Results 81 to 90 of about 28,987 (307)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Autologous Platelet Concentrates in Sports Medicine: Mechanisms of Tissue Regeneration and Clinical Applications – A Narrative Review

Quality in Sport
Background. Sports-related musculoskeletal injuries remain a major problem in both professional and recreational athletes because of their high incidence, prolonged recovery, and the limited regenerative potential of some tissues.
Karolina Niewola, Paweł Stenzel, Natalia Hariasz, Karolina Orda, Dominika Walczak, Klaudia Kasperska, Jakub Szumiło, Mariana Markiv, Michał Słowik, Kamil Arciszewski   +9 more
doaj   +1 more source

Reversal of apixaban induced alterations in hemostasis by different coagulation factor concentrates: significance of studies in vitro with circulating human blood.

PLoS ONE, 2013
Apixaban is a new oral anticoagulant with a specific inhibitory action on FXa. No information is available on the reversal of the antihemostatic action of apixaban in experimental or clinical settings.
Gines Escolar, Victor Fernandez-Gallego, Eduardo Arellano-Rodrigo, Jaume Roquer, Joan Carles Reverter, Victoria Veronica Sanz, Patricia Molina, Irene Lopez-Vilchez, Maribel Diaz-Ricart, Ana Maria Galan   +9 more
doaj   +1 more source

Crotalus atrox venom preconditioning increases plasma fibrinogen and reduces perioperative hemorrhage in a rat model of surgical brain injury. [PDF]

, 2017
Perioperative bleeding is a potentially devastating complication in neurosurgical patients, and plasma fibrinogen concentration has been identified as a potential modifiable risk factor for perioperative bleeding.
Applegate, Richard, Bull, Brian S, Gren, Eric CK, Hay, Karen L, Hayes, William K, Kelln, Wayne, Kim, Cherine H, Lekic, Tim, McBride, Devin W, Raval, Ronak, Sherchan, Prativa, Tang, Jiping, Zhang, John H   +12 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Caracterização da ativação plaquetária nos concentrados de plaquetas por citometria de fluxo

Revista Brasileira de Hematologia e Hemoterapia, 2003
Flow cytometric characterization of platelet membrane glycoproteins expression and procoagulant surface is a sensitive technique to identify platelet activation in platelet concentrates.
Landi Evaldo P., Marques Júnior José F. C.   +1 more
doaj  

Research progress of autologous platelet concentrates in the periodontal regeneration of both soft and hard tissues [PDF]

Kouqiang yixue
In recent years, the autologous platelet concentrates have increasingly been used in the field of periodontal tissue regeneration. To furnish insights that may aid in their clinical application, this article offers a comprehensive review of the evolution
PENG Wei, CHEN Xin, XIA Yiru, ZENG Wenmin, XIE Yufeng
doaj   +1 more source

The prevalence of bacterial contamination in donated blood in Dar es salaam, Tanzania [PDF]

, 2012
Blood transfusion services are required to provide blood and components which are safe in cost effective way for transfusion into patients who require the blood products.
Malimu, Emmanuel Zephania
core  

Redox Proteomics and Platelet Activation: Understanding the Redox Proteome to Improve Platelet Quality for Transfusion. [PDF]

, 2017
Blood banks use pathogen inactivation (PI) technologies to increase the safety of platelet concentrates (PCs). The characteristics of PI-treated PCs slightly differ from those of untreated PCs, but the underlying reasons are not well understood.
Abonnenc, M., Lion, N., Prudent, M., Sonego, G., Tissot, J.D.   +4 more
core   +1 more source

Comparison of Platelet Counting Technologies in Equine Platelet Concentrates [PDF]

Veterinary Surgery, 2014
Objective(1) To compare the performance of 4 platelet counting technologies in equine platelet concentrates and (2) to evaluate the ability of the Magellan platelet rich plasma (PRP) system to concentrate equine platelets.Study DesignExperimental study to assess method agreement.AnimalsAdult mixed breed horses (n = 32).MethodsAcid citrate dextrose‐A ...
Caitlin M, O'Shea, Stephen R, Werre, Linda A, Dahlgren   +2 more
openaire   +2 more sources