Results 161 to 170 of about 46,717 (298)

The Interaction Between Vasculogenic Mimicry and the Immune System: Mechanistic Insights and Dual Exploration in Cancer Therapy

open access: yesCell Proliferation, EarlyView.
VM is a novel form of angiogenesis discovered in many malignant tumours in recent years. And the well‐known immune response and related immune cells play different regulatory roles in the formation of VM. ABSTRACT Vasculogenic mimicry (VM) represents a novel form of angiogenesis discovered in numerous malignant tumours in recent years.
Shutong Liu   +14 more
wiley   +1 more source

Wound, pressure ulcer, and burn guidelines (2023)―4: Guidelines for the management of connective tissue disease/vasculitis‐associated skin ulcers, third edition

open access: yes
The Journal of Dermatology, EarlyView.
Yoshihide Asano   +27 more
wiley   +1 more source

New Anti‐Fibrotic Strategies for Keloids: Insights From Single‐Cell Multi‐Omics

open access: yesCell Proliferation, EarlyView.
Our research not only revealed the ubiquity and activity of POSTN‐positive mesenchymal fibroblasts in keloids but also discovered the predominant role of IGFBP2‐positive fibroblasts in normal skin and their potential significance in the process of anti‐fibrotic therapy.
Songyun Zhao   +16 more
wiley   +1 more source

Alternative proteolytic processing of platelet membrane glycoprotein IIb.

open access: hybrid, 1988
Joseph C. Loftus   +3 more
openalex   +1 more source

Aetiopathogenesis of infantile epileptic spasms syndrome and mechanisms of action of adrenocorticotrophin hormone/corticosteroids in children: A scoping review

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes   +6 more
wiley   +1 more source

Toward molecular phenotyping of temporal lobe epilepsy by spatial omics

open access: yesEpilepsia, EarlyView.
Abstract Objective In temporal lobe epilepsy (TLE), detection of the epileptogenic zone predicts a good surgical outcome. When submitted to 18F‐fluorodeoxyglucose positron emission tomography (PET), some patients display lateralized, focal hypometabolism in the temporal lobe (PET+), whereas others appear normometabolic (PET−).
Isabeau Vermeulen   +33 more
wiley   +1 more source

Extracellular vesicles in multiple myeloma: pathogenesis and therapeutic application

open access: yesThe FEBS Journal, EarlyView.
Multiple myeloma is characterised by the clonal proliferation of plasma cells in the bone marrow. Extracellular vesicles (EVs) are a key component of cell‐to‐cell communication within the bone marrow microenvironment, promoting tumour growth, bone remodelling, immune modulation, angiogenesis and therapeutic resistance.
Chloe Wylie   +3 more
wiley   +1 more source

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