Results 11 to 20 of about 10,369 (128)
Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT+28 more
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Platelets at the vascular interface [PDF]
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Bergmeier, Wolfgang, Stefanini, Lucia
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A Perspective of Coagulation Dysfunction in Multiple Sclerosis and in Experimental Allergic Encephalomyelitis [PDF]
A key role of both coagulation and vascular thrombosis has been reported since the first descriptions of multiple sclerosis (MS). Subsequently, the observation of a close concordance between perivascular fibrin(ogen) deposition and the occurrence of ...
Adams+158 more
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The influence of bevacizumab on platelet function
Systemic treatment with bevacizumab is associated with increased rates of arterial and venous thromboembolism and haemorrhage. In order to investigate the pathophysiological mechanism involved, platelet adhesive and aggregatory functions were tested
M Fehr+5 more
doaj +1 more source
Cardiovascular disease (CVD) is a major comorbidity in chronic obstructive pulmonary disease (COPD). Although the mechanism of its development remains largely unknown, it appears to be associated with cigarette consumption and reduced lung function ...
Patrice Marques+13 more
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IN-VIVO AND IN-VITRO EFFECTS OF POLYVINYLPYRROLIDONE ON PLATELET ADHESIVENESS IN HUMAN BLOOD [PDF]
Intravenous infusion of 500 ml. 6% polyvinylpyrrolidone (P.V.P. (Mw 40,000) in isotonic saline solution over a 2-hour period significantly diminished platelet adhesiveness in eight subjects from 27% before infusion to as low as 10% at the end of the ...
Sanbar, Shafeek S.+2 more
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RAP GTPases and platelet integrin signaling
Platelets are highly specialized cells that continuously patrol the vasculature to ensure its integrity (hemostasis). At sites of vascular injury, they are able to respond to trace amounts of agonists and to rapidly transition from an anti-adhesive ...
Lucia Stefanini, Wolfgang Bergmeier
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Background Abnormal adhesiveness of red blood cells to endothelium has been implicated in vaso-occlusive crisis of sickle cell disease. The present study examined whether the SAD mouse model exhibits the same abnormalities of red blood cell adhesion as ...
Marie-Marcelle Trinh-Trang-Tan+4 more
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Erythrocyte as a link between basic and clinical research [PDF]
© 2011 – IOS Press and the authorsWe review the major hemorheological experimental studies that show the erythrocyte aggregation as a link between basic and clinical research. The results of the clinical cross-sectional and longitudinal studies presented
Almeida, J. P. Lopes de, Saldanha, C.
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A LAD-III syndrome is associated with defective expression of the Rap-1 activator CalDAG-GEFI in lymphocytes, neutrophils, and platelets [PDF]
Leukocyte and platelet integrins rapidly alter their affinity and adhesiveness in response to various activation (inside-out) signals. A rare leukocyte adhesion deficiency (LAD), LAD-III, is associated with severe defects in leukocyte and platelet ...
Alon, Ronen+13 more
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