Results 71 to 80 of about 24,574 (253)

The role of mucosal immunity in the pathogenesis of necrotizing enterocolitis [PDF]

open access: yes, 2017
Necrotizing enterocolitis (NEC) is the most devastating gastrointestinal disease of prematurity. Although the precise cause is not well understood, the main risk factors thought to contribute to NEC include prematurity, formula feeding, and bacterial ...
Bolock, Alexa M   +2 more
core   +2 more sources

Anti‐Inflammatory and Lipid Metabolism Modulatory Effects of Lantana camara L. Extract, With Enhanced Fibroblast Migration

open access: yesChemistry &Biodiversity, Volume 23, Issue 2, February 2026.
This graphical abstract represents the main results of the study. It highlights the plant species under investigation: Lantana camara L. ABSTRACT Inflammation is a complex process associated with various chronic diseases. Lantana camara L., widely used in traditional medicine, exhibits diverse bioactivities, though its effects on lipid metabolism ...
Ari S. de O. Lemos   +8 more
wiley   +1 more source

Inpatient Outcomes of Atrial Fibrillation in Patients With Acute Pancreatitis: Insights From the TriNetX Database

open access: yesJournal of Arrhythmia, Volume 42, Issue 1, February 2026.
There was a statistically significant increase in all cause mortality, patients requiring ICU level of care, acute kidney injury, deep venous thrombosis, hemorrhage, and severe sepsis in patients hospitalized for acute pancreatitis with atrial fibrillation as compared to those without atrial fibrillation between 2010 and 2024.
Obaid Ur Rehman   +9 more
wiley   +1 more source

A possible role for platelet-activating factor in the hydrogen peroxide-induced TXB2 and PGE2 glomerular synthesis.

open access: yesJournal of Lipid Research, 1995
Hydrogen peroxide stimulates both prostanoid and platelet-activating factor (PAF) biosynthesis in cultured rat mesangial cells and isolated rat glomeruli.
I Arribas-Gómez   +6 more
doaj   +1 more source

Synthetic studies on platelet-activating factor (PAF).

open access: yesChemical and Pharmaceutical Bulletin, 1985
Chemical synthesis of platelet-activating factor (PAF, 1) and its enantiomer was studied. Several alkoxymethyl alkenyl ketones (5a-c, n=14 or 16) were synthesized from Wittig-Horner reagents (4, n=14 or 16) with cyclohexanecarboxaldehyde, octylaldehyde, and benzaldehyde, and subjected to asymmetric reduction with BINAL-H1) which is known to show high ...
H, Suemune, A, Akashi, K, Sakai
openaire   +3 more sources

Expanding the Immunologic and Neuronal Landscape of IgE‐Mediated Anaphylaxis

open access: yesImmunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Anaphylaxis is a life‐threatening immunoglobulin E (IgE)‐mediated type I hypersensitivity reaction with rising prevalence and burden. It involves mast cell degranulation upon cross‐linking of antigen on mast cell‐bound IgE. Mechanisms of IgE‐mediated anaphylaxis remain incompletely understood, particularly the induction of systemic symptoms ...
Ruchi Biswas   +2 more
wiley   +1 more source

Is platelet activating factor (PAF) an important mediator in bronchial asthma?

open access: yesMediators of Inflammation, 1992
The development of selective PAF receptor antagonists may provide a novel approach to the treatment of human bronchial asthma. In preclinical animal models of human asthma, PAF receptor antagonists have been found to be efficacious in blocking antigen ...
R. H. Gundel, H. O. Heuer, L. G. Letts
doaj   +1 more source

Tricarboxylic Acid Cycle Activity and Remodeling of Glycerophosphocholine Lipids Support Cytokine Induction in Response to Fungal Patterns

open access: yesCell Reports, 2019
Summary: Increased glycolysis parallels immune cell activation, but the role of pyruvate remains largely unexplored. We found that stimulation of dendritic cells with the fungal surrogate zymosan causes decreases of pyruvate, citrate, itaconate, and α ...
Saioa Márquez   +10 more
doaj   +1 more source

Gastrointestinal endogenous proteins as a source of bioactive peptides : Doctor of Philosophy in Nutritional Sciences at Riddet Institute, Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2016
Gastrointestinal endogenous proteins (GEP) were investigated as a source of bioactive peptides. In silico and in vitro methods were used singly or in combination to study GEP-derived peptides after simulated digestion.
Acharya, Prasannalakshmi
core  

Elevation of plasma phospholipid transfer protein increases the risk of atherosclerosis despite lower apolipoprotein B-containing lipoproteins. [PDF]

open access: yes, 2004
Plasma phospholipid transfer protein (PLTP) transfers phospholipids between lipoproteins and mediates HDL conversion. PLTP-overexpressing mice have increased atherosclerosis.
Arai   +47 more
core   +3 more sources

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