Results 21 to 30 of about 116,983 (327)

Computer Simulation of Platelet Adhesion around Stent Struts in the Presence and Absence of Tissue Defects around Them

open access: yesJournal of Interventional Cardiology, 2021
Aim. To predict platelet accumulation around stent struts in the presence or absence of tissue defects around them. Methods. Computer simulations were performed using virtual platelets implementing the function of the three membrane proteins ...
Yota Kawamura   +3 more
doaj   +1 more source

Molecular study of sticky platelet syndrome using exome sequencing

open access: yesRevista de la Facultad de Medicina, 2021
Introduction: Sticky platelet syndrome (SPS) is a prothrombotic condition characterized by increased platelet aggregation that causes arterial and venous thrombosis.
Jaime José Pérez-Niño   +5 more
doaj   +1 more source

Human platelet membrane receptor for bovine von Willebrand factor (platelet aggregating factor): an integral membrane glycoprotein.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1979
The platelet membrane receptor for bovine von Willebrand factor, platelet aggregating factor, has been reported to be a property of a soluble glycoprotein, glycocalicin, that is loosely attached to the platelet surface and represents one of the major ...
H. Cooper, K. Clemetson, E. Lüscher
semanticscholar   +1 more source

Association of Platelet Desialylation and Circulating Follicular Helper T Cells in Patients With Thrombocytopenia

open access: yesFrontiers in Immunology, 2022
Thrombocytopenia is a multifactorial condition that frequently involves concomitant defects in platelet production and clearance. The physiopathology of low platelet count in thrombocytopenia remains unclear. Sialylation on platelet membrane glycoprotein
Yuwen Chen   +12 more
doaj   +1 more source

Interaction of purified type IIB von Willebrand factor with the platelet membrane glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and initiates aggregation.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1985
Von Willebrand factor (vWF) was purified from the plasma of a patient with type IIB von Willebrand disease (vWF from such a patient, IIB vWF) who had a normal platelet count and showed no evidence of spontaneous platelet aggregation.
L. D. Marco   +3 more
semanticscholar   +1 more source

Identification of Potential Drug Targets for Antiplatelet Therapy Specifically Targeting Platelets of Old Individuals through Proteomic Analysis

open access: yesBiomedicines, 2023
Aging is a growing problem worldwide, and the prevalence and mortality of arterial and venous thromboembolism (VTE) are higher in the elderly than in the young population. To address this issue, various anticoagulants have been used. However, no evidence
Seung Hee Lee   +6 more
doaj   +1 more source

Specific labelling of platelet membrane glycoproteins

open access: yesFEBS Letters, 1980
The glycoproteins present on the platelet membrane are considered to be of great importance to platelet activities [ 1,2]. Few pathological platelet membrane glycoprotein abnormalities are known and ,usually they result in disturbance of aggregation.
Avner Rotman   +2 more
openaire   +3 more sources

Successful Management of Acute Catastrophic Juvenile Vaginal Bleeding in Glanzmann’s Thromboasthenia by Uterine Tamponade: A Case Report and Review of The Literature

open access: yesCase Reports in Hematology, 2012
Glanzmann’s thromboasthenia (GT) is a rare platelet disorder, due to membrane defects involving glycoprotein GP IIb/IIIa complex. Symptoms appear in infancy with episodes of bruising, gingival bleeding, epistaxis, or at the time of menarche acute episode
Nazli Hossain   +2 more
doaj   +1 more source

Amino acid sequence of the von Willebrand factor-binding domain of platelet membrane glycoprotein Ib.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1987
We report the amino acid sequence of a 299-residue segment from the alpha chain of the human platelet membrane glycoprotein Ib. This includes the complete sequence of the amino-terminal tryptic fragment of 290 residues comprising the von Willebrand ...
K. Titani   +3 more
semanticscholar   +1 more source

Platelet Membrane Glycoproteins: A Historical Review [PDF]

open access: yesSeminars in Thrombosis and Hemostasis, 2014
The search for the components of the platelet surface that mediate platelet adhesion and platelet aggregation began for earnest in the late 1960s when electron microscopy demonstrated the presence of a carbohydrate-rich, negatively charged outer coat that was called the "glycocalyx." Progressively, electrophoretic procedures were developed that ...
openaire   +2 more sources

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