Results 261 to 270 of about 131,155 (303)

P-Selectin Glycoprotein Ligand (PSGL)-1 Expression on CD4⁺ T Cells in Patients with HIV: Insights from an Observational Study. [PDF]

Pathogens
Zaongo SD, Wan Y, Zhang L, Tang S, Harypursat V, Chen Y.   +5 more
europepmc   +1 more source

CDG due to Defective Membrane Transporters: Update

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Congenital disorders of glycosylation are genetic defects in the glycoprotein and glycolipid glycan assembly and attachment. Some 200 CDG have been reported since the first clinical description in 1980. Most CDG are enzymatic deficiencies, but 13 (6.5%) are defects in the ER, Golgi apparatus (GA), and plasma membrane transporters.
D. Quelhas, C. R. Ferreira, J. Jaeken
wiley   +1 more source

A Case of Piperacillin-Induced Immune Thrombocytopenia: Diagnostic Challenges and Management. [PDF]

Cureus
Patel A, Atodaria K, Rettew AC, Kottapalli N, Tetali P.   +4 more
europepmc   +1 more source

The Role of Macrophages in Cancer: From Basic Research to Clinical Applications

MedComm, Volume 7, Issue 1, January 2026.
Monocytes infiltrate the tumor microenvironment (TME) and differentiate into macrophages, which polarize into proinflammatory, antitumor M1 cells or immunosuppressive, protumor M2 cells. Within the TME, M2‐type tumor‐associated macrophages (TAMs) predominate and drive tumor growth, angiogenesis, and metastasis. Therapeutic strategies therefore focus on
Zhimei Liu, Yan Li, Jingchao Cao, Yefeng Qiu, Kun Yu, Shoulong Deng   +5 more
wiley   +1 more source

ITGA2B/ITGB3-Related Macrothrombocytopenia Associated With Gain-of-Function Mutations in ITGA2B or ITGB3 Genes. [PDF]

J Cell Mol Med
Wu J, Yan H, Li Z, Zhu Y, Shao R, Xin H, Jia T, Ge M, Zhang L, Jiang S, Mao J, Huang J, Fang C, Xi X, Shi X.   +14 more
europepmc   +1 more source

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

Medicinal Research Reviews, Volume 46, Issue 1, Page 149-175, January 2026.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca, Gianluca Baldanzi, Alberto Massarotti   +2 more
wiley   +1 more source

Giant platelets and persistent bleeding: a pediatric case of Bernard-Soulier syndrome. [PDF]

Ann Med Surg (Lond)
Bhavana B, Sandesara M, Gyanendra KC, Bopparaju S, Swapnik K, Nabgouri Y, Zehra O, Rana F, Garapati A, Mateen MA, Hamza Abdel Ghani E.   +10 more
europepmc   +1 more source

Non‐Targeted Analysis of Extracellular Vesicle‐Enriched Plasma Proteome Between Early and Late Rugby Playing Career

PROTEOMICS – Clinical Applications, Volume 20, Issue 1, January 2026.
ABSTRACT Purpose Rugby players experience high‐impact collisions, potentially increasing their risk of neurodegenerative conditions. This study investigates whether the plasma proteome of extracellular vesicles (EV) provides biomarkers to indicate differential risk associated with a rugby career.
Abhishek Jagan, Yusuke Nishimura, Tim Donovan, Jatin G. Burniston   +3 more
wiley   +1 more source

CD42-Enriched Extracellular Vesicles Contribute to Increased Platelet Aggregation and Possibly Organ Damage in Patients with Burn Injury Complicated by Sepsis. [PDF]

Int J Nanomedicine
Schiavello M, Vizio B, Bosco O, Mariano F, Bruno S, Pensa A, Cagna Vallino P, Dini C, Montrucchio G, Lupia E.   +9 more
europepmc   +1 more source