Results 81 to 90 of about 160,257 (342)

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

Dissecting Bacterial Cell Wall Entry and Signaling in Eukaryotic Cells: an Actin-Dependent Pathway Parallels Platelet-Activating Factor Receptor-Mediated Endocytosis

open access: yesmBio, 2017
The Gram-positive bacterial cell wall (CW) peptidoglycan-teichoic acid complex is released into the host environment during bacterial metabolism or death.
Lip Nam Loh   +2 more
doaj   +1 more source

Platelet-Activating Factor Receptor Contributes to Antileishmanial Function of Miltefosine [PDF]

open access: yesThe Journal of Immunology, 2015
Abstract Miltefosine [hexadecylphosphocholine (HPC)] is the only orally bioavailable drug for the disease visceral leishmaniasis, which is caused by the protozoan parasite Leishmania donovani. Although miltefosine has direct leishmanicidal effects, evidence is mounting for its immune system–dependent effects.
Pallavi R, Gangalum   +7 more
openaire   +2 more sources

Emerging 2D Materials and Their Hybrid Nanostructures for Label‐Free Optical Biosensing: Recent Progress and Outlook

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in label‐free optical biosensors based on 2D materials and rationally designed mixed‐dimensional nanohybrids, emphasizing their synergistic effects and novel functionalities. It also discusses multifunctional sensing platforms and the integration of machine learning for intelligent data analysis.
Xinyi Li, Yonghao Fu, Yuehe Lin, Dan Du
wiley   +1 more source

Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]

open access: yes, 2006
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Siess, Wolfgang
core   +1 more source

Inducing Chirality and Chiral Instabilities in Ferrogels with Homogenous Magnetic Fields

open access: yesAdvanced Functional Materials, EarlyView.
By pre‐aligning magnetic particles into chains, significant chiral deformations are induced by fixing the base of a cylindrical actuator and applying a homogeneous magnetic field. Subsequent base rotation can drive the system into metastable states. Further rotation or reduction of field strength triggers a chiral instability, characterized by a switch
Francisco J. Vazquez‐Perez   +4 more
wiley   +1 more source

An immune-adrenergic pathway induces lethal levels of platelet-activating factor in mice

open access: yesCommunications Biology
Acute immune responses with excess production of cytokines, lipid/chemical mediators, or coagulation factors, often result in lethal damage. In addition, the innate immune system utilizes multiple types of receptors that recognize neurotransmitters as ...
Shuto Tanaka   +14 more
doaj   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee   +4 more
wiley   +1 more source

Molecular and Genetic Determinants of Glioma Cell Invasion. [PDF]

open access: yes, 2017
A diffusely invasive nature is a major obstacle in treating a malignant brain tumor, "diffuse glioma", which prevents neurooncologists from surgically removing the tumor cells even in combination with chemotherapy and radiation.
Kato, Yoichiro   +4 more
core   +5 more sources

Airway epithelial platelet-activating factor receptor expression is markedly upregulated in chronic obstructive pulmonary disease

open access: yesInternational Journal of COPD, 2014
Shakti Dhar Shukla,1,* Sukhwinder Singh Sohal,1,* Malik Quasir Mahmood,1 David Reid,2 Hans Konrad Muller,1 Eugene Haydn Walters1 1NHMRC Centre for Research Excellence for Chronic Respiratory Disease and Lung Ageing, School of Medicine, University of ...
Shukla SD   +5 more
doaj  

Home - About - Disclaimer - Privacy