Utility of the Platelet Function Analyzer in Patients with Suspected Platelet Function Disorders: Diagnostic Accuracy Study [PDF]
TH Open, 2020 Introduction The platelet function analyzer (PFA) is widely used as a screening tool for bleeding disorders in various settings. The diagnostic performance regarding platelet function disorders (PFDs), which are among the most common inherited bleeding ...
Jonas Kaufmann +3 more
doaj +7 more sources
Platelet Dysfunction in Blood Donors Detected by Platelet Function Analyzer PFA-100™. [PDF]
Cureus, 2022 Background Platelet transfusions may be indicated to prevent and treat bleeding in patients with quantitative or qualitative platelet defects. Millions of platelet components are transfused worldwide. It is well known that platelet dysfunction predicts blood loss after surgery.
Belkacemi M, Berber A.
europepmc +3 more sources
Investigation of Platelet Function Analyzer 200 platelet function measurements in healthy cats and cats receiving clopidogrel. [PDF]
J Vet Diagn Invest, 2023 The Platelet Function Analyzer 200 (PFA-200; Siemens) is an in vitro substitute for in vivo bleeding time that is designed to investigate platelet function in a more physiologic manner than traditional aggregometry. The analyzer reports a closure time (CT) as a marker of platelet function, and may also report the calculated platelet function ...
Kornya MR +3 more
europepmc +3 more sources
Screening for platelet function disorders with Multiplate and platelet function analyzer [PDF]
Platelets, 2019 Light transmission aggregation (LTA) is the gold standard for the diagnosis of platelet function disorders (PFDs), but it is time-consuming and limited to specialized laboratories.
Floor C. J. I. Moenen +10 more
doaj +3 more sources
The role of platelet function analyzer-200 in predicting perioperative bleeding risk [PDF]
The Korean Journal of Internal Medicine, 2020 Background/Aims Various preoperative screening tests, such as platelet count, prothrombin time, activated partial thromboplastin time, and bleeding time, have been widely used to evaluate the risk of bleeding during surgery.
Eun Sang Yu +10 more
doaj +2 more sources
Establishment of reference intervals for Platelet Function Analyzer -100 closure time in Algerian adults. [PDF]
PLoS ONE, 2021 IntroductionThe Platelet Function Analyzer-100 (PFA-100) is a point of care instrument that simulates plug formation under high shear flow. The PFA-100 measures the time required to occlude the aperture in a biochemically active cartridge and is ...
Malika Belkacemi +2 more
doaj +2 more sources
Effectiveness of Platelet Function Analyzer-100 for Laboratory Detection of Anti-Platelet Drug-Induced Platelet Dysfunction. [PDF]
Ann Lab Med, 2019 High on-treatment platelet reactivity (HTPR) is the phenomenon wherein patients exhibit normal platelet activity in laboratory testing despite adequate adherence to anti-platelet treatment. We investigated the detection rates of Platelet Function Analyzer (PFA)-100 (Dade Behring AG, Düdingen, Switzerland) for drug-induced platelet dysfunction and ...
Kweon OJ, Lim YK, Kim B, Lee MK, Kim HR.
europepmc +3 more sources
Platelet function testing in pigs using the Multiplate® Analyzer.
PLoS ONE, 2019 For endovascular research pigs are an established animal model. However, experiences regarding analyses of platelet inhibition in pigs using the Multiplate® Analyzer are limited.
Sarah Heringer +6 more
doaj +5 more sources
Evaluation of clopidogrel responsiveness using the Platelet Function Analyzer-200 (PFA-200) in dogs [PDF]
Frontiers in Veterinary ScienceWe aimed to evaluate the prevalence of clopidogrel resistance in hypercoagulable dogs using the Platelet Function Analyzer-200 (PFA-200) P2Y cartridge; further, we aimed to assess the utility of hematocrit (HCT), platelet count (PLT), prothrombin time ...
Joon-Ho Shin +2 more
doaj +2 more sources
The Role of Platelet Function Analyzer Testing in Cardiac Surgery Transfusion Management. [PDF]
Transfus Med Hemother, 2017 <b>Background: </b>Identifying high-risk patients for transfusion after cardiac operations would alter postoperative management. The aim of this study was to investigate closure time (CT) measured by platelet function analyzer (PFA) for prediction of bleeding and transfusions.
Bogdanic D +7 more
europepmc +5 more sources