Results 241 to 250 of about 34,180,212 (292)

Immunopathogenesis of Sickle Cell Disease: Mechanisms of Immune Dysregulation and Clinical Consequences, a Narrative Review. [PDF]

J Blood Med
Egba SI, Umeh VA, Alaebo PO, Chukwuma UV.   +3 more
europepmc   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

NNMT-associated metabolic-thromboinflammatory-immune co-activation in heterogeneous CTC clusters: a hypothesis-generating computational framework". [PDF]

BMC Cancer
Gong J, Wang Z, Shi Y, Ren M, Li T, Li G, Peng R.   +6 more
europepmc   +1 more source

Xenotransplantation of the Porcine Lung-From Immunological Barriers to Emerging Experimental Strategies. [PDF]

Xenotransplantation
Roters N, Varma N, Ramm R, Niemann H, Zardo P, Ruhparwar A, Goecke T.   +6 more
europepmc   +1 more source

Deubiquitinases as Regulators and Therapeutic Targets in Vascular Diseases. [PDF]

Int J Mol Sci
Lin ZK, Wang L.
europepmc   +1 more source

Platelets in systemic lupus erythematosus: from hemostatic allies to pathogenic drivers. [PDF]

Front Immunol
Wu Y, Yang Z, Huang S, Bao J, Fan Y, Xie G.   +5 more
europepmc   +1 more source

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Platelet endothelial cell adhesion molecule-1 is a gatekeeper of neutrophil transendothelial migration in ischemic stroke

Brain, Behavior, and Immunity, 2021
Adhesion molecules are key elements in stroke-induced brain injury by regulating the migration of effector immune cells from the circulation to the lesion site. Platelet endothelial cell adhesion molecule-1 (PECAM-1) is an adhesion molecule highly expressed on endothelial cells and leukocytes, which controls the final steps of trans-endothelial ...
Tim Magnus, Jens Fiehler, Peter Ludewig
exaly   +4 more sources