Results 11 to 20 of about 131,155 (303)

Investigation of interaction of human platelet membrane components with anticoagulant drugs Abciximab and Eptifibatide.

open access: yesFolia Histochemica et Cytobiologica, 2011
Abciximab (Abci) and eptifibatide (Epti) are antiaggregate drugs which may reduce thrombotic complications in acute coronary syndromes. The aim of this work was the investigation of the interaction between the phospholipid-GPIIb/IIIa glycoprotein complex
Anna Sankiewicz   +2 more
doaj   +1 more source

Desialylation of platelets induced by Von Willebrand Factor is a novel mechanism of platelet clearance in dengue. [PDF]

open access: yesPLoS Pathogens, 2019
Thrombocytopenia and platelet dysfunction are commonly observed in patients with dengue virus (DENV) infection and may contribute to complications such as bleeding and plasma leakage.
Silvita Fitri Riswari   +14 more
doaj   +1 more source

Stimulation of platelet production: the new treatment approach to chronic immune thrombocytopenic purpura

open access: yesОнкогематология, 2022
Chronic immune thrombocytopenic purpura (ITP) is one of the most frequent immune hematological disorders in which development the leading part is played by the antibodies directed against a narrow spectrum of platelet antigens.
A. A. Maschan, A. G. Rumyantsev
doaj   +1 more source

Molecular study of sticky platelet syndrome using exome sequencing

open access: yesRevista de la Facultad de Medicina, 2021
Introduction: Sticky platelet syndrome (SPS) is a prothrombotic condition characterized by increased platelet aggregation that causes arterial and venous thrombosis.
Jaime José Pérez-Niño   +5 more
doaj   +1 more source

Convergent evolution of pregnancy-specific glycoproteins in human and horse [PDF]

open access: yes, 2016
Pregnancy-specific glycoproteins (PSGs) are members of the carcinoembryonic antigen cell adhesion molecule (CEACAM) family that are secreted by trophoblast cells. PSGs may modulate immune, angiogenic and platelet responses during pregnancy.
Amanda M de Mestre   +16 more
core   +2 more sources

Association of Platelet Desialylation and Circulating Follicular Helper T Cells in Patients With Thrombocytopenia

open access: yesFrontiers in Immunology, 2022
Thrombocytopenia is a multifactorial condition that frequently involves concomitant defects in platelet production and clearance. The physiopathology of low platelet count in thrombocytopenia remains unclear. Sialylation on platelet membrane glycoprotein
Yuwen Chen   +12 more
doaj   +1 more source

Identification of Potential Drug Targets for Antiplatelet Therapy Specifically Targeting Platelets of Old Individuals through Proteomic Analysis

open access: yesBiomedicines, 2023
Aging is a growing problem worldwide, and the prevalence and mortality of arterial and venous thromboembolism (VTE) are higher in the elderly than in the young population. To address this issue, various anticoagulants have been used. However, no evidence
Seung Hee Lee   +6 more
doaj   +1 more source

Platelet-collagen adhesion: evidence for participation of antigenically distinct entities. [PDF]

open access: yes, 1984
Univalent antibody fragments prepared from a rabbit antiserum raised against whole human platelets completely inhibited adhesion of platelets to immobilized trimeric collagen in a defined, Mg2+-dependent, adhesion assay.
Barondes, SH, Shadle, PJ
core   +2 more sources

An overview about erythrocyte membrane [PDF]

open access: yes, 2010
© 2010 – IOS Press and the authors. All rights reservedIn the sixties and seventies, erythrocytes or red blood cells (RBCs) were extensively studied. Much has been learnt particularly concerning their metabolism and gas transporter function. In the past
Oliveira, Sofia de, Saldanha, Carlota
core   +1 more source

Successful Management of Acute Catastrophic Juvenile Vaginal Bleeding in Glanzmann’s Thromboasthenia by Uterine Tamponade: A Case Report and Review of The Literature

open access: yesCase Reports in Hematology, 2012
Glanzmann’s thromboasthenia (GT) is a rare platelet disorder, due to membrane defects involving glycoprotein GP IIb/IIIa complex. Symptoms appear in infancy with episodes of bruising, gingival bleeding, epistaxis, or at the time of menarche acute episode
Nazli Hossain   +2 more
doaj   +1 more source

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