Results 21 to 30 of about 32,674 (247)

Ticagrelor Is Superior to Clopidogrel in Inhibiting Platelet Reactivity in Patients With Minor Stroke or TIA

Frontiers in Neurology, 2020
Background: The combination of clopidogrel and aspirin is recommended for the treatment of patients with acute minor stroke or transient ischemic attack (TIA).
Yingying Yang, Yingying Yang, Weiqi Chen, Weiqi Chen, Yuesong Pan, Yuesong Pan, Hongyi Yan, Hongyi Yan, Xia Meng, Xia Meng, Liping Liu, Liping Liu, Yongjun Wang, Yongjun Wang, Yilong Wang, Yilong Wang   +15 more
doaj   +1 more source

Platelet Dysfunction in Primary Thrombocythemia Using the Platelet Function Analyzer, PFA-100 [PDF]

American Journal of Clinical Pathology, 2005
We measured platelet function by standard aggregometric tests and by the PFA-100 (Dade Behring, Newark, DE) in samples from 55 patients with primary thrombocythemia (PT) and 26 healthy volunteers. Platelet function was evaluated in platelet-rich plasma by aggregation tests.
Jesús M, Cesar, Dunia, de Miguel, Angel, García Avello, Carmen, Burgaleta   +3 more
openaire   +2 more sources

Validation of Plateletworks ADP for the ProCyte Dx analyzer

Journal of Veterinary Internal Medicine, 2023
Background Platelet function testing in cats allows determination of clopidogrel effect. Plateletworks assesses aggregation based on decreasing platelet counts on hematology analyzers in response to agonists.
Matthew R. Kornya, Anthony C. G. Abrams‐Ogg, Shauna L. Blois, R. Darren Wood   +3 more
doaj   +1 more source

Dose-dependent effect of canine lyophilized platelet on an in vitro hemodilution model

BMC Veterinary Research, 2023
The transfusion of stored platelets has emerged as an efficient method for treating dogs with thrombocytopenia. However, the availability of fresh platelets is limited in veterinary medicine due to demanding storage conditions. Lyophilized platelets have
Mu-Young Kim, Hyun-Jung Han
doaj   +1 more source

Comprehensive Approach to Developing Baseline Reference Ranges for Platelet Function

Педиатрическая фармакология, 2023
Background. Thrombocytopathies are topical issues of pediatrics. Platelet dysfunction clinically manifests as thrombotic and hemorrhagic events of various severity and location. Platelet function can be evaluated via aggregatometry.
Olga B. Gordeeva, Maria S. Karaseva, Vasily A. Lastovka, Nato D. Vashakmadze, Margarita A. Soloshenko, Gregory V. Revunenkov, Kirill A. Valyalov, Viktor V. Altunin   +7 more
doaj   +1 more source

Long-term treated HIV infection is associated with platelet mitochondrial dysfunction

Scientific Reports, 2021
HIV infection and antiretroviral therapy have been linked to mitochondrial dysfunction. The role of platelet mitochondrial dysfunction in thrombosis, immunoregulation and age-related diseases is increasingly appreciated.
Wouter A. van der Heijden, Lisa van de Wijer, Martin Jaeger, Karin Grintjes, Mihai G. Netea, Rolf T. Urbanus, Reinout van Crevel, Lambertus P. van den Heuvel, Maaike Brink, Richard J. Rodenburg, Philip G. de Groot, Andre J. van der Ven, Quirijn de Mast   +12 more
doaj   +1 more source

Platelet abnormalities in patients with Parkinson's disease undergoing preoperative evaluation for deep brain stimulation

Scientific Reports, 2022
Normal hemostatic function is important for reduction of the risk of intracranial hemorrhage during stereotactic neurosurgery including deep brain stimulation (DBS) surgery.
Sheng-Che Chou, Chun-Hwei Tai, Sheng-Hong Tseng   +2 more
doaj   +1 more source

The Antiplatelet Action of S-Nitroso Human Serum Albumin in Whole Blood

Biomedicines, 2022
Nitric oxide donors (NO-donors) have been shown to have therapeutic potential (e.g., ischemia/reperfusion injury). However, due to their release rate/antiplatelet properties, they may cause bleeding in patients.
Melina Tsiountsioura, Gerhard Cvirn, Axel Schlagenhauf, Harald Haidl, Kathrin Zischmeier, Nicole Janschitz, Martin Koestenberger, Willibald Wonisch, Margret Paar, Thomas Wagner, Eva-Christine Weiss, Seth Hallström   +11 more
doaj   +1 more source

Evaluation of platelet function in dogs with cardiac disease using the PFA‐100 platelet function analyzer [PDF]

Veterinary Clinical Pathology, 2009
Background:Cardiac disease has the potential to alter platelet function in dogs. Evaluation of platelet function using the PFA‐100 analyzer in dogs of multiple breeds and with a broad range of cardiac conditions would help clarify the effect of cardiac disease on platelets.Objectives:The objective of this study was to assess differences in closure time
Noel, Clancey, Shelley, Burton, Barbara, Horney, Allan, Mackenzie, Andrea, Nicastro, Etienne, Côté   +5 more
openaire   +2 more sources

The bleeding diathesis in patients with hereditary haemorrhagic telangiectasia is not due to impaired platelet function

Orphanet Journal of Rare Diseases, 2023
Background Patients with the rare disease; Hereditary haemorrhagic telangiectasia (HHT) often bleed from telangiectatic lesions in mucosal surfaces. Studies suggest that impaired platelet function may also play a role in their bleeding tendency.
Anne Lørup Lyster, Signe Hedengran Biørn, Anette Drøhse Kjeldsen, Christian Nielsen, Bibi Lange, Annette Dam Fialla, Pernille Just Vinholt   +6 more
doaj   +1 more source