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Platelet dense granule defect: experience in the French population. [PDF]
Res Pract Thromb HaemostBorgel D +19 more
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Hematology/Oncology Clinics of North America, 2013
Platelet function tests have been traditionally used to aid in the diagnosis and management of patients with bleeding problems. Given the role of platelets in atherothrombosis, several dedicated platelet function instruments are now available that are simple to use and can be used as point-of-care assays.
Paul, Harrison, Marie, Lordkipanidzé
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Platelet function tests have been traditionally used to aid in the diagnosis and management of patients with bleeding problems. Given the role of platelets in atherothrombosis, several dedicated platelet function instruments are now available that are simple to use and can be used as point-of-care assays.
Paul, Harrison, Marie, Lordkipanidzé
openaire +4 more sources
The Platelet and Platelet Function Testing in Liver Disease
Clinics in Liver Disease, 2009Patients who have liver disease commonly present with alterations in platelet number and function. Recent data have questioned the contribution of these changes to bleeding complications in these patients. Modern tests of platelet function revealed compensatory mechanisms for the decreased platelet number and function, the most prominent compensatory ...
Hugenholtz, Greg G. C. +2 more
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The Lancet, 1969
The following platelet function tests are discussed: bleeding time, platelet retention tests, platelet aggregation, and radio-immunoassays for platelet release products, such as β thromboglobulin (βTG), and platelet factor 4 (PF4).
J W, ten Cate, S I, de Vries
+5 more sources
The following platelet function tests are discussed: bleeding time, platelet retention tests, platelet aggregation, and radio-immunoassays for platelet release products, such as β thromboglobulin (βTG), and platelet factor 4 (PF4).
J W, ten Cate, S I, de Vries
+5 more sources
Current Opinion in Hematology, 2007
Platelets play a vital role in the normal hemostasis, and derangements of their function can lead to hemorrhage or thrombosis. While we have made progress in elucidating the molecular mechanisms leading to platelet adhesion, aggregation, shape change, and secretion, clinically useful tests of platelet function have lagged behind.
Usman, Shah, Alice D, Ma
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Platelets play a vital role in the normal hemostasis, and derangements of their function can lead to hemorrhage or thrombosis. While we have made progress in elucidating the molecular mechanisms leading to platelet adhesion, aggregation, shape change, and secretion, clinically useful tests of platelet function have lagged behind.
Usman, Shah, Alice D, Ma
openaire +2 more sources
Standardization of platelet function tests
American Journal of Hematology, 1981AbstractMethods for the standardization of several currently used platelet function tests (bleeding time, capillary fragility, platelet retention, platelet aggregation, platelet factor 3, and platelet volume profiles) are presented. Different variables that may interfere with the reproducibility of the results of each assay were identified and ...
P R, Roper-Drewinko +5 more
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Contemporary platelet function testing
cclm, 2010Abstract Defects in primary hemostasis typically lead to a bleeding diathesis and include several disorders, such as von Willebrand disease and various platelet function defects that may arise because of failure of membrane receptors, deficiencies in internal storage organelles, and/or signal transduction problems.
Favaloro EJ +2 more
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Thrombosis Research, 1990
A method for screening EDTA(K3) blood samples for platelet function is described. The general availability of whole blood platelet counters in the clinical laboratory suggested their use to measure platelet aggregation. To simplify the collection and storage of blood samples, a method utilizing EDTA collected blood is described. Addition of calcium and
W L, Ryan, K, Hakenkamp, E, Sullivan
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A method for screening EDTA(K3) blood samples for platelet function is described. The general availability of whole blood platelet counters in the clinical laboratory suggested their use to measure platelet aggregation. To simplify the collection and storage of blood samples, a method utilizing EDTA collected blood is described. Addition of calcium and
W L, Ryan, K, Hakenkamp, E, Sullivan
openaire +2 more sources