Results 21 to 30 of about 83,070 (313)
Platelet Membrane Glycoproteins: A Historical Review [PDF]
Seminars in Thrombosis and Hemostasis, 2014 The search for the components of the platelet surface that mediate platelet adhesion and platelet aggregation began for earnest in the late 1960s when electron microscopy demonstrated the presence of a carbohydrate-rich, negatively charged outer coat that was called the "glycocalyx." Progressively, electrophoretic procedures were developed that ...
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CHIMIA, 1976 The treatment of washed, intact human blood platelets with 1 U/ml of thrombin for 5 min at 37 °C is linked to the disappearance from the particulate fraction of the homogenized cells of a protein band discernible in the SDS-polyacrylamide gel ...
R. Käser-Glanzmann +2 more
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Glanzmann’s thrombasthenia with spontaneous upper gastrointestinal bleeding: a case report
Journal of International Medical Research, 2020 Glanzmann’s thrombasthenia (GT) is a rare bleeding disorder inherited in an autosomal recessive manner. The pathogenesis of GT mainly involves structural abnormalities and dysfunction of platelet membrane glycoprotein IIb/IIIa (integrin αIIbβ3). The most
Zhenguo Qiao +5 more
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Two Arginine Residues of Streptococcus gordonii Sialic Acid-Binding Adhesin Hsa Are Essential for Interaction to Host Cell Receptors. [PDF]
PLoS ONE, 2016 Hsa is a large, serine-rich protein of Streptococcus gordonii DL1 that mediates binding to α2-3-linked sialic acid termini of glycoproteins, including platelet glycoprotein Ibα, and erythrocyte membrane protein glycophorin A, and band 3.
Yumiko Urano-Tashiro +3 more
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Platelets, 2017 Platelet membrane bedecked with a wide array of receptors offers a platform to regulate platelet responsiveness, thrombotic propensity, inflammatory disposition, and immune reactivity under diverse pathophysiological conditions.
Madhumita Chatterjee, Meinrad Gawaz
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Therapeutic Advances in Chronic Disease, 2022 Von Willebrand factor (VWF) is a glycoprotein synthesized and secreted by vascular endothelial cells and megakaryocytes, found on plasma surface, endothelial cells, and α-granule of platelets.
Qiong Xiang +4 more
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Regulation of platelet membrane protein shedding in health and disease
Platelets, 2017 Extracellular proteolysis of platelet plasma membrane proteins is an event that ensues platelet activation. Shedding of surface receptors such as glycoprotein (GP) Ibα, GPV and GPVI as well as externalized proteins P-selectin and CD40L releases soluble ...
Amanda E. Au, Emma C. Josefsson
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Isolation of Some Platelet Membrane Glycoproteins [PDF]
Thrombosis and Haemostasis, 1977 The platelet is surrounded by a pronounced glycocalix formed by carbohydrate moieties of the membrane glycoproteins. The number of glycoproteins of the outer platelet membrane is greater in number than had previously been reported : when solubilized membranes are analyzed by SDS-polyacrylamide gel electrophoresis the number of separated carbohydrate ...
C. S. P. Jenkins +4 more
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Egyptian Journal of Medical Human Genetics, 2019 Background The fibrinogen receptor is an integrin on the platelet surface and is shaped from two types of glycoprotein (GP) subunits, GPIIb and GPIIIa. Membrane glycoprotein IIb/IIIa plays an important role in platelet function.
Zahra Rezaei Dezaki +2 more
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Scientific Reports, 2023 Receptor diffusion plays an essential role in cellular signalling via the plasma membrane microenvironment and receptor interactions, but the regulation is not well understood.
Chukiat Tantiwong +6 more
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