Results 221 to 230 of about 83,070 (313)

Automated Quantitative Immunofluorescence Microscopy Approach for Diagnosis of Hereditary Thrombopathies: A Proof of Concept Using Bernard-Soulier Syndrome and Glanzmann Thrombasthenia. [PDF]

Genes (Basel)
Loos K, Al-Rifai R, Ohlenforst S, Klein C, Oldenburg J, Pavlova A, Pezeshkpoor B.   +6 more
europepmc   +1 more source

Autoantibodies against platelet membrane glycoproteins in children with acute and chronic immune thrombocytopenic purpura

, 1989
Peter Berchtold, R McMillan, P Tani, S Sommerville-Nielsen, V. Blanchette   +4 more
openalex   +1 more source

Crossed immunoelectrophoresis of human platelet membranes. Effect of charge on association and dissociation of the glycoprotein GPIIb-GPIIIa membrane complex.

, 1986
Simon Karpatkin, R Ferziger, David M. Dorfman   +2 more
openalex   +1 more source

Nanotechnology and cell death: Revolutionizing disease treatment with nanoparticle strategies

VIEW, Volume 6, Issue 5, October 2025.
Traditional disease treatments often face issues such as poor drug targeting and significant side effects, with many complex diseases lacking effective therapies. Our research utilizes tiny nanomaterials to treat diseases by regulating natural cell death processes, improving the immune environment, etc., enabling drugs to act more precisely.
Yiwen Wan, Wangzheqi Zhang, Yan Liao, Chenglong Zhu, Xiaojing Guo, Zui Zou, Mi Li   +6 more
wiley   +1 more source

Fractions from Sea Buckthorn Seeds and Their Bioactive Ingredients as Modulators of Human Blood Platelet Response In Vitro: The Role of Thermal Processing. [PDF]

Nutrients
Sławińska N, Janko L, Żuchowski J, Olas B.   +3 more
europepmc   +1 more source

Insights into the clinical, platelet and genetic landscape of inherited thrombocytopenia with malignancy risk

British Journal of Haematology, Volume 207, Issue 4, Page 1565-1577, October 2025.
Inherited thrombocytopenia (IT) caused by germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk of developing haematological malignancy. This study examined the clinical, platelet and molecular characteristics of 66 patients with these conditions, who carried 24 distinct genetic variants in the corresponding genes.
Ana Marín‐Quílez, Ana Sánchez‐Fuentes, Ana Zamora‐Cánovas, Pedro Luis Gómez‐González, Lorena Diaz‐Ajenjo, Rocío Benito, Agustín Rodríguez‐Alén, Teresa Sevivas, Thais Murciano, Laura Murillo, Nora V. Butta, Nuria Revilla, Rosa Campos, Paola Escribano, Jordi Esteve, Nuria Fernández‐Mosteirin, Francisca Ferrer‐Marín, Laura Hernández, Jorge Huerta‐Aragonés, Antonio León, Mónica López‐Duarte, Eugenia López, Mónica Martín‐Salces, Meritxell Nomdedeu, Raquel Oña, Irene Peláez‐Pleguezuelos, Fernando Ramos, Elena Sebastián, Claudia Serrano, Cristina Sierra‐Aisa, Rosa Vidal‐Laso, José Ramón González‐Porras, María Luisa Lozano, José María Bastida, José Rivera   +34 more
wiley   +1 more source

Contrasting Effects of Platelet GPVI Deletion Versus Syk Inhibition on Mouse Jugular Vein Puncture Wound Structure. [PDF]

Int J Mol Sci
Pokrovskaya ID, Ball KK, Webb MW, Joshi S, Rhee SW, Ware J, Storrie B.   +6 more
europepmc   +1 more source

BCL‐2 Inhibitor Regulates Number, Function, and Antitumor Immunity of T Cells by Influencing Glycolysis in AML

Cancer Science, Volume 116, Issue 10, Page 2657-2676, October 2025.
This study found that BCL‐2 inhibitors can effectively induce AML cell apoptosis and regulate the proportion of lymphocytes to affect the AML tumor immune microenvironment. Furthermore, BCL‐2 inhibitor regulated the number, function, and activation status of T cells, thereby enhancing T cell‐mediated antitumor immune responses.
Xiaohuan Peng, Yanhong Li, Futian Tang, Yanling Ma, Jun Bai, Lijuan Li, Liansheng Zhang   +6 more
wiley   +1 more source

Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration

Cell Proliferation, Volume 58, Issue 10, October 2025.
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen, Haijun Zhang, Zhaoheng Wang, Daxue Zhu, Yanhu Li, Yizhi Zhang, Dongxin Wang, Shuwei Chen, Huan Liu, Xuewen Kang   +9 more
wiley   +1 more source

Effective treatment with daratumumab in post-HSCT refractory immune-mediated cytopenias: a case report and literature review. [PDF]

Front Immunol
Jing XY, Li DJ, Su SN, Dai QK, Sun SW, Huang L, Ai Y, Gao J, Zhu YP, Ni JQ, Lu XX.   +10 more
europepmc   +1 more source