Results 71 to 80 of about 13,707 (264)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Comparison of autologous platelet concentrates and topical steroids on oral lichen planus: a systematic review and meta-analysis

BMC Oral Health
Background Oral lichen planus is a chronic and potentially malignant disorder of oral mucosa. Corticosteroids are used as first-line therapy for oral lichen planus patients; however, they have many side effects.
Bita Azizi, Katayoun Katebi, Hosein Azizi, Maryam Hosseinpour Sarmadi   +3 more
doaj   +1 more source

Effectiveness of platelet concentrates in the treatment of temporomandibular disorders

Revista Cubana de Estomatología, 2021
Introduction: Temporomandibular disorders are a group of dysfunctions which affect the temporomandibular joint and/or associated musculoskeletal tissues.
Heber Isac Arbildo Vega, Víctor Alay Baca, Gustavo Alfredo Alberto Giribaldi Ugáz, Hernán Vásquez Rodrigo   +3 more
doaj  

Research progress of autologous platelet concentrates in the periodontal regeneration of both soft and hard tissues [PDF]

Kouqiang yixue
In recent years, the autologous platelet concentrates have increasingly been used in the field of periodontal tissue regeneration. To furnish insights that may aid in their clinical application, this article offers a comprehensive review of the evolution
PENG Wei, CHEN Xin, XIA Yiru, ZENG Wenmin, XIE Yufeng
doaj   +1 more source

Platelet factor 4 in platelet concentrates.

Journal of the Japan Society of Blood Transfusion, 1984
The release of platelet factor 4 (PF4) from platelets in platelet concentrates (PC) were investigated sequentially in the process of blood collection, and their storage at room temperature for up to 72h with agitation. No appreciable increase in PF4 release was seen immediately after blood collection.
Ishikawa, Yuko, Shimizu, Tetsuo, Hibi, Satomi, Tsurumi, Hiromi, Goto, Soji, Hasegawa, Iwazo, Fukuda, Tsuneo, Kato, Kanefusa   +7 more
openaire   +2 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Angiogenic and Regenerative Potential of Plasma-Based and Plasma-Free Platelet Concentrates Obtained via Different Fractionation and Activation Methods

Bioengineering
Background: Platelet concentrates are widely used in regenerative dentistry and maxillofacial surgery; however, the lack of protocol standardization and selection criteria results in contradictory clinical outcomes.
Irina Alekseevna Nedorubova, Viktoriia Pavlovna Basina, Anastasiia Yurevna Meglei, Maria Gennadevna Sapelnikova, Anatoly Alekseevich Kulakov, Dmitry Vadimovich Goldshtein, Tatiana Borisovna Bukharova   +6 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Factors Affecting Platelet Concentration in Platelet Concentrates from Canine Blood Donors

Journal of Veterinary Internal Medicine, 2017
Abstract Background Physiologic factors in dogs that might contribute to enhanced platelet yield in platelet concentrates (PCs) are largely unknown. Objective To determine whether individual differences in weight, age,
J.S. Raleigh, K.E. Jandrey, J. Burges, M.S. Kent   +3 more
openaire   +4 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source