Protein disulfide isomerase (PDI), an oxidoreductase, possesses two vicinal cysteines in the -Cys-Gly-His-Cys-motif that either form a disulfide bridge (S–S) or exist in a sulfhydryl form (-SH), forming oxidized or reduced PDI, respectively. PDI has been
Lu Wang+6 more
doaj
The Influence of Haemoglobin A1c Levels on Platelet Aggregation and Platelet Turnover in Patients with Coronary Artery Disease Treated with Aspirin. [PDF]
Hyperglycaemia may attenuate the antiplatelet effect of aspirin and thereby increase the risk of cardiovascular events. We investigated the influence of increased haemoglobin A1c (HbA1c) levels on platelet aggregation and turnover in a large cohort of ...
Søs Neergaard-Petersen+5 more
doaj +1 more source
Effect of electrolyte on the microstructure and yielding of aqueous dispersions of colloidal clay [PDF]
Na-montmorillonite is a natural clay mineral and is available in abundance in nature. The aqueous dispersions of charged and anisotropic platelets of this mineral exhibit non-ergodic kinetically arrested states ranging from soft glassy phases dominated by interparticle repulsions to colloidal gels stabilized by salt induced attractive interactions ...
arxiv +1 more source
HUBUNGAN MEROKOK DENGAN AGREGASI TROMBOSIT PADA MAHASISWA DI LINGKUNGAN UNIVERSITAS DIPONEGORO [PDF]
Background : Smoking is a risk factor for several diseases. One of the important mechanisms involved is an atherothrombosis process. This process can be initiated by platelet aggregation.
Adhipireno, Purwanto, Mufidah, Aulia
core +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source
Colloid aggregation induced by oppositely charged polyions [PDF]
The "polymer reference interaction site model" (PRISM) integral equation formalism is used to determine the pair structure of binary colloidal dispersions involving large and small polyions of opposite charge. Two examples of such bidisperse suspensions are considered in detail, namely mixtures of charged spherical colloids and oppositely charged ...
arxiv +1 more source
Familial exudative vitreoretinopathy associated with familial thrombocytopathy. [PDF]
Two families with familial exudative vitreoretinopathy were studied in which platelet aggregation defects were found in all the affected members. The major defect observed was absent platelet aggregation with arachidonic acid.
A R Rosenthal+4 more
core +2 more sources
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld+7 more
wiley +1 more source
Nanoscale assembly processes revealed in the nacroprismatic transition zone of Pinna nobilis mollusc shells [PDF]
Intricate biomineralization processes in molluscs engineer hierarchical structures with meso-, nano-, and atomic architectures that give the final composite material exceptional mechanical strength and optical iridescence on the macroscale. This multiscale biological assembly inspires new synthetic routes to complex materials.
arxiv +1 more source
Elucidating the role of Staphylococcus epidermidis serine-aspartate repeat protein G in platelet activation. [PDF]
BACKGROUND: Staphylococcus epidermidis is a commensal of the human skin that has been implicated in infective endocarditis and infections involving implanted medical devices. S. epidermidis induces platelet aggregation by an unknown mechanism.
Arasu, S+6 more
core +2 more sources