Results 251 to 260 of about 54,964 (304)
Effect of Inhibitors of Aggregation on Platelet Ultrastructure in Vitro [PDF]
Thrombosis and Haemostasis, 1969 SummaryElectron microscopy observations are presented on the effect of inhibitors of aggregation on platelet morphology. Moreover the relationship existing between shape changes produced by inhibitors of platelet aggregation and the mechanism of inhibition has also been studied.Among the inhibitors, nucleotides were without effect on platelet shape, so
P M, Mannucci, F, Sirigu
openaire +3 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Thienopyrimidine-based P2Y12 platelet aggregation inhibitors
Bioorganic and Medicinal Chemistry Letters, 2009Herein we describe the design and synthesis of a novel series of potent thienopyrimidine P2Y12 inhibitors and the negative impact protein binding has on the inhibition of platelet aggregation.
Steven W, Kortum +7 more
exaly +3 more sources
Platelet aggregation inhibitors, vitamin K antagonists and risk of subarachnoid hemorrhage [PDF]
Journal of Thrombosis and Haemostasis, 2011 Background: Use of platelet aggregation inhibitors and vitamin K antagonists has been associated with an increased risk of intracranial hemorrhage (ICH).
R M C Herings, W J Niessen
exaly +4 more sources
Disposition of anagrelide, an inhibitor of platelet aggregation
Clinical Pharmacology and Therapeutics, 1981A single dose of 14C-anagrelide (6,7-dichloro-1,5-dihydroimidazo [2,1-b] quinazoline-2(3H)-one monohydrochloride) equivalent to 1 mg free base and containing 100 muCi radioactivity, was taken by five healthy, fasting men. Blood, plasma, urine, and feces were analyzed for total radioactivity. Plasma and urine concentrations of anagrelide were determined,
R C, Gaver +3 more
openaire +2 more sources
Prostaglandins as Inhibitors of Human Platelet Aggregation
British Journal of Haematology, 1979Summary. The potencies of prostaglandins (PG) I2, PGD2 and PGE1 as inhibitors of human platelet aggregation induced by threshold concentrations of four aggregating agents were determined in platelet‐rich plasma from normal individuals who had not ingested aspirin. The order of activity against ADP, adrenaline and collagen was always PGI2 > PGD2 >
DI MINNO, GIOVANNI +2 more
openaire +3 more sources
Platelet aggregation inhibitors in neurology
Pharmacy World & Science, 1993This literature review reports on secondary prevention of ischaemic stroke. The aim of secondary prevention is to protect patients who belong to a risk group from the occurrence of brain infarction. Symptomatic patients with a demonstrated carotid artery stenosis of 70% and more will most probably benefit from carotid endarterectomy if performed by a ...
openaire +2 more sources
Purification and characterization of platelet aggregation inhibitors from snake venoms [PDF]
Thrombosis Research, 1994 Proteins that inhibit glycoprotein (GP) IIb/IIIa mediated platelet aggregation have been purified from the venom of two snake species. A small platelet aggregation inhibitor (pl.AI), multisquamatin (Mr=5,700), was purified from Echis multisquamatus venom
Francis Markland +2 more
exaly +3 more sources
Hypopigmentation in Dogs Treated with an Inhibitor of Platelet Aggregation
Toxicologic Pathology, 1989Hypopigmentation was the principal manifestation of systemic toxicity when the experimental platelet aggregation inhibitor, PD-89454, was orally administered to Beagle dogs for 28 days. Pigmentation changes were present in skin of nose, lips and eyelids and mucosa of hard palate.
K M, Walsh, A W, Gough
openaire +2 more sources
PLATELET AGGREGATION INHIBITORS
2012Peptides and cyclized analogs thereof that are useful as platelet aggregation inhibitors in the treatment of cardiac disease, including acute coronary syndrome are disclosed.
Mrksich, Milan, Sanchez-Cortes, Juan
openaire +1 more source