Results 11 to 20 of about 116,983 (327)

Identification of the platelet-specific alloantigen, Naka, on platelet membrane glycoprotein IV [PDF]

Blood, 1990
Abstract We describe the membrane localization of a new platelet-specific alloantigen, designated Naka, that is involved in refractoriness to HLA- matched platelet transfusions. By indirect immunoprecipitation, anti- Naka antibody precipitated a single, radiolabeled platelet membrane protein with a molecular weight (mol wt) of 91 Kd from
S Sekiguchi, Takayasu Furubayashi, Hironori Take, Hajime Mizutani, T Mitani, GA Jamieson, NN Tandon, Hirokazu Ikeda, Yoshiaki Tomiyama, Naoko Yamamoto   +9 more
openaire   +4 more sources

Isolation and Quantitation of the Platelet Membrane Glycoprotein Deficient in Thrombasthenia Using a Monoclonal Hybridoma Antibody [PDF]

Journal of Clinical Investigation, 1980
We used the hybridoma technique to characterize further the platelet glycoprotein abnormality in Glanzmann's thrombasthenia. Spleen cells from Balb/c mice immunized with human platelets were fused to mouse myeloma cell line Sp2/0-Ag14.
Rodger P. McEver, Nancy Lewis Baenziger, Philip W. Majerus   +2 more
openalex   +2 more sources

Thrombin-induced platelet membrane glycoprotein IIb and IIIa complex formation. An electron microscope study.

Journal of Experimental Medicine, 1981
The topographic relationships of platelet membrane glycoprotein IIb and glycoprotein IIIa have been studied in stimulated and unstimulated human platelets using immunoelectron microscopy.
Margaret J. Polley, Lawrence Leung, F Y Clark, Ralph L. Nachman   +3 more
openalex   +2 more sources

Structural analysis of human platelet membrane glycoprotein I complex.

Proceedings of the National Academy of Sciences of the United States of America, 1979
The glycoprotein I complex, consisting of two polypeptides of Mr 210,000 and 150,000, was isolated from human platelet membranes by wheat germ lectin affinity chromatography.
Ralph L. Nachman, Tadatoshi Kinoshita, Barbara Ferris   +2 more
openalex   +2 more sources

The Streptococcus gordonii Surface Proteins GspB and Hsa Mediate Binding to Sialylated Carbohydrate Epitopes on the Platelet Membrane Glycoprotein Ibα

Infection and Immunity, 2004
Barbara A. Bensing, José A. López, Paul M. Sullam   +2 more
openalex   +2 more sources

Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation.

Journal of Biological Chemistry, 1985
Sanford J. Shattil, James A. Hoxie, Michael Cunningham, L F Brass   +3 more
openalex   +2 more sources

Isolation and characterization of the major oligosaccharide of human platelet membrane glycoprotein GPIb. [PDF]

Biochemical Journal, 1982
Treatment of intact human platelets with chymotrypsin released a glycopolypeptide that was shown to be derived from the major membrane glycoprotein, GPIb.
P. Judson, D. Anstee, John R. CLAMPt
openalex   +2 more sources

Interaction of calmodulin with the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex

Blood, 2001
Engagement of platelet membrane glycoprotein (GP) Ib-IX-V by von Willebrand factor triggers Ca(++)-dependent activation of alphaIIbbeta3, resulting in (patho)physiological thrombus formation. It is demonstrated here that the cytoplasmic domain of GPIb-IX-
Robert K. Andrews, Adam D. Munday, Christina A. Mitchell, Michael C. Berndt   +3 more
openalex   +2 more sources

Desialylation of platelets induced by Von Willebrand Factor is a novel mechanism of platelet clearance in dengue. [PDF]

PLoS Pathogens, 2019
Thrombocytopenia and platelet dysfunction are commonly observed in patients with dengue virus (DENV) infection and may contribute to complications such as bleeding and plasma leakage.
Silvita Fitri Riswari, Rahajeng N Tunjungputri, Vesla Kullaya, Fadel M Garishah, Gloria S R Utari, Nur Farhanah, Gijs J Overheul, Bachti Alisjahbana, M Hussein Gasem, Rolf T Urbanus, Philip G de Groot, Dirk J Lefeber, Ronald P van Rij, Andre van der Ven, Quirijn de Mast   +14 more
doaj   +1 more source

Stimulation of platelet production: the new treatment approach to chronic immune thrombocytopenic purpura

Онкогематология, 2022
Chronic immune thrombocytopenic purpura (ITP) is one of the most frequent immune hematological disorders in which development the leading part is played by the antibodies directed against a narrow spectrum of platelet antigens.
A. A. Maschan, A. G. Rumyantsev
doaj   +1 more source