Results 61 to 70 of about 16,295 (299)
Cytokines in Platelet Concentrates
There are many cytokines that have been shown to increase in platelet concentrates during storage including: proinflammatory cytokines, chemokines, and transforming growth factor β. The concentrations of these cytokines can be variable depending on the method of platelet preparation, and the leukocyte and/or platelet concentration in the product.
openaire +2 more sources
Optimized Preparation Method of Platelet-Concentrated Plasma and Noncoagulating Platelet-Derived Factor Concentrates: Maximization of Platelet Concentration and Removal of Fibrinogen [PDF]
Platelet-rich plasma (PRP) has been clinically used as an easily prepared growth factor cocktail that can promote wound healing, angiogenesis, and tissue remodeling. However, the therapeutic effects of PRP are still controversial, due partly to the lack of optimized and standardized preparation protocols.
Jun, Araki +8 more
openaire +2 more sources
Metabolic parameters of the platelet concentrates.
Metabolic parameters of the platelet concentrates.
Cécile H. Kicken (820483) +4 more
core +1 more source
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
Background Platelets undergo structural, biochemical and functional alterations when stored, and platelet storage lesions reduce platelet function and half-life after transfusion.
Camila Serina Lasta +7 more
doaj +1 more source
Profiling of alterations in platelet proteins during storage of platelet concentrates
BACKGROUND: The quality of platelet concentrates (PCs) is primarily determined in vitro by selective methods (e.g., pH, aggregometry), which provide only limited information on certain platelet (PLT) characteristics.
Andreas Greinacher +21 more
core +1 more source
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi +9 more
wiley +1 more source
ABSTRACT Background Chronic limb‐threatening ischemia (CLTI) is a severe form of lower‐extremity artery disease characterized by distal lesions and microcirculatory impairment, limiting revascularization efficacy. Rheocarna is a direct hemoperfusion low‐density lipoprotein (LDL) adsorption device with potential rheological and anti‐inflammatory ...
Kunihiro Ishioka +12 more
wiley +1 more source
BACKGROUND: The relevance of some plasma-based medicinal products, especially platelet concentrates in modern medical care, is confirmed by their inclusion in the World Health Organization Essential Medicines.
Tesleemah Oluwakemi Davies-Folorunso +9 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source

