Results 211 to 220 of about 218,065 (393)

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

Advanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu, Yumeng Yan, Meiling Zheng, Mina Zhang, Tengfei Chen, Zhicheng Qu, Yinglu Bai, Shuwen Zhang, Chunming Zhao, Yifan Shi, Yan Lin, Ning Wang, Yunjing Bai, Yating Zhai, Zhaofang Bai, Wei Guo, Qingquan Liu   +16 more
wiley   +1 more source

The Crucial Roles of Platelets as Immune Mediators in Sepsis. [PDF]

J Inflamm Res
Yang X, Song J, Ma H, Hua N, Bai Y, Ju Y, Shen JW, Zheng W, Jiang S.   +8 more
europepmc   +1 more source

Platelet aggregation inhibitors and inotropic constituents in Pyrolae herba.

Chemical and pharmaceutical bulletin, 1992
K. Kagawa, K. Tokura, K. Uchida, H. Kakushi, T. Shike, H. Nakai   +5 more
semanticscholar   +1 more source

The hepoxilin analog PBT‐3 inhibits heparin‐activated platelet aggregation evoked by ADP [PDF]

, 2002
Dénis Reynaud, Alexander Hinek, C.R. Pace-Asciak   +2 more
openalex   +1 more source

Nrf2 Drives Epigenetic Reprogramming and Acts as the Master Regulator of KLF4 Expression and Activity in Arsenic‐Induced Transformation

Advanced Science, EarlyView.
Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang, Zhuoyue Bi, Jessica Bamrah, Yiran Qiu, Wenxuan Zhang, Bandar Saeed Almutairy, Haoyan Ji, John D. Haley, Chitra Thakur, Fei Chen   +9 more
wiley   +1 more source

Casein kinase I isoforms contribute to platelet activation and thrombogenesis via RIPK3-MLKL signaling. [PDF]

Commun Biol
Singh V, Ekhlak M, Chaurasia SN, Dash D.
europepmc   +1 more source

Pyridazines. XIII. Synthesis of 6-aryl-5-oxygenated substituted-3(2H)-pyridazinones and evaluation as platelet aggregation inhibitors.

Chemical and pharmaceutical bulletin, 1997
R. Laguna, B. Rodríguez-Liñares, E. Cano, I. Estevez, E. Raviña, E. Sotelo   +5 more
semanticscholar   +1 more source

Angiotensin II AT ₁ Receptor Antagonists Inhibit Platelet Adhesion and Aggregation by Nitric Oxide Release [PDF]

, 2002
Leszek Kalinowski, Tomasz Matys, Ewa Chabielska, Włodzimierz Buczko, Tadeusz Maliñski   +4 more
openalex   +1 more source

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

Advanced Science, EarlyView.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao, Huailong An, Cong Fan, Qingsu Lan, Hongyu Zhong, Yun Zhang, Libo Zhou, Panpan Hao   +7 more
wiley   +1 more source

Potato lectin: a modular protein sharing sequence similarities with the extensin family, the hevein lectin family, and snake venom disintegrins (platelet aggregation inhibitors).

The Plant Journal, 1994
M. Kieliszewski, A. Showalter, J. Leykam
semanticscholar   +1 more source