Results 41 to 50 of about 1,624,972 (407)
Fibrinogen Mitigates Prion-Mediated Platelet Activation and Neuronal Cell Toxicity
Frontiers in Cell and Developmental Biology, 2022 Prion peptide (PrP) misfolds to infectious scrapie isoform, the β pleat-rich insoluble fibrils responsible for neurodegeneration and fatal conformational diseases in humans.
Deepa Gautam +7 more
doaj +1 more source
Oral platelet gel supernatant plus supportive medical treatment versus supportive medical treatment in the management of radiation-induced oral mucositis: a matched explorative active control trial by propensity analysis [PDF]
, 2017 OBJECTIVES:: In this active control trial, the rate of radio-induced WHO grade 3/4 oral mucositis and the change in quality of life, assessed by OMWQ-HN, were measured in subjects with head and neck cancer treated by platelet gel supernatant (PGS) and ...
Bonfili P +15 more
core +1 more source
Molecular Genetics & Genomic Medicine, 2014 MYH9‐Related Disorders are a group of rare autosomal dominant platelet disorders presenting as nonsyndromic forms characterized by macrothrombocytopenia with giant platelets and leukocyte inclusion bodies or as syndromic forms combining these ...
Béatrice Saposnik +7 more
doaj +1 more source
Effects of High Flavanol Dark Chocolate on Cardiovascular Function and Platelet Aggregation. [PDF]
, 2015 Regular consumption of chocolate and cocoa products has been linked to reduced cardiovascular mortality. This study compared the effects of high flavanol dark chocolate (HFDC; 1064mg flavanols/day for 6 weeks) and low flavanol dark chocolate (LFDC; 88mg ...
Akita +56 more
core +1 more source
Platelets, 2021 Platelets play an essential role in maintaining vascular integrity after injury. In addition, platelets contribute to the immune response to pathogens. For instance, they express receptors that mediate binding of viruses, and toll-like receptors that activate the cell in response to pathogen-associated molecular patterns.
Silvio Antoniak, Nigel Mackman
openaire +4 more sources
Randomized Trial of Platelet‐Transfusion Thresholds in Neonates
New England Journal of Medicine, 2019 BACKGROUND Platelet transfusions are commonly used to prevent bleeding in preterm infants with thrombocytopenia. Data are lacking to provide guidance regarding thresholds for prophylactic platelet transfusions in preterm neonates with severe ...
A. Curley +19 more
semanticscholar +1 more source
Bleeding, Thrombosis and Vascular Biology, 2023 The platelet collagen receptor glycoprotein VI (GPVI) signals to activation of phospholipase Cγ2 (PLCγ2) and phosphoinositide 3-kinases (PI3K), causing platelet activation and aggregation.
Jingnan Huang +5 more
doaj +1 more source
Platelet monoamine oxidase activity in alcoholics with and without a family history of alcoholism [PDF]
, 2000 A number of studies point at platelet monoamine oxidase (MAO) activity being reduced in alcoholics with a family history of drinking, this being a possible vulnerability marker for alcoholism.
Benda, Ellen +5 more
core +1 more source
The Lancet, 2007 Ever since platelet transfusions were shown to reduce mortality from haemorrhage in patients with acute leukaemia in the 1950s, the use of this therapy has steadily grown to become an essential part of the treatment of cancer, haematological malignancies, marrow failure, and haematopoietic stem cell transplantation.
Stroncek, David F., Rebulla, Paolo
openaire +3 more sources
Blood, 2019 Aging and chronic inflammation are independent risk factors for the development of atherothrombosis and cardiovascular disease. We hypothesized that aging-associated inflammation promotes the development of platelet hyperreactivity and increases ...
Pavel Davizon-Castillo +24 more
semanticscholar +1 more source