A study of platelet activation in the antiphospholipid syndrome [PDF]
The association between thromboembolism and the presence of antiphospholipid antibodies (APA) is well established, however the mechanism of action of APA in the pathogenesis of thrombosis remains elusive.
Joseph, Joanne Emily
core
Proteases in Blood Platelets: Collagen Induced Activation of Proelastase by a Trypsin-Like Enzymes [PDF]
Y Legrand, J Caen
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Modeling Platelet P2Y$_1$/$_{12}$ Pathway to Integrin Activation [PDF]
Through experimental studies, many details of the pathway of integrin $\alpha_{\rm IIb}\beta_3$ activation by ADP during the platelet aggregation process have been mapped out. ADP binds to two separate G protein coupled receptors on platelet surfaces, leading to alterations in the regulation of the small GTPase RAP1.
arxiv
Inhibitory Effect of Aprotinin on the Activation Process of Contact Factors and Platelet Aggregation [PDF]
Isao Yamaguchi+6 more
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Movements of Calcium Ions and Their Role in the Activation of Platelets [PDF]
P. Massini+2 more
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Light-Activated Motion, Geometry- and Confinement-Induced Optical Effects of 2D Platelets in a Nematic Liquid Crystal [PDF]
Motile liquid crystal (LC) colloids show peculiar behavior due to the high sensitivity to external stimuli driven by the LC elastic and surface effects. However, few studies focus on harnessing the LC phase transitions to propel colloidal inclusions by the nematic-isotropic (NI) interface. We engineer a quasi-2D active system consisting of solid micron-
arxiv
The effects of arterial flow on platelet activation, thrombus growth, and stabilization [PDF]
Injury of an arterial vessel wall acutely triggers a multifaceted process of thrombus formation, which is dictated by the high-shear flow conditions in the artery. In this overview, we describe how the classical concept of arterial thrombus formation and
Angelillo-Scherrer, Anne+3 more
core
Studies on the mechanism of expression of secreted fibrinogen on the surface of activated human platelets [PDF]
C Legrand+2 more
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Platelets interact with fibrin only after activation [PDF]
RR Hantgan, RG Taylor, JC Lewis
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Background: Platelets, a type of anucleated cell, play a crucial role in cardiovascular diseases (CVDs). Therefore, targeting platelet activation is essential for mitigating CVDs.
Yi Chang+6 more
doaj +1 more source