Green fluorescent protein (GFP) color reporter gene visualizes parvovirus B19 non-structural segment 1 (NS1) transfected endothelial modification. [PDF]
BACKGROUND: Human Parvovirus B19 (PVB19) has been associated with myocarditis putative due to endothelial infection. Whether PVB19 infects endothelial cells and causes a modification of endothelial function and inflammation and, thus, disturbance of ...
Thomas Wurster +10 more
doaj +3 more sources
Platelet endothelial cell adhesion molecule-1 mediates endothelial-cardiomyocyte communication and regulates cardiac function. [PDF]
Background Dilated cardiomyopathy is characterized by impaired contractility of cardiomyocytes, ventricular chamber dilatation, and systolic dysfunction. Although mutations in genes expressed in the cardiomyocyte are the best described causes of reduced contractility, the importance of endothelial‐cardiomyocyte ...
McCormick ME +7 more
europepmc +4 more sources
Platelet Endothelial Cell Adhesion Molecule-1 Polymorphism in Patients with Bronchial Asthma
Asthma is considered as a chronic inflammatory airway disease and defined as increased tracheobronchial responsiveness to variety of stimuli. Edema and inflammatory cell infiltration in airway is observed in the asthmatic patients.
Ebrahim Nadi +3 more
doaj +2 more sources
Background Platelet–endothelial interactions are thought to contribute to early atherogenesis. These interactions are potentiated by oxidative stress. We used in vivo molecular imaging to test the hypothesis that platelet–endothelial interactions occur ...
Eran Brown +14 more
doaj +1 more source
Platelet adhesion in atherogenesis [PDF]
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Master of PhilosophyPlatelets are known to play a key role in acute coronary events, such as myocardial infarction, associated with advanced
Watkins, Jennifer
core +3 more sources
Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes. [PDF]
The lack of suitable animal models for the study of cytoadhesion of P. falciparum-infected erythrocytes (IEs) has necessitated in vitro studies employing a range of cell lines of either human tumour origin (e.g., BeWo and C32 cells) or non-human origin ...
Gertrude Ecklu-Mensah +6 more
doaj +1 more source
BackgroundKawasaki disease (KD) is an acute vasculitis that may result in permanent coronary artery damage with unknown etiology. Endothelial cell (EC) dysfunction and platelet hyperactivity are the hallmarks of KD.
Manli Guo +8 more
doaj +1 more source
Endotheliopathy and Platelet Dysfunction as Hallmarks of Fatal Lassa Fever
Lassa fever (LF) causes multisystem disease and has a fatality rate
Lucy E. Horton +12 more
doaj +1 more source
Persistent inflammation and endothelial activation in HIV-1 infected patients after 12 years of antiretroviral therapy. [PDF]
The study investigated markers of inflammation and endothelial activation in HIV infected patients after 12 years of successful combination antiretroviral treatment (cART).Inflammation and endothelial activation were assessed by measuring levels of ...
Frederikke F Rönsholt +4 more
doaj +1 more source
The platelet endothelial cell adhesion molecule‐1 (PECAM1) contributes to endothelial barrier function [PDF]
In this study we have analyzed the role of the platelet‐endothelial cell adhesion molecule‐1 (PECAM1) in vascular barrier function. PECAM1 is an immunoglobulin gene superfamily member expressed by endothelial cells at the cell boundaries. Macromolecule permeability assays performed on cell monolayers that express native or transfected PECAM1, indicated
Ferrero, Elisabetta +3 more
openaire +2 more sources

