Results 271 to 280 of about 131,155 (303)

Exosome‐Based Cartilage‐Targeted Delivery System: Strategies and Applications

Small Science, Volume 6, Issue 1, January 2026.
Construction strategies and applications of cartilage‐targeting exosomes. With the ageing of the global population, cartilage‐related diseases, such as osteoarthritis (OA) and intervertebral disc degeneration (IVDD), have increasingly become significant social problems threatening human health. Therefore, targeted therapy for cartilage is becoming more
Yao Wang, Bo Chen, Haodong Zhu, Zhenyu Sun   +3 more
wiley   +1 more source

Biomechanical platelet activation: diseases that require a new class of antiplatelet therapeutics. [PDF]

Am J Physiol Cell Physiol
Gupta R, Alkhalfan F, Wheeler J, Cameron SJ.   +3 more
europepmc   +1 more source

Hydrogel Microspheres for Biomedical Applications

Small Science, Volume 6, Issue 1, January 2026.
Hydrogel microspheres (HMs) play pivotal roles in biomedical applications, such as drug delivery, cell culture, regenerative medicine, wound healing, and tumor immunity. This review focuses on the latest findings to provide a more comprehensive understanding of HMs for biomedical applications.
Yingkang Huang, Xi Zhu, Jinhong Zhou, Henan Li, Wei Zhang, Danyang Shen, Ziyan Huang, Tianbo Zhang, Lin Zhuang, Lei Qin, Xiaofeng Xue, Yunjie Lu   +11 more
wiley   +1 more source

CD147 at the crossroads of glycoprotein networks, metabolic reprogramming, and metastatic progression. [PDF]

Front Immunol
Su TS, Wang JW, Su YL, Lin MH, Chiou HC.
europepmc   +1 more source

Polydopamine‐Based Antioxidant Countermeasures Against Spaceflight‐Induced Neurodegeneration

Small Science, Volume 6, Issue 1, January 2026.
Polydopamine nanoparticles (PDNPs) protect neuron‐like cells from microgravity‐ and cosmic radiation‐induced oxidative stress. Through in‐flight and ground‐based experiments, it has been shown that PDNPs preserve neuronal and mitochondrial function, markedly mitigating transcriptional dysregulation caused by spaceflight.
Alessio Carmignani, Attilio Marino, Matteo Battaglini, Melike Belenli Gümüş, Elisa Carrubba, Michele Balsamo, Giovanni Valentini, Gabriele Mascetti, Marco Vukich, Giada Graziana Genchi, Gianni Ciofani   +10 more
wiley   +1 more source

High glucose enhances inflammation-driven platelet adhesion to endothelial cells in vitro. [PDF]

Sci Rep
Scavone M, Fioretti A, Molinaro M, Ghali C, Martinelli C, Mencarini T, Bozzi S, Santo N, Gianelli U, Miozzo M, Guazzi M, Podda GM, Cozzolino M, Ciceri P.   +13 more
europepmc   +1 more source

Self‐Organizing Ovarian Somatic Organoids Preserve Cellular Heterogeneity and Reveal Cellular Contributions to Ovarian Aging

Aging Cell, Volume 25, Issue 1, January 2026.
We report the development and application of a mouse ovarian somatic organoid model to elucidate a fundamental new understanding of the cell biology of the aging ovarian microenvironment. ABSTRACT Ovarian somatic cells are essential for reproductive function, but no existing ex vivo models recapitulate the cellular heterogeneity or interactions within ...
Shweta S. Dipali, Aubrey Converse, Madison Q. Gowett, Pratik Kamat, Emily J. Zaniker, Abigail Fennell, Teresa Chou, Michele T. Pritchard, Mary Zelinski, Jude M. Phillip, Francesca E. Duncan   +10 more
wiley   +1 more source

A minimum valency of 4 is required for robust activation of platelets in flow cytometry by multivalent nanobodies to Glycoprotein VI, C-type lectin-like receptor 2 and Platelet Endothelial Aggregation Receptor 1. [PDF]

Res Pract Thromb Haemost
Lamerton RE, Martin EM, Perry J, Cunningham AF, Watson SP, Frelinger AL.   +5 more
europepmc   +1 more source

Primary Antiphospholipid Syndrome Presenting With Life-Threatening Diffuse Alveolar Hemorrhage. [PDF]

Cureus
Casanova Pinto J, Costa MG, Fernandes B, Ramalheira C.   +3 more
europepmc   +1 more source

Postoperative Thrombocytopenia in Cardiac Surgery: Patterns, Differential Diagnosis and Management of Heparin-Induced Thrombocytopenia (HIT). [PDF]

J Clin Med
Ampatzidou F, Argyriadou E, Amaniti C, Sarridou D.   +3 more
europepmc   +1 more source