Bioactive food components and their inhibitory actions in multiple platelet pathways
A comprehensive overview of platelet multifunctional roles in CVD and other diseases and the effects of food components' modulatory effects are described. Abstract In addition to hemostasis and thrombosis, blood platelets are involved in various processes such as inflammation, infection, immunobiology, cancer metastasis, wound repair and angiogenesis ...
Diptimayee Das+7 more
wiley +1 more source
Research progress on modification of hemodialysis membranes with anticoagulant properties [PDF]
The dialysis membrane is the most important component of hemodialyzer, and its performance depends on the feasibility and biocompatibility of removing toxic solutes.
Xuan WANG+5 more
doaj +1 more source
Liver‐directed drugs for transthyretin‐mediated amyloidosis
Abstract Transthyretin‐mediated amyloidosis (ATTR) is a rare, under‐recognized, progressively debilitating, fatal disease caused by the aggregation and extracellular deposition of amyloid transthyretin (TTR) fibrils in multiple organs and tissues throughout the body.
Thomas H. Brannagan 3rd+14 more
wiley +1 more source
New trends in the study of podoplanin as a cell morphological regulator
Podoplanin is a mucin-type glycoprotein firstly identified in podocytes, which is homologous to the type I alveolar cell specific T1α-2 antigen and to the oncofetal antigen M2A recognized by the D2-40 antibody. Podoplanin possesses a platelet aggregation-
Yoshihiko Sawa
doaj +1 more source
Advancements in left ventricular assist devices to prevent pump thrombosis and blood coagulopathy
Left ventricular assist device (LVAD)‐related blood coagulopathy: Pump thrombosis is one of the most severe adverse events caused by LVADs. The contact of blood with artificial materials of LVAD pumps and cannulas triggers the coagulation cascade. Abstract Mechanical circulatory support (MCS) devices, such as left ventricular assist devices (LVADs) are
Grainne Malone+12 more
wiley +1 more source
Platelet integrin αIIbβ3: signal transduction, regulation, and its therapeutic targeting
Integrins are a family of transmembrane glycoprotein signaling receptors that can transmit bioinformation bidirectionally across the plasma membrane.
Jiansong Huang+17 more
doaj +1 more source
ABSTRACT Cancer is a result of uncontrolled cell growth with the potential to damage or spread to another part of the body. It is the deadliest disease in the world; therefore, rapid and sensitive detection is essential to fight it. In the past few decades, many diagnosis tools have been developed to detect cancer and monitor therapy progress.
Md Mobarok Karim, Tahera Lasker
wiley +1 more source
Systemic lupus erythematosus and cardiovascular disease
Abstract The prognosis in systemic lupus erythematosus (SLE) has improved due to better treatment and care, but cardiovascular disease (CVD) still remains an important clinical problem, since the risk of CVD in SLE is much higher than among controls.
Johan Frostegård
wiley +1 more source
Cultured human endothelial cells synthesize a plasma membrane protein complex immunologically related to the platelet glycoprotein IIb/IIIa complex [PDF]
O. C. Leeksma+3 more
openalex +3 more sources
Platelet receptors and signaling in the dynamics of thrombus formation
Hemostasis and pathological thrombus formation are dynamic processes that require a co-ordinated series of events involving platelet membrane receptors, bidirectional intracellular signals, and release of platelet proteins and inflammatory substances ...
José Rivera+3 more
doaj +1 more source