Results 71 to 80 of about 34,180,212 (292)
PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing
Advanced Healthcare Materials, EarlyView.Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu +10 morewiley +1 more sourceHarnessing Physiological Shear Stress in a Perfusion Bioreactor for Enhanced Endothelialization of Small‐Diameter Vascular Grafts
Advanced NanoBiomed ResearchThis study presents a versatile perfusion bioreactor system designed to evaluate endothelialization on electrospun polycaprolactone (PCL)–gelatin vascular grafts under controlled flow conditions that mimic physiological and pathological shear stress. The Praveesuda L. Michael, Yuen Ting Lam, Timothy C. Mitchell, Miguel Santos, Alex H. P. Chan, Xinying Liu, Angus J. Grant, Matthew J. Moore, David F. Fletcher, Richard P. Tan, Steven G. Wise +10 moredoaj +1 more sourceCardiovascular molecular imaging [PDF]
, 2013 Although there have been significant improvements in the treatment of cardiovascular diseases they still remain the main cause of morbidity and mortality globally. Currently available diagnostic approaches may not be adequate to detect pathologic changes Khanicheh, Elhamcore +1 more sourceAn Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke
Advanced Healthcare Materials, EarlyView.Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li +9 morewiley +1 more sourceSerum levels of soluble platelet endothelial cell adhesion molecule-1 and vascular cell adhesion molecule-1 are decreased in subjects with autism spectrum disorder [PDF]
Molecular Autism, 2013 AbstractBackgroundAdhesion molecules, such as platelet-endothelial adhesion molecule-1 (PECAM-1), platelet selectin (P-selectin), endothelial selectin (E-selectin), intracellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1), are localized on the membranes of activated platelets and leukocytes and on the vascular ...Kameno, Yosuke, Iwata, Keiko, Matsuzaki, Hideo, Miyachi, Taishi, Tsuchiya, Kenji J, Matsumoto, Kaori, Iwata, Yasuhide, Suzuki, Katsuaki, Nakamura, Kazuhiko, Maekawa, Masato, Tsujii, Masatsugu, Sugiyama, Toshirou, Mori, Norio +12 moreopenaire +2 more sourcesThe anti-inflammatory agent bindarit inhibits neointima formation in both rats and hyperlipidaemic mice [PDF]
, 2008 Aims Bindarit is an original compound with peculiar anti-inflammatory activity due to a selective inhibition
of a subfamily of inflammatory chemokines, including the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8. In this study, we Vandekerckhove, Leni, Sepulveda, E., Szweda, Luke I., Del Campo, Andrea, Xuemei Wang, McBride, Fiona, Sergio Lavandero, Vandekerckhove, L., Smirnov, Sergey V., LeRoith, Derek, Guglielmotti, A., KRIEGER, Jose Eduardo, Waki, H., Oliveira-Sales, Elizabeth B, Llanos, Anibal J., Pavan K. Battiprolu, Evan Dale Abel, Xu, H, De Keulenaer, Gilles, Ng, Chee Peng, Schafer, S., Hewinson, James, Herman H.W. Silljé, Llanos, A. J., Yuki Kawashima, Lincz, L., Parer, Julian T., Giussani, Dino A., Waki, Hidefumi, Nemchenko, Andriy, CARRILLO-SEPULVEDA, Maria Alicia, Quiroga, Clara, Hendy, EB, De Meester, I., 许秀琴, Willem P.T. Ruifrok, Lisa Chilton, Poon, K.L., Toward, Marie, Ebensperger Darrouy, Germán, Smirnov, Sergey V, Ghofrani, H., Tan, Kar Tong, Tang, C., Cannon, Megan V., Mueller, O., Vicencio, José Miguel, Andrea del Campo, Ruifrok, Willem P. T., Wirth, A., Biondi, G., Brum, Patricia C., Casanello, P., Paula Clancy, Korzh, Vladimir, Sepúlveda Kattan, Esteban, Matheeussen, V., Loutzenhiser , Kathy, DAVEL, Ana P., Lustig, K., Sanhueza, E. M., GEDICKE, Christina, CARDOSO, Leandro, Kramer, Frank, BARRETO-CHAVES, Maria Luiza M., Wiek H. van Gilst, Toward, M, Poon, Kar Lai, Hanson, Mark A., Demolder, Marc, Liu, B, Ebensperger, R., Reyes, V. R., Derek LeRoith, Giannotta, M., WITT, Christian C., Golledge, J, LABEIT, Siegfried, Pablo Aranguiz, Hervent, A.S., Westenbrink, B. Daan; id_orcid, Shoshana Yakar, GRASSIA, GIANLUCA, Baerts, Lesley, Wei, Yang Ye, Casanello, Paola, Mochly-Rosen, Daria, Pullamsetti, S., Blanco, C. E., BRITTO, Luiz R. G., De Meester, Ingrid, ROSSONI, Luciana V., Llanos Mansilla, Jorge, Kasparov, S., Ascione, R., McBride, F., Toro, Barbra, Megan V. Cannon, Herrera, Emilio A., Baerts, L., Riquelme, Raquel A., Maguire, J., Takefuji, M., Clancy, P., Riquelme González, Raquel, Boehm, M., Dominiczak, A.F., KRAEMER, Elisabeth, Fernández, Carolina, Gatica, Damián, Herrera, E. A., Xu, Xiu Qin, Paulus, Walter J., Joseph A. Hill, Althoff, T., Toward, M., de Boer, Rudolf A., Koblar, S., Milting, H., Krämer, Elisabeth, BORIN, Thaiz Ferraz, Linke, Wolfgang A., Ellinghaus, P., Lisa Lincz, Yakar, Shoshana, Offermanns, S., Loutzenhiser, Rodger, Andriy Nemchenko, Battiprolu, Pavan K., Chiong Lay, Mario, B. Daan Westenbrink, Barbra Toro, BARAUNA, Valerio Garrone, Pulgar, Victor M., Hendy, E.B., Troncoso, Rodrigo, Kawashima, Yuki, KIHARA, Alexandre H., Popp, R., Lavandero, Sergio, LECKER, Stewart H., Wang, Xuemei, Liu, Beihui, Paulus, W.J., Colman, A., Dominiczak, Anna F, Giannotta, M, Paton, Julian, De Keulenaer, G.W., Ialenti, A., Oliveira-Sales, E.B., Lincz, Lisa, SCHLOSSAREK, Saskia, Dominiczak, Anna F., Katus, H., Kasparov, S, Cabello, Gertrudis, CAO, Peirang, Guglielmotti A., Ascione, R, Casnello, Paola, ESCHENHAGEN, Thomas, Sanhueza, Emilia M., MIYAKAWA, Ayumi Aurea, Clancy, Paula, Lavandero González, Sergio, Golledge, Jonathan, Chilton, Lisa, Sanhueza Reinoso, Emilia, Herrera Videla, Emilio, Graham, D, FORTES, Zuleica Bruno, Seeger, W., Liu, B., Pedrozo Cibils, Zully, Giussani, D. A., Hewinson, J, Ebensperger, G., Lincz, L, Oliveira-Sales, EB, Rodríguez, E., Korzh, V., YING, Zhekang, Donoso Laurent, Paulina, Campo, Andrea del, Hanson, M. A., Rudolf A. de Boer, CARRIER, Lucie, Graham, Delyth, Blanco, Carlos E., Golledge, J., CERAVOLO, Graziela S., Koblar, S, CARVALHO, Maria Helena, ROCHA, Matheus L., Paton, Julian F R, Simon Koblar, Sepulveda-Kattan, Esteban, Gillette, Thomas G., Pulgar, V. M., Ascione, Raimondo, Ferreira, Julio C., Parra, Valentina, Schermuly, R., Paton, Julian Francis Richmond, Biondi G., Matheeussen, Veerle, Parer, J. T., McBryde, Fiona, Waki, H, Grassia, G., Xu, H., Colman, Alan, Hamdani, Nazha, Mendez, Natalia, Mangano G., Mahmud, Hasan, Hendy, Emma B., Fisslthaler, B., Demolder, M., TOSTES, Rita C., Wang, S., Maddaluno, M., Ebensperger, Renato, Kathy Loutzenhiser, Oliveira-Sales, Elizabeth Barbosa de [UNIFESP], WEBB, R. Clinton, Dominiczak, AF, MEARINI, Giulia, Aranguiz, Pablo, Paton, J.F.R., MAFFIA, PASQUALE, Kojonazarov, B., Giannotta, Monica, Kasparov, Sergey, BENDHACK, Lusiane M., Inge Vreeswijk-Baudoin, Vreeswijk-Baudoin, Inge, WILLIS, Monte S., Xu, X.Q., MADDALUNO, MARCELLA, Hewinson, J., Hamdani, N., Jose Miguel Vicencio, Hervent, Anne-Sophie, Sillje, Herman H. W., Kast, R., Wei, Y.Y., Hendy, Emma B, Abel, Evan Dale, van Gilst, Wiek H., Shi, L., Koblar, Simon, GOMES, Marcelo D., Linke, W.A., Goedecke, A., Riquelme, R. A., Jonathan Golledge, DALLAN, Luis Alberto de Oliveira, Elgheznawy, A., Rodger Loutzenhiser, Mario Chiong, Westenbrink, B. Daan, Klein, M., Graham, D., Rodrigo Troncoso, Schweda, F., Chiong, Mario, Loutzenhiser, Kathy, Tan, K.T., Thomas G. Gillette, Ng, C.P., Hill, Joseph A., Ebensperger, German, Valentina Parra, LAURINDO, Francisco R., Maguire, Jane, Rodríguez, Andrea E., Fleming, I., Reyes, Roberto V., Janssen, W., Xu, Haibo, CAMPOS, Luciene Cristina Gastalho, GIACHINI, Fernanda R. C., Maffia, P., Mangano, G., Jungmann, A., IALENTI, ARMANDO, Churchill, Eric N., Hasan Mahmud, Wettschureck, N., Mendez, N., Sánchez, Gina, Dahal, B., WEBB, Robert Clinton, Maguire, J, Torrealba, Natalia, Clancy, P, Jane Maguire, Kramer, F., Sergey V. Smirnov +300 morecore +3 more sourcesMicrofluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications
Advanced Healthcare Materials, EarlyView.Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare +6 morewiley +1 more sourceCleavage of platelet endothelial cell adhesion molecule‐1 (PECAM‐1) in platelets exposed to high shear stress [PDF]
Journal of Thrombosis and Haemostasis, 2004 Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a 130 kDa transmembrane glycoprotein that belongs to the immunoglobulin superfamily and is expressed on the surface of endothelial cells, platelets, and other blood cells. Although the importance of this adhesion molecule in various cell-cell interactions is established, its functional ...Y, Naganuma, K, Satoh, Q, Yi, N, Asazuma, Y, Yatomi, Y, Ozaki +5 moreopenaire +2 more sources
