Results 101 to 110 of about 7,899,636 (253)

Laboratory testing for platelet function disorders [PDF]

International Journal of Laboratory Hematology, 2015
SummaryPlatelet function testing is both complex and labor intensive. A stepwise approach to the evaluation of patients with suspected platelet disorders will optimize the use of laboratory resources, beginning with an appropriate clinical evaluation to determine whether the bleeding is consistent with a defect of primary hemostasis.
openaire   +2 more sources

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

PSYNDEX Tests Review für MDT 8 - MATHEMATIK-DIDAKTISCHE TESTS FÜR DIE 8. SCHULSTUFE

, 1983
This is a PSYNDEX Tests Review of MDT 8 - MATHEMATIK-DIDAKTISCHE TESTS FÜR DIE 8. SCHULSTUFE. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Lukesch, Helmut
core   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

PSYNDEX Tests Review für WDG - WIENER DETERMINATIONSGERÄT

, 1988
This is a PSYNDEX Tests Review of WDG - WIENER DETERMINATIONSGERÄT. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Eberwein, Manfred
core   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Comparison of nine platelet function tests used to determine responses to different aspirin dosages in people with type 2 diabetes

Platelets, 2019
The antiplatelet efficacy of aspirin (ASA) is reduced in type 2 diabetes (T2D). As the best ex vivo method of measuring ASA efficacy remains uncertain, we compared nine platelet function tests to assess responsiveness to three ASA dosing regimens in 24 ...
Paul Harrison, M. Angelyn Bethel, Irene Kennedy, Robert Dinsdale, Ruth Coleman, Rury R. Holman   +5 more
doaj   +1 more source

PSYNDEX Tests Review für LFB-FOT - LEHRERFRAGEBOGEN ZUM EINSATZ FEHLERORIENTIERTER TESTS

, 1989
This is a PSYNDEX Tests Review of LFB-FOT - LEHRERFRAGEBOGEN ZUM EINSATZ FEHLERORIENTIERTER TESTS. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Eberwein, Manfred
core   +1 more source

Platelet function tests [PDF]

Biochemia medica, 2006
Trombociti (Trc) sudjeluju u održavanje normalne hemostaze adhezijom na mjestu ozljede krvne žile lučenjem sadržaja iz granula, agregacijom i stvaranjem primarnoga hemostatskog ugruška. Za njeno održavanje je, uz normalan broj Trc, neophodna i njihova normalna funkcija.
openaire  

Haemostasis alterations in immune thrombocytopenia and their clinical significance

Research and Practice in Thrombosis and Haemostasis
Immune thrombocytopenia (ITP) is highly heterogeneous, and only a subset of patients with severe thrombocytopenia develops significant bleeding. ITP is also associated with a paradoxical increased risk of thrombosis.
Thomas Pincez, Natalie Mathews, Arnaud Bonnefoy   +2 more
doaj   +1 more source