Results 1 to 10 of about 478,140 (363)
Platelets, 2022 Platelet transfusion refractoriness is a serious clinical concern that complicates the management of thrombocytopenic patients. Previous studies have suggested a potential role for both complement and platelet activation based on in vitro analyses of ...
Alexander Åkesson +7 more
doaj +1 more source
Baseline Platelet Activation and Reactivity in Patients with Critical Limb Ischemia. [PDF]
PLoS ONE, 2015 Patients with critical limb ischemia (CLI) have a high risk to develop cardiovascular events (CVE). We hypothesized that in CLI patients platelets would display increased baseline activation and reactivity.We investigated baseline platelet activation and
Peter Paul Wisman +5 more
doaj +1 more source
C1-inhibitor influence on platelet activation by thrombin receptors agonists
Clinical and Applied Thrombosis/Hemostasis, 2022 Introduction Protease activated receptors 1 (PAR1) and 4 (PAR4) agonists are used to study platelet activation. Data on platelet activation are extrapolated across experimental settings.
Ivan D. Tarandovskiy PhD +2 more
doaj +1 more source
The Dynamics of Platelet Activation during the Progression of Streptococcal Sepsis. [PDF]
PLoS ONE, 2016 Platelets contribute to inflammation however, the role of platelet activation during the pathophysiological response to invasive bacterial infection and sepsis is not clear.
Sinead M Hurley +3 more
doaj +1 more source
Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 1985 Platelets are discoidal cytoplasmic particles that respond to a variety of stimuli by developing filopodia and rounding up (shape change), developing the ability to bind fibrinogen from the medium, and, with strong stimuli such as thrombin and PAF-acether, secreting the contents of several types of granules.
M B, Zucker, V T, Nachmias
openaire +2 more sources
Platelet Activation in Human Immunodeficiency Virus Type-1 Patients Is Not Altered with Cocaine Abuse. [PDF]
PLoS ONE, 2015 Recent work has indicated that platelets, which are anucleate blood cells, significantly contribute to inflammatory disorders. Importantly, platelets also likely contribute to various inflammatory secondary disorders that are increasingly associated with
Michelle Kiebala +5 more
doaj +1 more source
Zinc: an endogenous and exogenous regulator of platelet function during hemostasis and thrombosis
Platelets, 2021 Zinc (Zn2+) is an essential micronutrient and the second most abundant trace metal in the human body. The important role that Zn2+ plays in hemostasis is exemplified by platelet-related bleeding phenotypes coinciding with dietary Zn2+ deficiency.
Niaz Shahed Ahmed +2 more
doaj +1 more source
Application of an optimized flow cytometry-based quantification of Platelet Activation (PACT): Monitoring platelet activation in platelet concentrates. [PDF]
PLoS ONE, 2017 BACKGROUND:Previous studies have shown that flow cytometry is a reliable test to quantify platelet function in stored platelet concentrates (PC). It is thought that flow cytometry is laborious and hence expensive.
Cécile H Kicken +4 more
doaj +1 more source
Frontiers in Immunology, 2022 BackgroundChancre self-healing, a typical clinical phenomenon of primary syphilis, is essentially wound healing. The first response to a wound is constriction of the injured blood vessels and activation of platelets to form a fibrin clot.
Qiu-Yan Xu +9 more
doaj +1 more source
Preeclampsia and platelets activation
Platelets, 2019 Dear Sir,We found the metanalysis by Jakobsen et al. regarding the function of platelets in preeclampsia (PE) very interesting [1].
Antonio Ponzetto, Giovanna Turvani
openaire +5 more sources