Healthy pediatric platelets are moderately hyporeactive in comparison with adults’ platelets
Studies on platelet function in children older than neonatal period are few and their results are controversial. The pediatric platelets were alternatively reported to be more active or less active than adults’ ones.
Evgeniya A. Ponomarenko+9 more
doaj +1 more source
Anomalous Platelet Transport & Fat-Tailed Distributions [PDF]
The transport of platelets in blood is commonly assumed to obey an advection-diffusion equation. Here we propose a disruptive view, by showing that the random part of their velocity is governed by a fat-tailed probability distribution, usually referred to as a L\'evy flight.
arxiv
Depletion potential in colloidal mixtures of hard spheres and platelets [PDF]
The depletion potential between two hard spheres in a solvent of thin hard disclike platelets is investigated by using either the Derjaguin approximation or density functional theory. Particular attention is paid to the density dependence of the depletion potential.
arxiv +1 more source
Function and Platelet Count in Thrombocyte Concentrate (TC) During the Storage [PDF]
Background: Evaluation for platelet transfusion is not optimal for this moment even in upstream at theblood center or in downstream at the hospital. The purpose of this study was to determine the effect ofstorage time to changes in pH, platelet count and
Marpaung, E. (Elida)+3 more
core
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha+6 more
wiley +1 more source
Heparin and protamine are fundamental in the management of anticoagulation during cardiac surgery. Excess protamine has been associated with increased bleeding.
Mattias Törnudd+5 more
doaj +1 more source
Effect of Qingkailing injection on platelets function preserved in vitro
Objective To investigate the effect of Qingkailing injection on platelet function preserved in vitro. Methods A total of 15 bags of plateletpheresis (≥250 mL/bag), adding Qingkailing injection(1.25 mL/bag) at the final concentration of 1%, were stored at
Jie LI+7 more
doaj +1 more source
Bulk and wetting phenomena in a colloidal mixture of hard spheres and platelets [PDF]
Density functional theory is used to study binary colloidal fluids consisting of hard spheres and thin platelets in their bulk and near a planar hard wall. This system exhibits liquid-liquid coexistence of a phase that is rich in spheres (poor in platelets) and a phase that is poor in spheres (rich in platelets). For the mixture near a planar hard wall,
arxiv +1 more source
The effects of signal transducer and activator of transcription three mutations on human platelets [PDF]
Involvement of signal transducer and activator of transcription 3 (STAT3) in inflammation is well known. Recently, a role for STAT3 in platelet activation and platelet production has been suggested.
Aleva, Floor E.+9 more
core +3 more sources
Loss of mDia1 and Fhod1 impacts platelet formation but not platelet function [PDF]
An organized and dynamic cytoskeleton is required for platelet formation and function. Formins are a large family of actin regulatory proteins which are also able to regulate microtubule dynamics.
Bacon, Andrea+8 more
core +1 more source