Results 191 to 200 of about 116,983 (327)

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, Volume 12, Issue 27, July 17, 2025.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidian Chen   +21 more
wiley   +1 more source

Extracellular vesicles in atherosclerosis cardiovascular disease: emerging roles and mechanisms. [PDF]

Front Cardiovasc Med
Deng H, Qiu W, Zhang Y, Hua J.
europepmc   +1 more source

Conformational changes in fibrinogen elicited by its interaction with platelet membrane glycoprotein GPIIb-IIIa.

, 1993
Tatiana P. Ugarova, Andrei Z. Budzynski, Sanford J. Shattil, Zaverio M. Ruggeri, Mark H. Ginsberg, Edward F. Plow   +5 more
openalex   +1 more source

Comprehensive characterization of the RNA editing landscape in the human aging brains with Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract INTRODUCTION While RNA editing has been linked to Alzheimer's disease (AD), its specific impact on the transcriptomic landscape in human AD brains remains under explored. METHODS We conducted a comprehensive analysis of RNA editing across nine human brain regions affected by AD, utilizing RNA‐seq data and matched whole‐genome sequencing data ...
Amit Kumar Gupta, William Martin, Andrew A. Pieper, Yinsheng Wang, Andrew J. Saykin, Feixiong Cheng   +5 more
wiley   +1 more source

Anesthesia Management Using Remimazolam in A Patient With Bernard-Soulier Syndrome: A Case Report. [PDF]

Clin Case Rep
Shakuo T, Ishida Y, Sugawara D, Ryo M, Okazaki H, Oe K.   +5 more
europepmc   +1 more source

Proteomic Profiling of the Large‐Vessel Vasculitis Spectrum Identifying Shared Signatures of Innate Immune Activation and Stromal Remodeling

Arthritis &Rheumatology, Volume 77, Issue 7, Page 884-900, July 2025.
Objective Takayasu arteritis (TAK) and giant cell arteritis (GCA), the most common forms of large‐vessel vasculitis (LVV), can result in serious morbidity. Understanding the molecular basis of LVV should aid in developing better biomarkers and treatments. Methods Plasma proteomic profiling of 184 proteins was performed in two cohorts. Cohort 1 included
Robert T. Maughan, Erin Macdonald‐Dunlop, Lubna Haroon‐Rashid, Louise Sorensen, Natalie Chaddock, Shauna Masters, Andrew Porter, Marta Peverelli, Charis Pericleous, Andrew Hutchings, James Robinson, Taryn Youngstein, Raashid A. Luqmani, Justin C. Mason, Ann W. Morgan, James E. Peters   +15 more
wiley   +1 more source

Platelets in cancer and immunotherapy: functional dynamics and therapeutic opportunities. [PDF]

Exp Hematol Oncol
Cai C, Liu Y, Lu R, Fan X, Zeng S, Gan P.   +5 more
europepmc   +1 more source

Efficient plasma membrane expression of a functional platelet glycoprotein Ib-IX complex requires the presence of its three subunits.

, 1992
José A. López, Betty Leung, C C Reynolds, Chen-Liang Li, Joyce E. Fox   +4 more
openalex   +1 more source

Harnessing the Nutritional Value, Therapeutic Applications, and Environmental Impact of Mushrooms

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
Mushrooms are highly nutritious, packed with vitamins, minerals, antioxidants, essential amino acids, and bioactive compounds. They offer various health benefits, including boosting immunity, reducing inflammation, and supporting gut and cardiovascular health. Rich in carbohydrates, quality protein, essential fatty acids, and both soluble and insoluble
Solomon Fitsum, Desta Berhe Sbhatu, Gebreselema Gebreyohannes   +2 more
wiley   +1 more source

IL-6 as a Mediator of Platelet Hyper-Responsiveness. [PDF]

Cells
Webb CE, Vautrinot J, Hers I.
europepmc   +1 more source