Angiogenesis in Platelet Endothelial Cell Adhesion Molecule-1-Null Mice [PDF]
The American Journal of Pathology, 2009 Platelet endothelial cell adhesion molecule (PECAM)-1 has been previously implicated in endothelial cell migration; additionally, anti-PECAM-1 antibodies have been shown to inhibit in vivo angiogenesis. Studies were therefore performed with PECAM-1-null mice to further define the involvement of PECAM-1 in blood vessel formation.
Gaoyuan, Cao +5 more
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Arsenic Exposure Increases Monocyte Adhesion to the Vascular Endothelium, a Pro-Atherogenic Mechanism. [PDF]
PLoS ONE, 2015 Epidemiological studies have shown that arsenic exposure increases atherosclerosis, but the mechanisms underlying this relationship are unknown. Monocytes, macrophages and platelets play an important role in the initiation of atherosclerosis. Circulating
Maryse Lemaire +8 more
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THE MOLECULAR ORGANIZATION OF ENDOTHELIAL JUNCTIONS IN VASCULAR PERMEABILITY [PDF]
Euromediterranean Biomedical Journal, 2021 Vascular permeability is an innate function of the circulatory system that regulates the flux of fluid, proteins, and immune cells from blood to tissue.
Angela Bruna Maffione
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Platelet endothelial cell adhesion molecule-1 signaling inhibits the activation of human platelets [PDF]
Blood, 2002 Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) is a 130-kd transmembrane glycoprotein and a member of the growing family of receptors with immunoreceptor tyrosine-based inhibitory motifs (ITIMs). PECAM-1 is expressed on platelets, certain T cells, monocytes, neutrophils, and vascular endothelial cells and is involved in a range of ...
Cicmil, Milenko +4 more
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Platelet PI3Kγ Contributes to Carotid Intima-Media Thickening under Severely Reduced Flow Conditions. [PDF]
PLoS ONE, 2015 Studies have begun to focus on the emerging function of platelets as immune and inflammatory cells that initiate and accelerate vascular inflammation.
Cuiping Wang +4 more
doaj +1 more source
Materials Today Bio, 2022 The endothelium plays an important regulatory role for cardiovascular homeostasis. Rapid endothelialization of small diameter vascular grafts (SDVGs) is crucial to ensure long-term patency.
Sabrina Rohringer +9 more
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Increased levels of soluble forms of E-selectin and ICAM-1 adhesion molecules during human leptospirosis. [PDF]
PLoS ONE, 2017 Leptospirosis is a multisystemic zoonotic disease with infiltration of visceral organs by Leptospira. The capacity of the vascular endothelium to grant immune cell recruitment and activation in target organs during the disease course remains poorly ...
Loic Raffray +5 more
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Soluble adhesion molecules and angiotensin-converting enzyme in dementia
Neurobiology of Disease, 2007 We aimed to determine plasma and cerebrospinal fluid (CSF) levels of angiotensin-converting enzyme (ACE) and the soluble forms of intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1) and platelet endothelial cell ...
Henrietta M. Nielsen +3 more
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Regulation of platelet biology by platelet endothelial cell adhesion molecule-1
Platelets, 2011 Platelet endothelial cell adhesion molecule-1 (PECAM-1), an immunoreceptor tyrosine-based inhibitory motif containing receptor, plays diverse and apparently contradictory roles in regulating the response of platelets to stimuli; inhibiting platelet response to immunoreceptor tyrosine-based activation motif and G protein-coupled receptor signalling ...
Chris I, Jones +2 more
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Platelet Endothelial Cell Adhesion Molecule‐1 is Expressed in Adenoidal Crypt Epithelial Cells [PDF]
Scandinavian Journal of Immunology, 2005 AbstractThe adenoidal epithelial crypt is a potential site of antigen transport from pharyngeal lumen to adenoidal tissue. The base of the crypt is consistently infiltrated with leucocytes, forming a reticular lymphoepithelial structure. To evaluate mechanisms that possibly mediate leucocyte infiltration, expressions of leucocyte adhesion molecules ...
M, Pajusto, J, Tarkkanen, P S, Mattila
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