Results 51 to 60 of about 327,494 (241)

Platelet adhesion in atherogenesis [PDF]

, 2010
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Master of PhilosophyPlatelets are known to play a key role in acute coronary events, such as myocardial infarction, associated with advanced
Watkins, Jennifer
core   +3 more sources

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Bacterial Contamination of Blood Products Stored at Room Temperature on Agitator in Lagos State, Nigeria

Journal of Preventive, Diagnostic and Treatment Strategies in Medicine
BACKGROUND: The relevance of some plasma-based medicinal products, especially platelet concentrates in modern medical care, is confirmed by their inclusion in the World Health Organization Essential Medicines.
Tesleemah Oluwakemi Davies-Folorunso, Musa Abidemi Muhibi, Jamiu Bello Folorunso, Olufemi David Olaniyi, Abdulwaheed Adewale Ademosun, Nuryn Abdulganiy, Yekeen Adebisi Kosamat, Phoebe Nwamaka Kanikwu, Bodunrin Ibitola Osikomaiya, Mathew Folaranmi Olaniyan   +9 more
doaj   +1 more source

Platelet Concentrates – A Panacea for Periodontal Regeneration

, 2023
Periodontitis is an inflammatory condition of the periodontium leading to loss of supporting structures of the tooth. The regeneration of periodontium refers to the restoration of the lost tissues to their original form and function by reiterating the ...
S, Pradhan, J, Shetty N
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Quality control in veterinary blood banks: evaluation of canine platelet concentrates stored for five days

BMC Veterinary Research, 2020
Background Platelets undergo structural, biochemical and functional alterations when stored, and platelet storage lesions reduce platelet function and half-life after transfusion.
Camila Serina Lasta, Nicole Hlavac, Natália Aydos Marcondes, Magnus Larruscaim Dalmolin, Silvia Resende Terra, Luciana de Almeida Lacerda, Gustavo Adolpho Moreira Faulhaber, Félix Hilário Díaz González   +7 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Evaluation of the quality of platelet concentrates obtained in a Peruvian hospital

Medwave
Introduction Platelet concentrates are blood products obtained from donor’s blood, and their conservation must be subject to a strict quality control process to guarantee a safe and high-performance product in treating diseases that require their use.
Jair Huamani-Chacchi, Fernando Soncco-Llulluy, Jaime Rosales-Rimache   +2 more
doaj   +1 more source

Comparison of changes in platelet count, mean platelet volume and swirling in stored platelet concentrates with and without platelet additive solution

Journal of Applied Hematology, 2014
Background: Stored platelet concentrates (PC) are in increasing demand for transfusion to patients with thrombocytopenia or disordered platelet function with active bleeding.
Saira Bashir, Shahida Mohsin, Huma Amin, Muhammad Rehman, Shabbir Hussain, Tahir Saeed   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source