator in the pathogenesis of various disorders with an inflammatory component, including those with allergic aetiology.
Krzysztof Łukasz Piwowarek, Agnieszka Rzeszotarska, Jolanta Łukasz Korsak, Aleksandra Juszkiewicz, Andrzej Chciałowski, Jerzy Kruszewski   +5 more
doaj   +1 more source

Platelet-activating factor acetylhydrolase (PAF-AH) in human kidney

International Journal of Biochemistry, 1994
1. PAF-AH activity in human kidney (cortex and medulla) has been demonstrated and shares the following properties. 2. Does not require the presence of Ca2+ and appears to be different from phospholipase A2. 3. The pH optimum shows a peak at 7-7.4. 4. It is stable for 4 days at -30 degrees C. 5. It is mainly distributed in the microsomal fraction.
ANTONOPOULOU, S, DEMOPOULOS, CA, IATROU, C, MOUSTAKAS, G, ZIROGIANNIS, P   +4 more
openaire   +3 more sources

Phospholipid Profiling Established by Structure‐Rich Fragments for Molecular Species Level Shotgun Analysis

Rapid Communications in Mass Spectrometry, Volume 40, Issue 8, 30 April 2026.
ABSTRACT Rationale Accurate identification of phospholipid molecular species remains a major challenge in shotgun lipidomics because conventional tandem mass spectrometry typically resolves only one structural moiety at a time. This structural ambiguity limits confident lipid biomarker discovery and biological interpretation.
Rong Chen, Amber H. Jannasch, Bruce R. Cooper, Jonathan H. Shannahan, Christina R. Ferreira   +4 more
wiley   +1 more source

The emerging roles of PAF acetylhydrolase

Journal of Lipid Research, 2009
Platelet-activating factor (PAF), a phospholipid autacoid with potent effects throughout the innate immune system, is selectively degraded by two small families of PAF acetylhydrolases (PAF-AHs).
Thomas M. McIntyre, Stephen M. Prescott, Diana M. Stafforini   +2 more
doaj   +1 more source