Results 141 to 150 of about 119,694 (340)

A promising frontier of circulating messenger RNA in liquid biopsy: From mechanisms to clinical applications

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li   +7 more
wiley   +1 more source

Diagnostic and prognostic role of thrombospondin‐4 levels in pre‐eclampsia: Association with onset type, severity, and perinatal outcome

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the diagnostic and prognostic significance of maternal serum thrombospondin‐4 (TSP‐4) levels in pre‐eclampsia (PE), including comparisons between early‐ and late‐onset disease and between mild and severe cases, and to examine associations with adverse perinatal outcomes. Methods A prospective study was conducted including
Ruken Dayanan   +2 more
wiley   +1 more source

New trend in molecular diagnostics: Insights from the tumor microenvironment

open access: yesInterdisciplinary Medicine, EarlyView.
The graphical abstract outline the key elements in TME‐based molecular diagnostics, including biomarker exploration, diagnostic methods, and diagnostic models. Source: Created with BioRender.com. Abstract Molecular diagnosis has revolutionized cancer precision medicine.
Baiyuan Fan   +3 more
wiley   +1 more source

Engineering Efferocytosis for Bone Regeneration

open access: yesMacromolecular Bioscience, EarlyView.
The repair of bone tissue in acute and chronic injuries is a significant long‐standing clinical challenge. Biomaterials‐based interventions are well‐positioned to interrogate mechanisms of efferocytosis due to their ability to provide support and guide cellular activity.
Jacob Miszuk, Linna Zhong, Hongli Sun
wiley   +1 more source

Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine

open access: yesMacromolecular Bioscience, EarlyView.
This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro   +6 more
wiley   +1 more source

Substrate‐Dependent Variability in Viability and Angiogenic Marker Expression Among Three Endothelial Cell Subtypes: Insights for Artificial Tissue Vascularization

open access: yesMacromolecular Bioscience, EarlyView.
The study investigates how four ECM‐mimicking biomaterials—fibrin, fibronectin, and non‐crosslinked or crosslinked gelatin—affect different types of human endothelial cells. Cell viability, morphology, and angiogenic marker expression are evaluated. Results reveal substrate‐dependent effects on cell behavior and emphasize the importance of selecting ...
Jernej Vajda   +5 more
wiley   +1 more source

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