Results 211 to 220 of about 7,899,636 (253)

Reproducibility of Platelet Function Testing

Laboratory Hematology, 2007
Platelet aggregation and release studies aid in the diagnosis of bleeding disorders. However, variability in normal individuals has not been established. We evaluated the variation in platelet aggregation and release testing over a period of 2 years with 59 observations among 5 subjects.
Megan E, Hevelow, Steven M, McKenzie, Jamie E, Siegel   +2 more
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Platelet function inhibitors and platelet function testing in neurointerventional procedures

Journal of NeuroInterventional Surgery, 2014
Over the past decade there has been a growing use of intracranial stents for the treatment of both ischemic and hemorrhagic cerebrovascular disease, including stents to assist in the remodeling of the neck of aneurysms as well as the use of flow diverting devices for aneurysm treatment.
Chirag D, Gandhi, Ketan R, Bulsara, Johanna, Fifi, Tareq, Kass-Hout, Ryan A, Grant, Josser E, Delgado Almandoz, Joey, English, Philip M, Meyers, Todd, Abruzzo, Charles J, Prestigiacomo, Ciaran James, Powers, Seon-Kyu, Lee, Barbara, Albani, Huy M, Do, Clifford J, Eskey, Athos, Patsalides, Steven, Hetts, M Shazam, Hussain, Sameer A, Ansari, Joshua A, Hirsch, Michael, Kelly, Peter, Rasmussen, William, Mack, G Lee, Pride, Michael J, Alexander, Mahesh V, Jayaraman   +25 more
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Platelet Function Testing in Atherothrombotic Disease

Current Pharmaceutical Design, 2012
Platelet function testing was introduced more than a century ago with the invention of bleeding time; a test which has now been replaced by more accurate methods. Light transmittance aggregometry is traditionally regarded as the gold standard for evaluating platelet function.
Grove, Erik Lerkevang; id_orcid 0000-0002-1466-0865, Storey, Robert F, Würtz, Morten; id_orcid 0000-0001-7150-7704   +2 more
openaire   +3 more sources

Platelet function tests

Turkish Journal of Biochemistry, 2014
Objective: Platelet function tests are recommended for patients when bleeding symptoms are not fully explained by standard laboratory investigations. In this report, we discussed ex vivo methods to evaluate platelet functions and and anti-platelet therapy.
DİKMEN, ZELİHA GÜNNUR, AKBIYIK, FİLİZ   +1 more
openaire   +3 more sources

Platelets and platelet function testing in children

Progress in Pediatric Cardiology, 2005
Abstract Platelets play key roles in hemostasis as well as in the pathogenesis of arterial thrombosis. This review summarizes current knowledge of the physiology of pediatric platelets; similarities and differences with platelets from adults are discussed with regards to platelet characteristics, adhesion, activation and secretion, and aggregation. A
Margaret L. Rand, Stefan Kuhle
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Whole Blood Platelet Aggregometry and Platelet Function Testing

Seminars in Thrombosis and Hemostasis, 2009
Platelet aggregometry has been the reference method employed to detect, diagnose, and monitor qualitative platelet disorders since the early 1960s. Lumiaggregometry and impedance-based whole blood lumiaggregometry have advantages over light transmittance aggregometry in that they provide for enhanced specimen management and increase the test ...
David L, McGlasson, George A, Fritsma
openaire   +2 more sources

Current Options in Platelet Function Testing

The American Journal of Cardiology, 2006
The variable response to antiplatelet therapy has led to the use of platelet function tests to monitor the effects of antiplatelet drugs in cardiovascular diseases. The goal is to guide antiplatelet therapy to the optimal dose for the prevention or treatment of thrombosis while minimizing hemorrhagic side effects.
Michelson, Alan D., Frelinger, Andrew L. III, Furman, Mark I.   +2 more
openaire   +3 more sources

Platelet function testing: state of the art

Expert Review of Cardiovascular Therapy, 2007
Platelet function testing has evolved from crude tests, such as the bleeding time, to tests that permit a relatively sophisticated evaluation of platelet activity. Nonetheless, these tests are hampered by lack of specificity and sensitivity, and poor standardization of methods and techniques.
Amer M, Zeidan, Peter A, Kouides, Mary Ann, Tara, William A, Fricke   +3 more
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Application of platelet function testing to the bedside

Thrombosis and Haemostasis, 2010
SummaryThe ability to test platelet reactivity in clinical practice could help in making informed decisions on both initiation and titration of anti-platelet drug therapies. However, many barriers still remain to the effective implementation of such techniques. Many tests used in the research literature are not yet available for practical, clinical use.
Craig D, Williams, Ganesh, Cherala, Victor, Serebruany   +2 more
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The Effect of Prednisone on Platelet Function Tests

Scandinavian Journal of Haematology, 1982
Ivy bleeding time, capillary fragility, threshold ADP concentration for secondary platelet aggregation and platelet adhesiveness were found to be unchanged by 2 d and 6 weeks of treatment with prednisone in 22 consecutive patients with collagen or haematological diseases.
K A, Jørgensen, L, Freund, P, Sørensen
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