Results 211 to 220 of about 32,674 (247)

Microfluidic platelet function analyzer for shear-induced platelet activation studies

2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.02EX578), 2003
Platelet function is suggestive of pathological conditions in heart related diseases. With current insufficient prognostic devices, we see the need for a device to assess complete platelet function. This work presents our preliminary microfluidic device for the analysis of shear-induced platelet activation, which is crucial in studying the pathological
A.S. Kantak, B.K. Gale, Y. Lvov, S.A. Jones   +3 more
openaire   +1 more source

Monitoring aspirin therapy with the Platelet Function Analyzer‐100

Scandinavian Journal of Clinical and Laboratory Investigation, 2008
Low platelet response to aspirin has been reported to be associated with a high incidence of vascular events. The reported prevalence of aspirin low-responsiveness varies, which may be explained by poor reproducibility of the methods used to evaluate aspirin response and low compliance.
Mortensen, Jette, Poulsen, Tina Svenstrup, Grove, Erik, Refsgaard, Jens, Nielsen, Helle Ladefoged, Pedersen, Susanne, Hedegaard, Sofie, Hvas, Anne-Mette, Kristensen, Steen Dalby   +8 more
openaire   +3 more sources

Platelet Function Analyzed by Light Transmission Aggregometry

2017
Analysis of platelet function is widely used for diagnostic work-up in patients with increased bleeding tendency. During the last decades, platelet function testing has also been introduced for evaluation of antiplatelet therapy, but this is still recommended for research purposes only.
Hvas, Anne-Mette, Favaloro, Emmanuel J
openaire   +3 more sources

Evaluation of platelet count and platelet function analyzer – 100 testing for prediction of platelet transfusion following coronary bypass surgery

Scandinavian Journal of Clinical and Laboratory Investigation, 2020
Platelet transfusions are commonly administered to treat bleeding in cardiac surgery. The aim of this study was to compare platelet (PLT) count and values of collagen adenosine diphosphate closure time (cADP-CT) measured by Platelet Function Analyzer (PFA) for prediction of PLT transfusion therapy following coronary bypass surgery. For this prospective
Bogdanić, Dejana, Bogdanić, Nikolina, Karanović, Nenad   +2 more
openaire   +3 more sources

Activated platelets and impaired platelet function in intensive care patients analyzed by flow cytometry

Blood Coagulation & Fibrinolysis, 1996
Intensive care patients often have disturbances in their coagulation and fibrinolysis systems, which may result in haemorrhage or disseminated intravascular coagulation (DIC). DIC is a dreaded complication that may develop rapidly and has a high mortality rate.
T H, Lundahl, T L, Lindahl, I H, Fagerberg, N, Egberg, A, Bunescu, A, Larsson   +5 more
openaire   +2 more sources

Using the Platelet Function Analyzer-100 for monitoring aspirin therapy

Thrombosis Research, 2007
The aim of the study was to evaluate the test characteristics of the Platelet Function Analyzer-100 (PFA-100) in patients treated with aspirin.The study consisted of two sub-studies. In study 1, 10 patients with ischemic heart disease (IHD) and 10 controls had platelet function assessed by optical platelet aggregation and the PFA-100 method in two 5 ...
Poulsen, Tina Svenstrup, Mickley, Hans, Korsholm, Lars, Licht, Peter Bjørn, Haghfelt, Torben, Jørgensen, Bo   +5 more
openaire   +3 more sources

Formation of mixed platelet-PMN leukocyte aggregates in the platelet function analyzer (PFA-100) device

Thrombosis and Haemostasis, 2007
Formation of mixed platelet-PMN leukocyte aggregates in the platelet function analyzer (PFA-100) device -
Norma, Maugeri, Maria Benedetta, Donati, Giovanni, de Gaetano, Chiara, Cerletti   +3 more
openaire   +2 more sources

Impact – The Cone and Plate(let) Analyzer: Testing Platelet Function and Anti-Platelet Drug Response

Pathophysiology of Haemostasis and Thrombosis, 2006
The Impact [cone and plate(let) analyzer (CPA) Technology]is testing whole blood platelet adhesion and aggregation under arterial flow conditions. The adhered platelets are stained and the percentage of surface covered (SC) by the stained objects and the average size (AS) of the objects are determined by image analyzer.
Naphtali, Savion, David, Varon
openaire   +2 more sources

Determination of platelet aggregation inhibition during percutaneous coronary intervention with the platelet function analyzer PFA-100

American Heart Journal, 2002
A simple device to rapidly evaluate platelet function may aid in optimizing glycoprotein IIb/IIIa inhibition during percutaneous coronary intervention (PCI). We prospectively studied platelet function in 250 patients receiving abciximab or eptifibatide during PCI.The platelet function analyzer PFA-100 (Dade-Behring, Deerfield, Ill) measures platelet ...
Mina, Madan, Scott D, Berkowitz, Douglas J, Christie, Astrid C, Smit, Kristina N, Sigmon, James E, Tcheng   +5 more
openaire   +2 more sources

Monitoring Acetylsalicylic Acid Effects with the Platelet Function Analyzer PFA-100

Seminars in Thrombosis and Hemostasis, 2005
The efficacy of acetylsalicylic acid (ASA) to prevent thrombotic or embolic events in patients with atherosclerosis was demonstrated in many large trials. Despite this fact, a subpopulation of patients experiences acute myocardial infarction or cerebrovascular ischemia indicating a nonresponsiveness to ASA.
Martin, Feuring, Armin, Schultz, Ralf, Losel, Martin, Wehling   +3 more
openaire   +2 more sources